11 completed, 1 terminated. 9 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 8, Terminated 1 |
| Phase 1 | 4 | Completed 4 |
Follow gemcabene: new trials by email Literature Review of gemcabene trials Research Report on gemcabene
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Gemcabene for the Treatment of Pediatric NAFLD Gemcabene - Non-Alcoholic Fatty Liver Disease | Phase 2 | Terminated | Emory University | 6 | 2018-03-29 | 2020-12-31 |
| Study of Gemcabene in Adults With FPLD 300mg Gemcabene, 600mg Gemcabene - Familial Partial Lipodystrophy, Hypertriglyceridemia | Phase 1 / Phase 2 | Completed | Elif Oral | 5 | 2018-03-13 | 2020-08-17 |
| A 12-Week Study to Assess the Efficacy Safety and Tolerability of Gemcabene in Subjects With Severe Hypertriglyceridemia Gemcabene, Placebo - Severe Hypertriglyceridemia, Mixed Dyslipidaemia | Phase 2 | Completed | NeuroBo Pharmaceuticals Inc. | 91 | 2016-12-01 | 2020-06-25 |
| A 12-Week, Phase 2 Study of Gemcabene in Hypercholesterolemia Patients on Stable Moderate and High-Intensity Statins Gemcabene, Placebo - Hypercholesteremia | Phase 2 | Completed | NeuroBo Pharmaceuticals Inc. | 105 | 2016-11-01 | 2020-06-25 |
| Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable, Lipid-Lowering Therapy (COBALT-1) Gemcabene - Hypercholesteremia | Phase 2 | Completed | NeuroBo Pharmaceuticals Inc. | 8 | 2016-06-01 | 2020-06-25 |
| Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients as Monotherapy or in Combination With Atorvastatin Gemcabene, Atorvastatin, Placebo - Hypercholesterolemia | Phase 2 | Completed | NeuroBo Pharmaceuticals Inc. | 277 | 2003-01-01 | 2020-04-09 |
| Effect of Gemcabene on the Pharmacokinetics of Atorvastatin in Healthy Volunteers Gemcabene 300 mg, Gemcabene 900 mg, Atorvastatin - Hypercholesteremia | Phase 1 | Completed | NeuroBo Pharmaceuticals Inc. | 20 | 2002-11-01 | 2020-04-09 |
| The Effect of Gemcabene on Insulin Sensitivity in Nondiabetic Subjects Gemcabene 900 mg, Placebo - Insulin Sensitivity | Phase 2 | Completed | NeuroBo Pharmaceuticals Inc. | 53 | 2001-07-01 | 2020-04-09 |
| Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients on Stable Statin Therapy Gemcabene, Placebo - Hypercholesterolemia | Phase 2 | Completed | NeuroBo Pharmaceuticals Inc. | 66 | 2000-08-01 | 2020-04-09 |
| Effect of Gemcabene on the Pharmacokinetics of Simvastatin in Healthy Volunteers Gemcabene 900 mg, Simvastatin 80 mg - Hypercholesterolemia | Phase 1 | Completed | NeuroBo Pharmaceuticals Inc. | 20 | 2000-05-01 | 2020-04-09 |
| Efficacy and Safety of Gemcabene in Patients With Low HDL-C and Either Normal or Elevated Triglycerides Gemcabene 150 mg, Gemcabene 300 mg, Gemcabene 600 mg - Hypercholesterolemia, Hypertriglyceridemia | Phase 2 | Completed | NeuroBo Pharmaceuticals Inc. | 161 | 1999-12-01 | 2020-04-09 |
| Pharmacokinetics and Pharmacodynamics Study of Gemcabene in Healthy Volunteers Gemcabene 50 mg, Gemcabene 150 mg, Gemcabene 450 mg - Hypercholesterolemia | Phase 1 | Completed | NeuroBo Pharmaceuticals Inc. | 50 | 1999-04-01 | 2020-04-09 |
Hypercholesterolemia (8) · Hypertriglyceridemia (3) · Non-alcoholic Fatty Liver Disease (2) · Fatty Liver (1) · Insulin Resistance (1) · Lipodystrophy, Familial Partial (1) · Liver Diseases (1) · Obesity (1)
NeuroBo Pharmaceuticals Inc. (10) · Elif Oral (1) · Emory University (1)
United States (5) · Canada (2) · Israel (1)
Elif A Oral, M.D. (1) · Lee Golden, MD (1) · Miriam B Vos, MD (1)