12 completed. 12 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 12 | Completed 12 |
| Phase 2 | 1 | Completed 1 |
Follow Immunotherapy: new trials by email Literature Review of Immunotherapy trials Research Report on Immunotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Stereotactic Body Radiation Therapy With Immunotherapy for the Treatment of Mesothelioma Immunotherapy, Quality-of-Life Assessment, Stereotactic Body Radiation Therapy - Pleural Mesothelial Neoplasm | Phase 1 | Completed | Mayo Clinic | 20 | 2021-07-12 | 2026-07-08 |
| Boiled Peanut Oral Immunotherapy Boiled Peanut Powder - Peanut Hypersensitivity | Phase 1 | Completed | Alton Melton | 8 | 2019-11-05 | 2024-09-19 |
| Pembrolizumab and Vorinostat Combined With Temozolomide for Newly Diagnosed Glioblastoma Pembrolizumab, Vorinostat, Temozolomide - Glioblastoma, Brain Tumor | Phase 1 | Completed | H. Lee Moffitt Cancer Center and Research Institute | 21 | 2018-03-16 | 2025-10-06 |
| Immunotherapy Study for Metastatic Renal Cell Cancer HyperAcute®-Renal (HAR) Immunotherapy - Metastatic Renal Cell Carcinoma, Metastatic Clear-cell Renal Cancer | Phase 1 | Completed | NewLink Genetics Corporation | 18 | 2015-05-01 | 2022-04-06 |
| DNX-2401 With Interferon Gamma (IFN-γ) for Recurrent Glioblastoma or Gliosarcoma Brain Tumors Single intratumoral injection of DNX-2401, Interferon-gamma - Glioblastoma or Gliosarcoma | Phase 1 | Completed | DNAtrix, Inc. | 37 | 2014-09-11 | 2018-07-16 |
| Safety and Efficacy of Listeria in Combination With Chemotherapy as Front-line Treatment for Malignant Pleural Mesothelioma Immunotherapy plus chemotherapy, Immunotherapy with cyclophosphamide plus chemotherapy - Malignant Pleural Mesothelioma | Phase 1 | Completed | Aduro Biotech, Inc. | 60 | 2014-09-03 | 2020-09-30 |
| Vaccine Combining Multiple Class I Peptides and Montanide ISA 51VG With Escalating Doses of Anti-PD-1 Antibody Nivolumab or Ipilimumab With Nivolumab For Patients With Resected Stages IIIC/ IV Melanoma NY-ESO-1 157-165 (165V), Nivolumab, gp100:280-288 (288V) - Melanoma (Skin) | Phase 1 | Completed | H. Lee Moffitt Cancer Center and Research Institute | 73 | 2010-08-13 | 2023-07-19 |
| Multiple Class I Peptides & Montanide ISA 51 VG w Escalating Doses of Anti-PD-1 ab BMS936558 MART-1, NY-ESO-1, gp100:209-217(210M) - Melanoma (Skin) | Phase 1 | Completed | H. Lee Moffitt Cancer Center and Research Institute | 127 | 2010-08-04 | 2023-01-18 |
| Pilot Study of Haploidentical Natural Killer Cell Infusions for Poor Prognosis Non-AML Hematologic Malignancies NK Cell Infusion, Immunotherapy, Miltenyi Biotec CliniMACS device - Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia | Phase 1 | Completed | St. Jude Children's Research Hospital | 48 | 2007-03-01 | 2013-07-16 |
| Immunotherapy With TG4040 in Treatment-naïve Patients Chronically Infected With Hepatitis C Virus MVA-HCV (Immunotherapy) - Hepatitis C, Chronic | Phase 1 | Completed | Transgene | 42 | 2006-12-01 | 2010-09-03 |
| Anti-pseudomonas IgY to Prevent Infections in Cystic Fibrosis Anti-pseudomonas IgY gargle - Cystic Fibrosis, Infection | Phase 1 / Phase 2 | Completed | Immunsystem AB | 14 | 2003-11-01 | 2016-09-01 |
| Gene Modified Allogeneic Neuroblastoma Cells For Treatment of Relapsed/Refractory Neuroblastoma Interleukin-2 - Neuroblastoma | Phase 1 | Completed | St. Jude Children's Research Hospital | 24 | 1998-08-01 | 2008-06-03 |
Brain Neoplasms (2) · Glioblastoma (2) · Melanoma (2) · Neoplasms (2) · Carcinoma, Renal Cell (1) · Central Nervous System Diseases (1) · Central Nervous System Neoplasms (1) · Cystic Fibrosis (1) · Glioma (1) · Gliosarcoma (1) · Hematologic Neoplasms (1) · Hepatitis C, Chronic (1) · Hypersensitivity (1) · Infections (1) · Kidney Neoplasms (1)
H. Lee Moffitt Cancer Center and Research Institute (3) · St. Jude Children's Research Hospital (2) · Aduro Biotech, Inc. (1) · Alton Melton (1) · DNAtrix, Inc. (1) · Immunsystem AB (1) · Mayo Clinic (1) · NewLink Genetics Corporation (1) · Transgene (1)
United States (10) · France (1) · Sweden (1)
Annika Hollsing, MD, PhD (1) · Frederick Lang, MD (1) · Gregory A Hale, MD (1) · Jaclyn Bjelac, MD (1) · Karen Fink, MD, PhD (1) · Nam Tran, MD, PhD (1) · Nikhil I. Khushalani, M.D. (1) · Nikhil Khushalani, M.D. (1) · Peter Forsyth, M.D. (1) · Raffit Hassan, MD (1) · Vinay Puduvalli, MBBS (1) · William G. Breen, M.D. (1) · Wing Leung, MD, PhD (1)
PMID 21699798, PMID 24145345, PMID 31263030, PMID 32043778, PMID 32671834, PMID 36450385