6 completed, 2 recruiting, 2 unknown. 3 Not applicable, 3 Phase 1, 2 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 2, Recruiting 1 |
| Phase 1 | 3 | Completed 2, Recruiting 1 |
| Early Phase 1 | 2 | Completed 2 |
| Phase 2 | 1 | Unknown 1 |
Follow Limonene: new trials by email Literature Review of Limonene trials Research Report on Limonene
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Behavioral Pharmacology of Orally Administered THC and D-limonene D-Limonene, Delta-9-THC, Placebo - Subjective Drug Effects, THC | Phase 1 | Recruiting | Johns Hopkins University | 65 | 2025-02-14 | 2026-05-28 |
| Limonene for Pulmonary Nodule Chemoprevention Limonene capsule, Limonene capsules(Placebo) - Pulmonary Nodules | Phase 2 | Unknown | Shanghai Jiao Tong University School of Medicine | 160 | 2023-02-01 | 2023-02-06 |
| CYP2C19 Variants and Limonene Metabolism Limonene - CYP2C19 Genetic Variants | Not applicable | Recruiting | Stanford University | 20 | 2021-10-30 | 2024-12-16 |
| Limonene on Regulating Metabolism-related Fatty Liver Disease (MAFLD) and Analysis of TCM Constitution Limonene capsule, Limonene capsules(Placebo) - Fatty Liver | Early Phase 1 | Completed | Hongsheng Tan | 57 | 2021-02-22 | 2021-11-02 |
| A Retrospective, Real-world Study of ELP Used in the Expectorant Treatment of Community-acquired Pneumonia Eucalyptol, Limonene and Pinene Enteric Soft Capsule, Ambroxol injection, Other oral mucolytic drugs - Community-acquired Pneumonia | Unknown | Beijing Grand Johamu Pharmaceutical Company, Ltd. | 10000 | 2020-09-01 | 2021-11-26 | |
| Olfactory Odour Stimulation for Metabolism Control D-Limonene, SLVO - Obesity | Not applicable | Completed | University Hospital, Basel, Switzerland | 41 | 2019-12-10 | 2023-12-06 |
| Behavioral Pharmacology of THC and D-limonene Placebo, Vaporized THC, limonene, or THC and limonene - D-limonene and THC Pharmacodynamics | Phase 1 | Completed | Johns Hopkins University | 53 | 2019-04-01 | 2023-12-11 |
| Efficacy and Safety of a Food Supplement With Standardized Menthol, Limonene, and Gingerol Content in Patients With Irritable Bowel Syndrome Food Supplement With Standardized Menthol, Limonene, and Ginger, Placebo - Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea | Not applicable | Completed | Federal Stare Budgetary Scientific Institution, Mental Health Research Center | 56 | 2018-02-09 | 2020-07-29 |
| Human Salivary Gland Disposition of Alda-341 in Patients Undergoing Salivary Gland Surgery Alda-341 - Submandibular Gland Tumor, Parotid Gland Tumor | Early Phase 1 | Completed | Stanford University | 10 | 2016-02-01 | 2020-03-05 |
| Limonene Study in Women With Breast Cancer limonene - Breast Cancer | Phase 1 | Completed | University of Arizona | 59 | 2009-08-01 | 2017-10-27 |
Breast Neoplasms (1) · Community-Acquired Pneumonia (1) · Fatty Liver (1) · Irritable Bowel Syndrome (1) · Multiple Pulmonary Nodules (1) · Obesity (1) · Parotid Neoplasms (1) · Submandibular Gland Neoplasms (1)
Johns Hopkins University (2) · Stanford University (2) · Beijing Grand Johamu Pharmaceutical Company, Ltd. (1) · Federal Stare Budgetary Scientific Institution, Mental Health Research Center (1) · Hongsheng Tan (1) · Shanghai Jiao Tong University School of Medicine (1) · University Hospital, Basel, Switzerland (1) · University of Arizona (1)
United States (5) · China (3) · Russia (1) · Switzerland (1)
Biyun Qian, Doctor (2) · Austin Zamarripa, PhD (1) · Hongsheng Tan, Doctor (1) · Katharina Timper, Dr. med (1) · Quynh-Thu Le, MD (1) · Rong Li, Doctor (1) · Ryan Vandrey, PhD (1) · Xiaoyun Chen, Doctor (1)
2019 (1), R01DA043475 (1), R21CA123033 (1)