3 completed, 3 withdrawn, 1 recruiting. 3 Phase 2, 2 Phase 1, 2 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Withdrawn 2, Recruiting 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 4 | 2 | Completed 1, Withdrawn 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Fresh Frozen Plasma (FFP): new trials by email Literature Review of Fresh Frozen Plasma (FFP) trials Research Report on Fresh Frozen Plasma (FFP)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| FFP In Traumatic BRAin INjury (FIT-BRAIN) Trial Fresh Frozen Plasma (FFP) - Moderate to Severe Traumatic Brain Injury | Phase 2 / Phase 3 | Recruiting | Northwestern University | 357 | 2026-02-01 | 2026-02-11 |
| Clinical Trial Assessing Non-Inferiority of Freeze Dried Plasma to Fresh Frozen Plasma in Reversing Warfarin Fresh Frozen Plasma (FFP), Freeze Dried Plasma (FDP) - Anticoagulant Reversal | Phase 2 | Withdrawn | Teleflex | 2021-05-01 | 2026-04-02 | |
| Convalescent Plasma Therapy - Zurich Protocol Convalescent plasma - COVID-19 | Phase 1 | Completed | University of Zurich | 30 | 2020-04-29 | 2021-05-03 |
| Fresh Frozen Plasma as a Substitute for Albumin in Patients Receiving a Large Volume Paracentesis Fresh Frozen Plasma (FFP), Albumin, Large Volume Paracentesis (LVP) - Liver Cirrhosis, Ascites Hepatic | Phase 2 | Withdrawn | Montefiore Medical Center | 2019-11-11 | 2022-08-25 | |
| Fresh Frozen Plasma as a Substitute for Albumin in Patients Receiving a Large Volume Paracentesis Fresh Frozen Plasma (FFP), Albumin - Liver Cirrhosis, Ascites Hepatic | Phase 4 | Withdrawn | Montefiore Medical Center | 2017-12-01 | 2019-06-14 | |
| Ascending Doses of Autologous FDP vs FFP Autologous Freeze Dried Plasma (FDP), Fresh Frozen Plasma (FFP) - Freeze Dried Plasma in Healthy Volunteers | Phase 1 | Completed | U.S. Army Medical Research and Development Command | 30 | 2017-02-13 | 2021-02-12 |
| PCC vs. FFP for Post Cardiopulmonary Bypass Coagulopathy and Bleeding Prothrombin complex concentrate (Human), Fresh frozen plasma (FFP) - Bleeding, Blood Loss, Surgical | Phase 4 | Completed | Mayo Clinic | 106 | 2016-08-01 | 2022-06-07 |
Liver Cirrhosis (2) · Blood Loss, Surgical (1) · Brain Injuries, Traumatic (1) · COVID-19 (1) · Hemorrhage (1)
Montefiore Medical Center (2) · Mayo Clinic (1) · Northwestern University (1) · Teleflex (1) · U.S. Army Medical Research and Development Command (1) · University of Zurich (1)
United States (4) · Switzerland (1)
Samuel Sigal, MD (2) · Gregory Nuttall, MD (1) · Hasan Alam, MD (1) · Jose A Cancelas, MD, PhD (1) · Markus Manz, Professor (1)
PMID 35482408, PMID 35767271, PMID 36408876, PMID 39633218, PMID 39733294
2019 (1)