9 completed, 8 terminated, 3 withdrawn. 12 Phase 1, 7 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 12 | Completed 8, Terminated 3, Withdrawn 1 |
| Phase 2 | 7 | Completed 3, Terminated 3, Withdrawn 1 |
| Phase 3 | 3 | Terminated 2, Withdrawn 1 |
Follow figitumumab: new trials by email Literature Review of figitumumab trials Research Report on figitumumab
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study Of The Effect Of CP-751,871 In Combination With Gemcitabine And Cisplatin In Patients With Advanced Non-Small Cell Lung Cancer CP-751,871, Cisplatin, Gemcitabine - Carcinoma, Non-Small-Cell Lung | Phase 3 | Withdrawn | Pfizer | 2010-07-01 | 2014-06-17 | |
| A Study Of Cisplatin (Or Carboplatin) And Etoposide With Or Without Figitumumab (CP-751,871) In Patients With Extensive-Stage Small Cell Lung Cancer figitumumab, Cisplatin (Or Carboplatin), Etoposide - Small Cell Lung Carcinoma | Phase 2 | Terminated | Pfizer | 9 | 2010-04-01 | 2013-02-25 |
| Figitumumab Combined With Pegvisomant For Advanced Solid Tumors figitumumab, pegvisomant - Colorectal Neoplasms, Lung Neoplasms | Phase 1 | Terminated | Pfizer | 24 | 2009-11-01 | 2013-12-13 |
| A Pharmacokinetic And QT Study Of CP-751,871 In Healthy Subjects CP-751,871, CP-751,871, moxifloxacin, saline - Healthy Volunteers | Phase 1 | Terminated | Pfizer | 28 | 2009-07-01 | 2013-05-07 |
| RAD001 in Combination With CP-751,871 in Patients Wtih Advanced Sarcomas and Other Malignant Neoplasms RAD001, CP-751,871 - Sarcoma, Solid Tumor | Phase 1 | Completed | Suzanne George, MD | 21 | 2009-07-01 | 2013-11-14 |
| Phase 2 Trial Of CP-751,871 And Docetaxel In Advanced Breast Cancer CP-751,871, Docetaxel - Breast Cancer | Phase 2 | Withdrawn | Pfizer | 2009-04-01 | 2015-05-04 | |
| A Study of CP-751,871 in Patients With Recurrent Squamous Head and Neck Carcinoma CP-751,871 - Head and Neck Cancer | Phase 2 | Terminated | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 37 | 2009-01-01 | 2016-04-20 |
| Study Of CP-751,871 In Combination With Sunitinib In Patients With Advanced Solid Tumors CP-751,871, Sunitinib - Advanced Cancer, Advanced Solid Tumors | Phase 1 | Terminated | Pfizer | 45 | 2008-09-01 | 2014-06-09 |
| Trial Of CP-751, 871 And Erlotinib In Refractory Lung Cancer CP 751,871 (Figitumumab), Erlotinib - Carcinoma, Large Cell, Carcinoma, Non-Small-Cell Lung | Phase 3 | Terminated | Pfizer | 583 | 2008-05-01 | 2013-07-24 |
| Carboplatin And Paclitaxel With Or Without CP-751, 871 (An IGF-1R Inhibitor) For Advanced NSCLC Of Squamous, Large Cell And Adenosquamous Carcinoma Histology CP-751,871 (Figitumumab), Carboplatin, Paclitaxel - Carcinoma, Squamous Cell, Carcinoma, Adenosquamous | Phase 3 | Terminated | Pfizer | 681 | 2008-04-01 | 2014-01-13 |
| Study Of CP-751,871 In Patients With Ewing's Sarcoma Family Of Tumors CP-751,871 - Ewing's Sarcoma Family of Tumors | Phase 1 / Phase 2 | Completed | Pfizer | 138 | 2008-03-01 | 2015-10-28 |
| Study of CP-751,871 in Combination With Carboplatin and Paclitaxel in Advanced Lung Cancer CP-751,871 + carboplatin + paclitaxel - Carcinoma, Non-Small-Cell Lung | Phase 1 | Completed | Pfizer | 19 | 2008-01-01 | 2013-04-11 |
| Study Of CP-751,871 In Combination With Cisplatin And Gemcitabine In Chemotherapy-Naïve Patients With Advanced Non-Small Cell Lung Cancer CP-751,871, Cisplatin, Gemcitabine - Carcinoma, Non-Small-Cell Lung | Phase 1 | Completed | Pfizer | 46 | 2007-11-01 | 2013-03-21 |
| Study Of CP-751,871 In Combination With Exemestane In Postmenopausal Women With Hormone Receptor Positive Advanced Breast Cancer CP-751,871, exemestane, Fulvestrant - Breast Neoplasms | Phase 2 | Terminated | Pfizer | 219 | 2007-02-01 | 2015-10-28 |
| Study of CP-751,871 in Combination With Docetaxel and Prednisone in Patients With Hormone Insensitive Prostate Cancer (HRPC) CP-751,871, docetaxel, prednisone - Prostatic Neoplasms | Phase 2 | Completed | Pfizer | 204 | 2006-05-01 | 2013-04-11 |
| Study Of Anti-IGF-IR CP-751,871 In Patients With Solid Tumors CP-751,871 - Sarcoma, Ewing's | Phase 1 | Completed | Pfizer | 65 | 2005-08-01 | 2013-12-17 |
| CP-751,871 In Combination With Docetaxel In Advance Non-hematologic Malignancies CP-751,871, Docetaxel - Advanced Non-Hematologic Malignancies | Phase 1 | Completed | Pfizer | 46 | 2005-03-01 | 2013-10-30 |
| Combination Study Of CP-751,871 With Paclitaxel And Carboplatin In Advanced Lung Cancer CP-751,871, paclitaxel, carboplatin - Carcinoma, Non-Small-Cell Lung | Phase 1 / Phase 2 | Completed | Pfizer | 282 | 2005-02-01 | 2013-10-30 |
| CP-751,871 Treatment For Patients With Multiple Myeloma CP-751,871 - Multiple Myeloma | Phase 1 | Completed | Pfizer | 47 | 2003-12-01 | 2013-03-15 |
| CP-751871 In Treating Women With Early-Stage Breast Cancer That Can Be Removed By Surgery figitumumab, imaging biomarker analysis, laboratory biomarker analysis - Breast Cancer | Phase 1 | Withdrawn | Pfizer | 2015-03-11 |
Carcinoma, Non-Small-Cell Lung (6) · Breast Neoplasms (4) · Carcinoma, Squamous Cell (3) · Carcinoma, Large Cell (2) · Prostatic Neoplasms (2) · Sarcoma (2) · Breast Diseases (1) · Carcinoma (1) · Carcinoma, Adenosquamous (1) · Colorectal Neoplasms (1) · Head and Neck Neoplasms (1) · Lung Neoplasms (1) · Multiple Myeloma (1) · Neoplasm Metastasis (1) · Recurrence (1)
Pfizer (18) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · Suzanne George, MD (1)
United States (13) · Canada (8) · Spain (7) · United Kingdom (6) · Italy (5) · Belgium (4) · Brazil (4) · Germany (4) · France (3) · Hungary (3) · Switzerland (3) · Australia (2) · Bulgaria (2) · Chile (2) · Czechia (2)
Douglas Yee, MD (1) · Jean-Pascal Machiels, MDPhD (1) · Suzanne George, MD (1)
PMID 20036194, PMID 21748299, PMID 22025154, PMID 22682017, PMID 24536060, PMID 24888810, PMID 25395283, PMID 38468440, PMID 41332393
P30CA077598 (1)