6 completed, 3 terminated, 2 active not recruiting, 1 unknown. 12 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 12 | Completed 6, Terminated 3, Active not recruiting 2, Unknown 1 |
| Phase 2 | 5 | Completed 3, Terminated 2 |
Follow Leuprolide Acetate: new trials by email Literature Review of Leuprolide Acetate trials Research Report on Leuprolide Acetate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer Biopsy, Bone Scan, Computed Tomography - Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 1 | Active not recruiting | Roswell Park Cancer Institute | 3 | 2024-12-19 | 2026-08-07 |
| Phase 1 Study to Evaluate the Pharmacokinetics and Safety Following SC Administration of DWJ108J in Patients With Prostate Cancer Leuprolide Acetate - Prostate Cancer | Phase 1 | Unknown | Daewoong Pharmaceutical Co. LTD. | 44 | 2017-02-01 | 2017-01-24 |
| Enzalutamide, Radiation Therapy and Hormone Therapy in Treating Patients With Intermediate or High-Risk Prostate Cancer Enzalutamide, Goserelin acetate, Leuprolide acetate - Adenocarcinoma of the Prostate, Recurrent Prostate Cancer | Phase 1 | Active not recruiting | Thomas Jefferson University | 25 | 2014-04-02 | 2025-11-25 |
| Leuprolide Acetate or Goserelin Acetate With or Without Vismodegib Followed by Surgery in Treating Patients With Locally Advanced Prostate Cancer Goserelin Acetate, Laboratory Biomarker Analysis, Leuprolide Acetate - Prostate Adenocarcinoma, Stage IIA Prostate Cancer AJCC v7 | Phase 1 / Phase 2 | Terminated | National Cancer Institute (NCI) | 10 | 2010-07-09 | 2019-02-28 |
| Everolimus, Bicalutamide, and Leuprolide Acetate in Treating Patients Undergoing Radiation Therapy For High-Risk Locally Advanced Prostate Cancer bicalutamide, everolimus, leuprolide acetate - Prostate Cancer | Phase 1 | Completed | Institut du Cancer de Montpellier - Val d'Aurelle | 30 | 2009-01-01 | 2016-05-25 |
| Safety Study of Sorafenib With Androgen Deprivation and Radiotherapy to Treat Prostate Cancer Leuprolide acetate, Bicalutamide, Sorafenib - Prostate Cancer | Phase 1 / Phase 2 | Terminated | Beth Israel Medical Center | 4 | 2008-09-01 | 2018-12-11 |
| Hormone Therapy and Temsirolimus in Treating Patients With Relapsed Prostate Cancer leuprolide acetate, goserelin acetate, bicalutamide - Adenocarcinoma of the Prostate, Recurrent Prostate Cancer | Phase 1 | Terminated | National Cancer Institute (NCI) | 24 | 2007-09-01 | 2013-01-07 |
| Docetaxel, Radiation Therapy, and Hormone Therapy in Treating Patients With Locally Advanced Prostate Cancer Bicalutamide, docetaxel, GnRh analog - Prostate Cancer | Phase 1 | Completed | Medical University of South Carolina | 20 | 2007-01-16 | 2024-01-31 |
| Docetaxel, Androgen Ablation, and External-Beam Radiation Therapy in Patients With High-Risk Localized Prostate Cancer docetaxel, leuprolide acetate, radiation therapy - Prostate Cancer | Phase 1 / Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 23 | 2005-08-01 | 2017-06-01 |
| Intensity-Modulated Radiation Therapy in Treating Patients With Stage I, Stage II, Stage III, or Stage IV Prostate Cancer goserelin acetate, leuprolide acetate, image-guided radiation therapy - Prostate Cancer | Phase 1 / Phase 2 | Completed | Mayo Clinic | 100 | 2002-03-01 | 2012-03-19 |
| SU5416 Plus Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer bicalutamide, flutamide, goserelin acetate - Prostate Cancer | Phase 1 | Completed | University of Chicago | 3 | 2001-11-01 | 2013-09-05 |
| Combination Chemotherapy in Treating Patients With Advanced Prostate Cancer carboplatin, endocrine-modulating drug therapy, estramustine phosphate sodium - Prostate Cancer | Phase 1 / Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 18 | 1998-04-01 | 2013-06-24 |
Prostatic Neoplasms (12)
National Cancer Institute (NCI) (2) · Beth Israel Medical Center (1) · Daewoong Pharmaceutical Co. LTD. (1) · Institut du Cancer de Montpellier - Val d'Aurelle (1) · Mayo Clinic (1) · Medical University of South Carolina (1) · Memorial Sloan Kettering Cancer Center (1) · Roswell Park Cancer Institute (1) · Thomas Jefferson University (1) · UNC Lineberger Comprehensive Cancer Center (1) · University of Chicago (1)
United States (9) · France (1)
Christopher Logothetis (2) · David Azria, MD, PhD (1) · David Marshall, MD (1) · Robert Den, MD (1) · Saby George, MD (1) · Seth Cohen, MD (1) · Steven E. Schild, M.D. (1) · Walter M. Stadler, MD, FACP (1) · William K. Kelly, DO (1) · Young Whang, MD, PhD (1)
N01CM00039 (1), N01CM62202 (1), P30CA015083 (1), P30CA016672 (1), U01CA062461 (1), U01CA062491 (1)