2 terminated, 1 active not recruiting, 1 recruiting, 1 withdrawn. 5 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Terminated 2, Active not recruiting 1, Recruiting 1, Withdrawn 1 |
| Phase 1 | 4 | Terminated 2, Active not recruiting 1, Withdrawn 1 |
Follow HDM201: new trials by email Literature Review of HDM201 trials Research Report on HDM201
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Siremadlin Alone and in Combination With Donor Lymphocyte Infusion in Acute Myeloid Leukemia Post-allogeneic Stem Cell Transplant Siremadlin - Acute Myeloid Leukemia, Allogeneic Stem Cell Transplantation | Phase 1 / Phase 2 | Terminated | Novartis Pharmaceuticals | 8 | 2023-02-23 | 2025-05-16 |
| HDM201 and Pazopanib in Patients With P53 Wild-type Advanced/Metastatic Soft Tissue Sarcomas Pazopanib, HDM201 - Advanced Soft-tissue Sarcoma, Metastatic Soft-tissue Sarcoma | Phase 1 / Phase 2 | Active not recruiting | Centre Leon Berard | 47 | 2022-04-15 | 2026-06-22 |
| A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors. HDM201, Ribociclib, Cabozantinib - Malignant Solid Tumor | Phase 2 | Recruiting | Centre Leon Berard | 455 | 2020-01-28 | 2026-07-08 |
| HDM201 Added to CT in R/R or Newly Diagnosed AML HDM201, cytarabine, anthracycline - Leukemia, Myeloid, Acute | Phase 1 / Phase 2 | Withdrawn | Novartis Pharmaceuticals | 2019-11-15 | 2020-01-09 | |
| Platform Study of Novel Ruxolitinib Combinations in Myelofibrosis Patients Ruxolitinib, Siremadlin, Crizanlizumab - Myelofibrosis | Phase 1 / Phase 2 | Terminated | Novartis Pharmaceuticals | 45 | 2019-09-26 | 2025-08-07 |
Leukemia, Myeloid, Acute (2) · Neoplasm Metastasis (1) · Neoplasm, Residual (1) · Primary Myelofibrosis (1) · Sarcoma (1)
Novartis Pharmaceuticals (3) · Centre Leon Berard (2)
France (2) · Germany (2) · Italy (2) · Spain (2) · Australia (1) · Canada (1) · Denmark (1) · Hungary (1) · Netherlands (1) · Russia (1) · Sweden (1) · Switzerland (1) · Turkey (Türkiye) (1) · United Kingdom (1)
2019 (2), 2018 (1), 2023 (1)