8 completed, 1 unknown. 9 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 8, Unknown 1 |
Follow Mechlorethamine: new trials by email Literature Review of Mechlorethamine trials Research Report on Mechlorethamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Valchlor in the Treatment of Lichen Planopilaris Mechlorethamine 0.016% Top Gel - Lichen Planopilaris | Phase 2 | Completed | Mayo Clinic | 12 | 2018-04-01 | 2021-01-28 |
| Mechlorethamine Induced Contact Dermatitis Avoidance Study Triamcinolone, Valchlor 0.016 % Topical Gel - Cutaneous T-cell Lymphoma, Cutaneous T-cell Lymphoma Stage I | Phase 2 | Completed | Rochester Skin Lymphoma Medical Group, PLLC | 28 | 2017-12-13 | 2026-09-04 |
| Combination Chemotherapy Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or High-Risk Primary Refractory Hodgkin Lymphoma cyclophosphamide, cyclosporine, fludarabine phosphate - Lymphoma | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 25 | 2007-11-13 | 2023-09-28 |
| Chemotherapy With Low-Dose Radiation for Pediatric Hodgkin Lymphoma Adriamycin®, Vinblastine, Nitrogen Mustard - Hodgkin's Lymphoma | Phase 2 | Completed | St. Jude Children's Research Hospital | 81 | 2006-07-20 | 2023-09-22 |
| Safety and Efficacy of Nitrogen Mustard in Treatment of Mycosis Fungoides mechlorethamine-MCH (nitrogen mustard) - Mycosis Fungoides | Phase 2 | Completed | Yaupon Therapeutics | 260 | 2006-05-01 | 2012-10-31 |
| Combination Chemotherapy in Treating Patients With Hodgkin's Disease and HIV Infection bleomycin sulfate, filgrastim, Stanford V regimen - Lymphoma | Phase 2 | Unknown | Centro di Riferimento Oncologico - Aviano | 30 | 1997-05-01 | 2013-09-20 |
| Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Early-Stage Hodgkin's Disease bleomycin sulfate, Stanford V regimen, doxorubicin hydrochloride - Lymphoma | Phase 2 | Completed | Stanford University | 1995-04-01 | 2013-05-15 | |
| Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Lymphoma Bleomycin sulfate, Stanford V regimen, Doxorubicin hydrochloride - Lymphoma | Phase 2 | Completed | Stanford University | 50 | 1989-04-01 | 2020-08-12 |
| Combination Chemotherapy in Treating Children With Astrocytomas and Primitive Neuroectodermal Tumors MOPP Regimen, Leucovorin Calcium, Mechlorethamine Hydrochloride - Brain and Central Nervous System Tumors | Phase 2 | Completed | M.D. Anderson Cancer Center | 4 | 1989-02-01 | 2013-02-18 |
Hodgkin Disease (5) · Lymphoma (4) · Lymphoma, T-Cell, Cutaneous (2) · Mycosis Fungoides (2) · Astrocytoma (1) · Central Nervous System Neoplasms (1) · Dermatitis, Contact (1) · Lichen Planus (1) · Recurrence (1)
Stanford University (2) · Centro di Riferimento Oncologico - Aviano (1) · M.D. Anderson Cancer Center (1) · Mayo Clinic (1) · Memorial Sloan Kettering Cancer Center (1) · Rochester Skin Lymphoma Medical Group, PLLC (1) · St. Jude Children's Research Hospital (1) · Yaupon Therapeutics (1)
United States (8) · Italy (1)
Sandra J. Horning, MD (2) · Brian Poligone, MD, PhD (1) · Jamie Flerlage, MD (1) · Jason Sluzevich, MD (1) · Joann Ater, MD (1) · Juliet Barker, MBBS (1) · Miguel-Angel Perales, MD (1) · Stuart Lessin, M.D. (1) · Tanya Trippett, MD (1) · Umberto Tirelli, MD (1)
PMID 23069814, PMID 34091453, PMID 35122614, PMID 35536441, PMID 37802679, PMID 7537796, PMID 8836420
P30CA016672 (1)