3 completed, 3 terminated. 5 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Terminated 3, Completed 2 |
| Phase 1 | 2 | Completed 1, Terminated 1 |
Follow icenticaftor: new trials by email Literature Review of icenticaftor trials Research Report on icenticaftor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QBW251 in Subjects With Bronchiectasis QBW251, Placebo - Bronchiectasis | Phase 2 | Terminated | Novartis Pharmaceuticals | 42 | 2021-02-02 | 2025-09-26 |
| Pharmacokinetic Study of Icenticaftor in Participants With Hepatic Impairment Icenticaftor - Hepatic Failure | Phase 1 | Completed | Novartis Pharmaceuticals | 40 | 2020-10-30 | 2024-06-20 |
| Clinical Study to Assess the Mode of Action of QBW251 in Patients With Chronic Obstructive Pulmonary Disease (COPD) QBW251, Placebo - Chronic Obstructive Pulmonary Disease | Phase 2 | Terminated | Novartis Pharmaceuticals | 54 | 2020-09-10 | 2024-06-20 |
| Dose-range Finding Efficacy and Safety Study for QBW251 in COPD Patients QBW251, Placebo, COPD maintenance background therapy - Pulmonary Disease, Chronic Obstructive | Phase 2 | Completed | Novartis Pharmaceuticals | 974 | 2019-09-12 | 2023-04-28 |
| A Safety, Tolerability and Efficacy Study With QBW251 in COPD Patients With QBW251 QBW251, Placebo - Chronic Obstructive Pulmonary Disease, COPD | Phase 2 | Completed | Novartis Pharmaceuticals | 92 | 2015-04-30 | 2021-01-05 |
| Safety, Tolerability, Pharmacokinetics, and Preliminary Pharmacodynamics of QBW251 in Healthy Subjects and Cystic Fibrosis Patients Placebo, QBW251 - Cystic Fibrosis | Phase 1 / Phase 2 | Terminated | Novartis Pharmaceuticals | 153 | 2012-07-31 | 2020-12-30 |
Pulmonary Disease, Chronic Obstructive (3) · Aspergillosis, Allergic Bronchopulmonary (1) · Bronchiectasis (1) · Bronchitis, Chronic (1) · Cystic Fibrosis (1) · Inflammation (1) · Liver Failure (1)
Germany (4) · United Kingdom (4) · United States (4) · Austria (2) · Belgium (2) · France (2) · Poland (2) · Spain (2) · Argentina (1) · Australia (1) · Canada (1) · China (1) · Colombia (1) · Czechia (1) · Denmark (1)
2018 (1)