8 completed, 3 unknown, 2 recruiting. 6 Not applicable, 2 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 5, Unknown 1 |
| Phase 4 | 2 | Completed 2 |
| Phase 3 | 1 | Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Research on the Mechanism Affecting Progression of Bronchiectasis Pseudomonas aeruginosa colonization infection, Macrolides - Bronchiectasis | Recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 150 | 2021-02-01 | 2026-01-05 | |
| Macrolides in COPD- Bronchiectasis Overlap Macrolides - Bronchiectasis | Unknown | Assiut University | 60 | 2020-08-01 | 2020-07-22 | |
| Population Pharmacokinetics of Cephalosporins and Macrolides in Chinese Children With Community Acquired Pneumonia Cephalosporins and Macrolide Antibiotics - Community Acquired Pneumonia | Unknown | Beijing Children's Hospital | 750 | 2017-06-21 | 2017-06-26 | |
| Effect of Antimicrobial Treatment of Acute Otitis Media on the Intestinal Microbiome in Children Amoxicillin, Amoxicillin-Potassium Clavulanate, Macrolide - Acute Otitis Media | Phase 4 | Completed | University of Oulu | 73 | 2016-11-01 | 2022-08-11 |
| Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia Ceftriaxone + Macrolide, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam + Macrolide - Respiratory Tract Diseases, Influenza (Pandemic) | Phase 3 | Recruiting | UMC Utrecht | 20000 | 2016-04-11 | 2026-11-04 |
| Clarithromycin as Adjuvant to Periodontal Debridement Clarithromycin, Placebo, One-stage full-mouth ultrasonic debridement (FMUD) - Aggressive Periodontitis | Not applicable | Completed | Universidade Estadual Paulista Júlio de Mesquita Filho | 40 | 2014-03-01 | 2017-11-21 |
| Macrolide Mediates Pulmonary Infection of Pseudomonas Aeruginosa Azithromycin - Bronchiectasis | Not applicable | Completed | Jin-Fu Xu | 71 | 2014-01-01 | 2016-10-14 |
| Trial for the Treatment of Acute Asthma in Wheezy Pre-school Aged Children Azithromycin, Suspension Placebo - Asthma | Not applicable | Unknown | Janielee Williamson | 440 | 2010-01-01 | 2012-07-12 |
| Monotherapy Versus Bitherapy in Non-severe Hospitalized Community-acquired Pneumonia Beta lactam (amoxicillin / clav. acid OR cefuroxime), Beta-lactam (amoxicillin / clav. acid OR cefuroxime) AND macrolide (clarithromycin) - Community-acquired Pneumonia | Phase 4 | Completed | Swiss National Fund for Scientific Research | 601 | 2009-01-01 | 2013-04-25 |
| Intravenous Erythromycin Before Endoscopy in Patients With Variceal Bleeding: A Randomized, Double-Blind Trial Erythromycin, Placebo - Variceal Bleeding | Not applicable | Completed | King Abdulaziz Medical City | 102 | 2007-01-01 | 2010-02-02 |
| Macrolide Azithromycin to Prevent Rapid Worsening of Symptoms Associated With Chronic Obstructive Pulmonary Disease Macrolide Antibiotic (Azithromycin), Placebo - Pulmonary Disease, Chronic Obstructive | Not applicable | Completed | University of Minnesota | 1142 | 2006-03-01 | 2019-11-18 |
| Selection of Antibiotic Resistance by Azithromycin and Clarithromycin in the Oral Flora Macrolides (azithromycin or clarithromycin) - Healthy Volunteers | Not applicable | Completed | Universiteit Antwerpen | 203 | 2002-07-01 | 2006-07-20 |
| Macrolide in Pregnancy and Adverse Child Outcomes Macrolides, Penicillins - Infection | Completed | Institute of Child Health | 726274 | 1990-01-01 | 2019-05-15 |
Bronchiectasis (3) · Community-Acquired Pneumonia (3) · Pneumonia (2) · Aggressive Periodontitis (1) · Asthma (1) · COVID-19 (1) · Community-Acquired Infections (1) · Infections (1) · Influenza, Human (1) · Lung Diseases (1) · Otitis Media (1) · Pseudomonas Infections (1) · Pulmonary Disease, Chronic Obstructive (1) · Respiratory Tract Diseases (1) · Respiratory Tract Infections (1)
Assiut University (1) · Beijing Children's Hospital (1) · Institute of Child Health (1) · Janielee Williamson (1) · Jin-Fu Xu (1) · King Abdulaziz Medical City (1) · Swiss National Fund for Scientific Research (1) · UMC Utrecht (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · Universidade Estadual Paulista Júlio de Mesquita Filho (1) · Universiteit Antwerpen (1) · University of Minnesota (1) · University of Oulu (1)
China (3) · Belgium (2) · Canada (2) · Finland (2) · Saudi Arabia (2) · Switzerland (2) · United States (2) · Australia (1) · Colombia (1) · Croatia (1) · Czechia (1) · Estonia (1) · France (1) · Germany (1) · Hungary (1)
A-Dong Shen, Master (1) · Arnaud Perrier, MD (1) · Bao-Ping Xu, MD (1) · Colin McArthur, Dr (1) · David W Johnson, MD (1) · Dennis E. Niewoehner, MD (1) · Derek Angus, Prof (1) · Fernando J. Martinez, MD (1) · Frank Sciurba, MD (1) · Gerard J. Criner, MD (1) · Herman Goossens, MD, PhD (1) · Ibrahim H Altraif, MBBS, FRCP (1) · Jin-Fu Xu, PhD (1) · John E. Connett, PhD (1) · John J. Reilly, MD (1)
PMID 17292768, PMID 19023036, PMID 21145052, PMID 21864166, PMID 22288485, PMID 23226013, PMID 24779680, PMID 25286173, PMID 25759571, PMID 26229455, PMID 28671507, PMID 29065885, PMID 29444682, PMID 32075790, PMID 32267771, PMID 32876697, PMID 33197289, PMID 33394942, PMID 33509275, PMID 33631065, PMID 34229290, PMID 34251506, PMID 34351721, PMID 34351722, PMID 34473343, PMID 34606578, PMID 34790237, PMID 35315874, PMID 35505308, PMID 36525245, PMID 36942550, PMID 36967714, PMID 37039790, PMID 37256341, PMID 37489818, PMID 37877585, PMID 37888913, PMID 40261382, PMID 40360262, PMID 42823695
2015 (1), 2023 (1), U10HL074424 (1)