48 completed, 14 active not recruiting, 12 terminated, 9 unknown. 41 Phase 2, 36 Phase 3, 10 Phase 1, 5 Not applicable, 2 Phase 4.
Follow Goserelin Acetate: new trials by email Literature Review of Goserelin Acetate trials Research Report on Goserelin Acetate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Alternative Site Goserelin Acetate Injection for Ovarian Function Suppression (OFS) in Local and Locally Advanced Premenopausal Hormone Receptor Positive Breast Cancer Patients Biospecimen Collection, Goserelin Acetate, Questionnaire Administration - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Phase 2 | Recruiting | Mayo Clinic | 98 | 2026-05-22 | 2026-10-01 |
| Enhanced Systemic Combined With Local Treatment for Primary and Metastatic Lesions in Oligo-metastatic Prostate Cancer Leuprolide acetate, Goserelin acetate, Triptorelin acetate - Prostate Cancer | Phase 2 | Unknown | Fudan University | 160 | 2022-04-01 | 2022-03-16 |
| A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With Metastatic Prostate Cancer That Has Become Resistant To Testosterone-Deprivation Therapy Enzalutamide, Rucaparib camsylate, Placebo - Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma | Phase 3 | Active not recruiting | Alliance for Clinical Trials in Oncology | 61 | 2021-10-14 | 2026-02-05 |
| Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer Abiraterone Acetate, Bicalutamide, Degarelix - Castration-Sensitive Prostate Carcinoma, Metastatic Prostate Adenocarcinoma | Phase 2 | Recruiting | City of Hope Medical Center | 70 | 2021-05-04 | 2026-01-28 |
| Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With High-Risk Prostate Cancer, The ERADICATE Study Darolutamide, Goserelin Acetate, Leuprolide Acetate - Prostate Carcinoma | Phase 3 | Active not recruiting | ECOG-ACRIN Cancer Research Group | 27 | 2021-03-01 | 2026-07-28 |
| Pharmacodynamic Study Goserelin 3.6mg Injection Administered Subcutaneously in Premenopausal Patients with Breast Cancer Goserelin acetate 3.6 mg Injection, ZOLADEX® 3.6mg Injection - Breast Cancer | Phase 3 | Terminated | Eurofarma Laboratorios S.A. | 6 | 2020-10-30 | 2025-02-17 |
| Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging 3-Dimensional Conformal Radiation Therapy, Apalutamide, Computed Tomography - Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 3 | Recruiting | ECOG-ACRIN Cancer Research Group | 804 | 2020-10-08 | 2026-08-19 |
| Nivolumab + Docetaxel + ADT in mHSPC Patients With DDRD or Inflamed Tumors Androgen Deprivation Therapy, Nivolumab, Docetaxel - Hormone Sensitive Prostate Cancer, Prostate Adenocarcinoma | Phase 2 | Active not recruiting | Xiao X. Wei, MD | 47 | 2020-05-11 | 2026-08-12 |
| Androgen Deprivation Therapy on Bone Mineral Density Change in Prostate Cancer Patients Leuprorelin, Goserelin, Triptorelin - Prostatic Neoplasms | Phase 4 | Unknown | Wonju Severance Christian Hospital | 164 | 2020-01-23 | 2021-07-29 |
| BMD Alterations and Bone and Muscle Parameters During Menstrual Cessation With GnRH Goserelin Acetate - Endometriosis, Bone Density | Completed | 424 General Military Hospital | 41 | 2019-10-01 | 2021-01-12 | |
| Androgen Deprivation Therapy (ADT) and Pembrolizumab for Advanced Stage Androgen Receptor-positive Salivary Gland Carcinoma Goserelin Acetate, Pembrolizumab - Salivary Gland Carcinoma | Phase 2 | Active not recruiting | Manish Patel | 20 | 2019-05-30 | 2026-07-10 |
| A Study of Salvage Radiotherapy With or Without Enzalutamide in Recurrent Prostate Cancer Following Surgery Radiation Therapy, Enzalutamide, Bicalutamide - Prostate Cancer | Phase 2 | Active not recruiting | RTOG Foundation, Inc. | 188 | 2019-04-15 | 2025-12-30 |
| Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer Abiraterone, Bicalutamide, Degarelix - Castration Levels of Testosterone, Metastatic Prostatic Adenocarcinoma | Phase 3 | Recruiting | SWOG Cancer Research Network | 1273 | 2018-09-24 | 2026-10-08 |
| Radium Ra 223 Dichloride, Hormone Therapy and Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Prostate Cancer Leuprolide Acetate, Goserelin Acetate, Stereotactic Body Radiation Therapy - Prostate Adenocarcinoma | Phase 2 | Active not recruiting | City of Hope Medical Center | 25 | 2018-08-29 | 2026-04-09 |
| Risk and Clinical Benefit of Chemotherapy and Intensive Endocrine Therapy for Luminal B1 Early-stage Breast Cancer Epirubicin, Cyclophosphamide, Docetaxel - Breast Cancer, Chemotherapy | Phase 2 / Phase 3 | Unknown | Zhiyong Yu | 200 | 2017-12-20 | 2017-12-18 |
| Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery Bicalutamide, Degarelix, Docetaxel - Stage I Prostate Adenocarcinoma AJCC v7, Stage II Prostate Adenocarcinoma AJCC v7 | Phase 2 / Phase 3 | Active not recruiting | NRG Oncology | 612 | 2017-04-05 | 2026-09-14 |
| Pilot Study to Evaluate the Effects of a Generic Goserelin Acetate in Patients With Prostate Cancer Goserelin Acetate - Prostate Cancer | Early Phase 1 | Completed | CMX Research | 11 | 2017-02-21 | 2021-05-10 |
| Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score FACT-B, Goserelin, Anastrozole - Breast Cancer, Cancer of Breast | Phase 2 | Recruiting | Washington University School of Medicine | 50 | 2017-01-17 | 2026-07-27 |
| Management of Castration-Resistant Prostate Cancer with Oligometastases Leuprolide Acetate, Goserelin Acetate, Triptorelin - Castration-resistant Prostate Cancer Patients with Oligometastases | Phase 2 / Phase 3 | Active not recruiting | Sir Mortimer B. Davis - Jewish General Hospital | 102 | 2016-10-01 | 2024-12-04 |
| Reproductive Outcome of EM Treated by GnRH-a Associated With Laparoscopy Goserelin Acetate - Infertility Associated With Endometriosis | Not applicable | Unknown | Peking University People's Hospital | 1184 | 2016-05-01 | 2016-05-20 |
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Prostatic Neoplasms (53) · Breast Neoplasms (24) · Breast Neoplasms, Male (4) · Endometriosis (2) · Infertility (2) · Neoplasm Metastasis (2) · Neoplasms (2) · Breast Diseases (1) · Carcinoma, Ovarian Epithelial (1) · Fallopian Tube Neoplasms (1) · Hypogonadism (1) · Inflammatory Breast Neoplasms (1) · Lymphatic Metastasis (1) · Ovarian Neoplasms (1) · Recurrence (1)
National Cancer Institute (NCI) (10) · SWOG Cancer Research Network (5) · M.D. Anderson Cancer Center (4) · Mayo Clinic (4) · UNICANCER (4) · AstraZeneca (3) · City of Hope Medical Center (3) · European Organisation for Research and Treatment of Cancer - EORTC (3) · Memorial Sloan Kettering Cancer Center (3) · Radiation Therapy Oncology Group (3) · Alliance for Clinical Trials in Oncology (2) · ECOG-ACRIN Cancer Research Group (2) · Ferring Pharmaceuticals (2) · Fudan University (2) · Institute of Cancer Research, United Kingdom (2)
United States (54) · Canada (13) · United Kingdom (9) · Belgium (5) · Czechia (5) · France (5) · Germany (5) · Hungary (3) · Mexico (3) · Netherlands (3) · Poland (3) · Puerto Rico (3) · Ukraine (3) · China (2) · Finland (2)
Christopher Logothetis (3) · George Wilding, MD (2) · Michel Bolla, MD (2) · A. O. Sartor, MD (1) · Abdul-Rahman Jazieh, MD, MPH (1) · Abraham Alexander, MD (1) · Alicia K Morgans (1) · Andrew Loblaw, MD (1) · Ann H. Partridge, MD, MPH (1) · Anne Hamilton, MD, FRACP (1) · Anthony Howell, MD (1) · Arpit Rao, MD (1) · Athanasios Anastasilakis, PhD (1)
PMID 38320143, PMID 38421243, PMID 25592642, PMID 36596347, PMID 10663329, PMID 12126818, PMID 12160582, PMID 12743142, PMID 14581419, PMID 15169799, PMID 15251156, PMID 16323171, PMID 16921051, PMID 16979837, PMID 17011443, PMID 17405995, PMID 17405996, PMID 17498886, PMID 17531401, PMID 17575222, PMID 17634487, PMID 17689883, PMID 17881290, PMID 17918264, PMID 18243498, PMID 18314175, PMID 18413638, PMID 18779620, PMID 19012911, PMID 19211454, PMID 19470936, PMID 19682889, PMID 19706804, PMID 20818327, PMID 20933466, PMID 21751904, PMID 22006050, PMID 22119204, PMID 22747660, PMID 23306100, PMID 23550669, PMID 24024838, PMID 24210084, PMID 25087673, PMID 25738668, PMID 25847934, PMID 26028518, PMID 26621118, PMID 26720308, PMID 26901812
P30CA015083 (4), U10CA032102 (3), U10CA180820 (3), 2008 (2), P30CA008748 (2), P30CA033572 (2), U10CA021115 (2), U10CA180868 (2), N01CM00039 (1), N01CM00071 (1), N01CM00099 (1), N01CM00100 (1), N01CM62201 (1), N01CM62202 (1), N01CM62205 (1)