2 completed, 1 recruiting, 1 terminated, 1 unknown. 2 Not applicable, 1 Phase 2, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Recruiting 1 |
| Phase 4 | 1 | Terminated 1 |
Follow Hypertonic saline solution: new trials by email Literature Review of Hypertonic saline solution trials Research Report on Hypertonic saline solution
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Early Continuous Infusion of HSS on the Neurological Outcome at 6 Months in TBI Patients. Hypertonic saline solution - TBI Traumatic Brain Injury | Phase 3 | Recruiting | Nantes University Hospital | 760 | 2026-04-21 | 2026-07-29 |
| Coagulation Activation by Hyperosmolar Agents in Intracranial Hypertension Mannitol, Hypertonic saline solution - Intracranial Hypertension, Cerebral Edema | Withdrawn | Neuromed IRCCS | 2020-12-03 | 2020-11-19 | ||
| Impact of Hypertonic Saline Solution on Acute Decompensated Heart Failure Hypertonic Saline Solution, Placebo - Acute Decompensated Heart Failure | Not applicable | Unknown | University of Monastir | 600 | 2018-07-01 | 2023-05-16 |
| Effects of Adding Hypertonic Saline Solutions and/or Etilefrine to Standard Diuretics Therapy in Hepatic Ascites Oral standard diuretics therapy, Hypertonic saline solution, Etilefrine - Hepatic Ascites | Phase 2 | Completed | Hala Abd EL-Tawab Ibrahim Radwan | 90 | 2017-11-30 | 2021-03-08 |
| Hypertonic Saline Resuscitation in Trauma Patients After Hemorrhage Control Sodium Chloride [3%], Sodium Chloride [0.9%] - Abdominal Injuries | Phase 4 | Terminated | Fundacion Clinica Valle del Lili | 52 | 2015-11-27 | 2020-06-11 |
| Sputum Clearance Effects of Hypertonic Saline in Non-cystic Fibrosis Bronchiectasis Hypertonic saline solution, Hyaneb solution, Isotonic saline solution - Bronchiectasis | Not applicable | Completed | Hospital Clinic of Barcelona | 24 | 2015-03-01 | 2016-11-15 |
Abdominal Injuries (1) · Ascites (1) · Brain Edema (1) · Brain Injuries, Traumatic (1) · Bronchiectasis (1) · Intracranial Hypertension (1) · Renal Insufficiency (1)
Fundacion Clinica Valle del Lili (1) · Hala Abd EL-Tawab Ibrahim Radwan (1) · Hospital Clinic of Barcelona (1) · Nantes University Hospital (1) · Neuromed IRCCS (1) · University of Monastir (1)
Colombia (1) · Egypt (1) · France (1) · Italy (1) · Spain (1) · Tunisia (1)
Eva Polverino, Dr. (1) · Fulvio Aloj, MD (1) · Gamal A Badra, professor (1) · Licia Iacoviello, MD, PhD (1) · Sahar El-Haggar, professor (1) · Semir Nouira, Professor (1)
PMID 11232182, PMID 12660656, PMID 15196097, PMID 16474108, PMID 17172977, PMID 19602136, PMID 20346637, PMID 21749847, PMID 22844565, PMID 24462960, PMID 24811138, PMID 24829672, PMID 26630543, PMID 27941973, PMID 27991854, PMID 28285098, PMID 28661458, PMID 28932357, PMID 29608812, PMID 30992841, PMID 32071136, PMID 3522371, PMID 36624448, PMID 680588