15 completed. 15 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 15 | Completed 15 |
| Phase 3 | 1 | Completed 1 |
Follow Flutamide: new trials by email Literature Review of Flutamide trials Research Report on Flutamide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Study of Alternative Antiandrogen (AA) Therapy and Early Initiating of Enzalutamide for Castration-resistant Prostate Cancer (CRPC) After Combined Androgen Blockade (CAB) Therapy. Enzalutamide, Flutamide - Castration-resistant Prostate Cancer | Phase 2 | Completed | Taro Iguchi, MD, PHD | 104 | 2014-12-01 | 2021-09-16 |
| Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS Women Flutamide, Placebo - Polycystic Ovary Syndrome (PCOS) | Phase 2 | Completed | University of California, Los Angeles | 23 | 2013-04-01 | 2025-01-10 |
| Radiation Therapy, Androgen Suppression, and Docetaxel in Treating Patients With High-Risk Prostate Cancer Who Have Undergone Radical Prostatectomy bicalutamide, docetaxel, flutamide - Prostate Cancer | Phase 2 | Completed | Radiation Therapy Oncology Group | 80 | 2008-04-01 | 2019-04-24 |
| Vaccine Therapy With PROSTVAC/TRICOM and Flutamide Versus Flutamide Alone to Treat Prostate Cancer Sargramostim (GM-CSF, Leukine), Flutamide (Eulexin), PROSTVAC-F/ TRICOM - Prostate Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 64 | 2007-02-23 | 2018-11-29 |
| Effect of Flutamide on Biomarkers in Blood and Tissue Samples From Patients at High Risk of Ovarian Cancer flutamide - Ovarian Cancer | Phase 2 | Completed | University of Arizona | 127 | 2005-01-01 | 2018-07-24 |
| Hormone Therapy and Ipilimumab in Treating Patients With Advanced Prostate Cancer Bicalutamide, Flutamide, Goserelin Acetate - Prostate Adenocarcinoma, Prostate Carcinoma | Phase 2 | Completed | Mayo Clinic | 112 | 2004-06-01 | 2017-05-15 |
| Finasteride and Flutamide in Pre-surgical Trial in Prostate Cancer. Flutamide, Finasteride, Placebo - Prostate Cancer, Prostatic Intraepithelial Neoplasia | Phase 2 / Phase 3 | Completed | Ente Ospedaliero Ospedali Galliera | 125 | 2004-01-01 | 2024-09-19 |
| Exisulind and Intermittent Androgen Suppression (ADT) in Biochemical Relapsed Prostate Cancer Exisulind, luteinizing hormone-releasing hormone (LHRH) agonist, Antiandrogen - Prostate Cancer | Phase 2 | Completed | University of Washington | 32 | 2002-03-12 | 2018-08-07 |
| S0032, Combination Chemotherapy Plus Hormone Therapy in Treating Patients With Metastatic Prostate Cancer bicalutamide, estramustine, etoposide - Prostate Cancer | Phase 2 | Completed | SWOG Cancer Research Network | 41 | 2001-12-01 | 2013-07-16 |
| Flutamide In the Prevention of Prostate Cancer in Patients With Neoplasia of the Prostate flutamide, placebo - Prostate Cancer | Phase 2 | Completed | Alliance for Clinical Trials in Oncology | 63 | 2000-08-01 | 2016-07-13 |
| Hormone Therapy in Treating Patients With Prostate Cancer finasteride, flutamide, quality-of-life assessment - Prostate Cancer, Sexual Dysfunction and Infertility | Phase 2 | Completed | Alliance for Clinical Trials in Oncology | 101 | 1998-05-01 | 2016-07-04 |
| Hormone Therapy Plus Radiation Therapy in Treating Patients With Prostate Cancer flutamide, leuprolide acetate, radiation therapy - Prostate Cancer | Phase 2 | Completed | Herbert Irving Comprehensive Cancer Center | 105 | 1997-05-01 | 2014-01-06 |
| Radiation Therapy With Androgen Suppression in Treating Patients With Prostate Cancer flutamide, goserelin, leuprolide acetate - Prostate Cancer | Phase 2 | Completed | Alliance for Clinical Trials in Oncology | 180 | 1997-05-01 | 2023-08-18 |
| Effects of IAS in Men With Localized Biochemical Relapsed Prostate Cancer Flutamide, Leuprolide Acetate - Prostate Cancer | Phase 2 | Completed | University of Washington | 102 | 1997-01-08 | 2018-08-07 |
| Intermittent Hormonal Therapy With Leuprorelin and Flutamide in the Treatment of Stage D2 or TxNxM1b,c Leuprorelin, Flutamide - Prostatic Neoplasms | Phase 2 | Completed | Takeda | 341 | 1996-12-01 | 2015-07-29 |
Prostatic Neoplasms (12) · Amenorrhea (1) · Anovulation (1) · Carcinoma, Ovarian Epithelial (1) · Hirsutism (1) · Hyperandrogenism (1) · Infertility (1) · Oligomenorrhea (1) · Ovarian Neoplasms (1) · Polycystic Ovary Syndrome (1) · Prostatic Intraepithelial Neoplasia (1) · Sexual Dysfunction, Physiological (1)
Alliance for Clinical Trials in Oncology (3) · University of Washington (2) · Ente Ospedaliero Ospedali Galliera (1) · Herbert Irving Comprehensive Cancer Center (1) · Mayo Clinic (1) · National Cancer Institute (NCI) (1) · Radiation Therapy Oncology Group (1) · SWOG Cancer Research Network (1) · Takeda (1) · Taro Iguchi, MD, PHD (1) · University of Arizona (1) · University of California, Los Angeles (1)
United States (12) · Canada (2) · Italy (1) · Japan (1)
Celestia Higano, MD (2) · Andrea De Censi, MD (1) · Anthony V. D'Amico, MD, PhD (1) · Daniel Dumesic, MD (1) · David C. Smith, MD (1) · Eugene Kwon (1) · Joel Picus, MD (1) · Mark Hurwitz, MD (1) · Oliver Sartor, MD (1) · Ravi A Madan, M.D. (1) · Ronald D. Ennis, MD (1) · Setsuko K. Chambers, MD (1) · Steven R. Alberts, MD (1) · Ying Xiao, PhD (1)
PMID 17194907, PMID 18037582, PMID 18291508, PMID 24950779, PMID 25242417, PMID 31564004, PMID 36400597, PMID 37134294
U10CA031946 (2), P30CA015083 (1), P30CA023074 (1), U10CA032102 (1)