4 completed, 3 terminated. 7 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 4, Terminated 3 |
| Phase 2 | 1 | Completed 1 |
Follow interferon gamma-1b: new trials by email Literature Review of interferon gamma-1b trials Research Report on interferon gamma-1b
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Long-Term Safety Extension Study of ACTIMMUNE® (Interferon γ-1b) in Children and Young Adults With Friedreich's Ataxia interferon γ-1b - Friedreich's Ataxia | Phase 3 | Completed | Amgen | 38 | 2016-06-28 | 2024-12-10 |
| Safety, Tolerability and Efficacy of ACTIMMUNE® Dose Escalation in Friedreich's Ataxia Study Interferon γ-1b - Friedreich's Ataxia | Phase 3 | Completed | Amgen | 86 | 2015-12-25 | 2024-12-19 |
| Safety, Tolerability and Efficacy of ACTIMMUNE® Dose Escalation in Friedreich's Ataxia Interferon γ-1b, Placebo - Friedreich's Ataxia | Phase 3 | Completed | Amgen | 92 | 2015-06-01 | 2024-12-19 |
| The INSPIRE Trial: A Study of Interferon Gamma-1b for Idiopathic Pulmonary Fibrosis (IPF) Interferon gamma-1b ("Actimmune") - Idiopathic Pulmonary Fibrosis, Lung Disease | Phase 3 | Terminated | InterMune | 826 | 2003-12-01 | 2009-07-02 |
| Immunotherapy Using Cyclosporine, Interferon Gamma, and Interleukin-2 After High-Dose Myeloablative Chemotherapy With Autologous Stem Cell Transplantation in Treating Patients With Refractory or Relapsed Hodgkin's Lymphoma aldesleukin, filgrastim, recombinant interferon gamma - Lymphoma | Phase 2 / Phase 3 | Completed | Children's Oncology Group | 24 | 2003-11-01 | 2013-10-17 |
| An Open-Label Study of the Safety of Interferon Gamma-1b in Patients With IPF Interferon gamma-1b - Idiopathic Pulmonary Fibrosis, Pulmonary Fibrosis | Phase 3 | Terminated | InterMune | 91 | 2003-11-01 | 2007-11-06 |
| Safety and Efficacy of Interferon Gamma-1b Plus Chemotherapy for Ovarian and Peritoneal Cancer Interferon gamma-1b - Ovarian Carcinoma, Peritoneal Carcinoma | Phase 3 | Terminated | InterMune | 847 | 2001-10-01 | 2007-11-01 |
Friedreich Ataxia (3) · Fibrosis (2) · Idiopathic Pulmonary Fibrosis (2) · Lung Diseases (2) · Pulmonary Fibrosis (2) · Carcinoma (1) · Hodgkin Disease (1) · Lymphoma (1) · Neoplasms (1) · Ovarian Neoplasms (1) · Recurrence (1)
Amgen (3) · InterMune (3) · Children's Oncology Group (1)
United States (7) · Australia (1) · Canada (1)
Allen R. Chen, MD, PhD, MHS (1) · Sharon L. Gardner, MD (1)
PMID 19570573, PMID 24311766, PMID 28657784, PMID 31047956, PMID 33434107, PMID 35688625, PMID 38238788