3 completed, 1 unknown. 2 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 1, Unknown 1 |
| Phase 2 | 2 | Completed 2 |
Follow interleukin-4-Pseudomonas exotoxin: new trials by email Literature Review of interleukin-4-Pseudomonas exotoxin trials Research Report on interleukin-4-Pseudomonas exotoxin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma MDNA55 - Glioblastoma, Grade IV Astrocytoma | Phase 2 | Completed | Medicenna Therapeutics, Inc. | 47 | 2017-04-11 | 2022-10-24 |
| Intravenous Interleukin-4 PE38KDEL Cytotoxin in Treating Patients With Recurrent or Metastatic Kidney Cancer, Non-Small Cell Lung Cancer, or Breast Cancer interleukin-4 PE38KDEL cytotoxin - Breast Cancer, Kidney Cancer | Phase 1 | Completed | Neurocrine Biosciences | 2002-01-01 | 2013-07-18 | |
| NBI-3001 Followed by Surgery in Treating Patients With Recurrent Glioblastoma Multiforme interleukin-4 PE38KDEL cytotoxin, conventional surgery - Brain and Central Nervous System Tumors | Phase 2 | Completed | Neurocrine Biosciences | 2001-03-01 | 2013-07-18 | |
| IL-4(38-37)-PE38KDEL Immunotoxin in Treating Patients With Recurrent Malignant Astrocytoma interleukin-4 PE38KDEL cytotoxin, isolated perfusion, surgical procedure - Brain and Central Nervous System Tumors | Phase 1 | Unknown | Barrett Cancer Center | 30 | 1999-03-01 | 2013-12-18 |
Brain Neoplasms (3) · Glioblastoma (3) · Central Nervous System Neoplasms (2) · Gliosarcoma (2) · Astrocytoma (1) · Breast Neoplasms (1) · Breast Neoplasms, Male (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Renal Cell (1) · Glioma (1) · Kidney Neoplasms (1) · Lung Neoplasms (1)
Neurocrine Biosciences (2) · Barrett Cancer Center (1) · Medicenna Therapeutics, Inc. (1)
United States (4)
Henry Pan, MD, PhD (2) · Ronald E. Warnick, MD (1)