11 completed. 4 Phase 3, 3 Phase 2, 3 Phase 4, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Completed 4 |
| Phase 2 | 3 | Completed 3 |
| Phase 4 | 3 | Completed 3 |
| Phase 1 | 2 | Completed 2 |
Follow Glycopyrronium Bromide: new trials by email Literature Review of Glycopyrronium Bromide trials Research Report on Glycopyrronium Bromide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Thorough QT (TQT) Study of CHF5993 pMDI in Healthy Volunteers (HV) CHF5993, CHF5259, Moxifloxacin 400mg - Asthma, Chronic Obstructive Pulmonary Disease (COPD) | Phase 1 | Completed | Chiesi Farmaceutici S.p.A. | 95 | 2023-03-29 | 2024-09-04 |
| A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD Beclomethasone Dipropionate, Glycopyrronium Bromide, Formoterol Fumarate - COPD, COPD Exacerbation | Phase 3 | Completed | Chiesi Farmaceutici S.p.A. | 3406 | 2022-04-27 | 2026-09-21 |
| Effect of Glycopyrrolate on Vasopressors Requirement for Non-elective Caesarean Section Under Spinal Anaesthesia Glycopyrrolate 0.2 MG/ML, Normal saline - Glycopyrrolate, Post-spinal Hypotension | Phase 4 | Completed | Rajesh Deshar | 258 | 2020-06-01 | 2021-02-21 |
| Clozapine-induced Hypersalivation - Feasibility Trial Hyoscine, Glycopyrrolate, Placebo - Sialorrhea | Phase 1 / Phase 2 | Completed | Mersey Care NHS Trust | 29 | 2016-01-25 | 2018-02-28 |
| Acute Effect of Aclidinium on Hyperinflation and Ventilation Inhomogeneity in Severe COPD Patients Aclidinium Bromide, Glycopyrronium Bromide - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | University of Milan | 37 | 2014-06-01 | 2014-10-29 |
| Study to Evaluate the Efficacy and Safety of Glycopyrronium or Indacaterol Maleate and Glycopyrronium Bromide Fixed-dose Combination Regarding Symptoms and Health Status in Patients With Moderate COPD Switching From Treatment With Any Standard COPD Regimen Glycopyrronium, SABA, LABA - COPD | Phase 4 | Completed | Novartis Pharmaceuticals | 4389 | 2014-02-14 | 2019-03-19 |
| Dose Ranging Study of Glycopyrronium Bromide in Patients With Moderate or Severe Chronic Obstructive Pulmonary Disease glycopyrronium bromide - Chronic Obstructive Pulmonary Disease | Phase 2 | Completed | Prosonix Limited | 37 | 2013-05-01 | 2016-03-30 |
| Efficacy, Safety and Tolerability of the Co-administration of NVA237 Plus Indacaterol Once Daily Versus Indacaterol Once Daily in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) NVA237 50 µg and indacaterol 150 µg, Placebo to NVA237 and indacaterol 150 µg - Chronic Obstructive Pulmonary Disease (COPD) | Phase 3 | Completed | Novartis Pharmaceuticals | 449 | 2012-05-01 | 2014-11-14 |
| A Study to Assess the Safety, Tolerability and Efficacy of NVA237 Versus Placebo Glycopyrronium bromide, Placebo - Chronic Obstructive Pulmonary Disease | Phase 3 | Completed | Novartis | 1324 | 2009-10-01 | 2012-04-12 |
| 1-year Study to Assess the Efficacy, Safety, and Tolerability of Glycopyrronium Bromide (NVA237) in Chronic Obstructive Pulmonary Disease (COPD) Glycopyrronium bromide, Placebo to glycopyrronium bromide, Tiotropium - Chronic Obstructive Pulmonary Disease | Phase 3 | Completed | Novartis | 1066 | 2009-06-01 | 2012-08-17 |
| Safety and Tolerability of 28 Days Treatment With Glycopyrronium Bromide (NVA237) (100 or 200 µg Once a Day) in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease NVA237 100 µg, Placebo, NVA237 200 µg - Chronic Obstructive Pulmonary Disease (COPD) | Phase 2 | Completed | Novartis | 281 | 2007-08-01 | 2012-05-21 |
Pulmonary Disease, Chronic Obstructive (9) · Asthma (1) · Hypotension (1) · Schizophrenia, Treatment-Resistant (1) · Sialorrhea (1)
Novartis (3) · Chiesi Farmaceutici S.p.A. (2) · Novartis Pharmaceuticals (2) · Mersey Care NHS Trust (1) · Prosonix Limited (1) · Rajesh Deshar (1) · University of Milan (1)
United States (5) · Hungary (4) · Russia (4) · Spain (4) · United Kingdom (4) · Canada (3) · France (3) · Germany (3) · Italy (3) · Netherlands (3) · Poland (3) · Romania (3) · Turkey (Türkiye) (3) · Argentina (2) · Belgium (2)
Dave Singh, MA MD MRCP (1) · Geoff Down, MB BS FFPM (1) · Inti Qurashi, MBChB (1) · Pierachille Santus, MD, PhD (1) · Ronald Goldwater, MDCM/M.SC(A) (1) · Thomas Siler, MD (1)
PMID 24156566, PMID 10365009, PMID 11573596, PMID 17054153, PMID 18389982, PMID 19218369, PMID 19859776, PMID 20416390, PMID 20495139, PMID 21632228, PMID 22151296, PMID 22323952, PMID 22459983, PMID 22780437, PMID 23060624, PMID 2400072, PMID 24347351, PMID 24596459, PMID 25501602, PMID 26549785, PMID 26991619, PMID 27871302, PMID 28255987, PMID 28598894, PMID 28704246, PMID 28720132, PMID 28759487, PMID 29713156, PMID 30738019, PMID 30905688, PMID 31236286, PMID 36284288, PMID 6660460, PMID 7465128, PMID 7556827, PMID 8130043
2008 (1), 2009 (1), 2023 (1)