Farydak: Clinical Trials

6 trials of Farydak, newest first

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4 completed, 2 terminated. 6 Phase 2, 2 Phase 1.

By phase and status

PhaseTrialsStatus
Phase 26Completed 4, Terminated 2
Phase 12Completed 2

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Trials (filtered) newest first · largest first

All 6 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Panobinostat, Carfilzomib, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma
Carfilzomib, Chemosensitivity Assay, Dexamethasone - Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma
Phase 2TerminatedUniversity of Washington92018-02-082022-05-09
A Trial Evaluating Efficacy & Safety of RVD +/- Panobinostat in Transplant Eligible, Newly Diagnosed Multiple Myeloma (NDMM)
Revlimid, Velcade, dexamethasone - Multiple Myeloma
Phase 2TerminatedNovartis Pharmaceuticals62016-06-142018-07-24
Reducing the Residual Reservoir of HIV-1 Infected Cells in Patients Receiving Antiretroviral Therapy
Panobinostat, Pegylated Interferon-alpha2a - HIV Infection
Phase 1 / Phase 2CompletedMassachusetts General Hospital172016-05-012024-02-28
Panobinostat/Bortezomib/Dexamethasone in Relapsed or Relapsed-and-refractory Multiple Myeloma
Panobinostat Capsules, Bortezomib Injection, Dexamethasone tablets - Multiple Myeloma
Phase 2Completedpharmaand GmbH2482016-04-272024-07-12
Panobinostat (LBH589): Acute Graft Versus Host Disease (aGVHD) Prevention
Panobinostat, Sirolimus, Tacrolimus - Graft Versus Host Disease, GVHD
Phase 2CompletedH. Lee Moffitt Cancer Center and Research Institute422016-03-042021-07-21
LBH589 and Bevacizumab in Patients With Recurrent High Grade Glioma
LBH589, bevacizumab - Malignant Glioma
Phase 1 / Phase 2CompletedPatrick Y. Wen, MD512009-03-012017-03-14

Conditions studied

Multiple Myeloma (3)  ·  Glioma (1)  ·  Graft vs Host Disease (1)  ·  HIV Infections (1)  ·  Hematologic Diseases (1)  ·  Recurrence (1)

Sponsors

H. Lee Moffitt Cancer Center and Research Institute (1)  ·  Massachusetts General Hospital (1)  ·  Novartis Pharmaceuticals (1)  ·  Patrick Y. Wen, MD (1)  ·  University of Washington (1)  ·  pharmaand GmbH (1)

Countries

United States (6)  ·  Australia (1)  ·  Belgium (1)  ·  Brazil (1)  ·  Canada (1)  ·  Czechia (1)  ·  France (1)  ·  Germany (1)  ·  Greece (1)  ·  Hungary (1)  ·  Italy (1)  ·  Lebanon (1)  ·  Netherlands (1)  ·  Norway (1)  ·  Poland (1)

Top investigators

Andrew Cowan (1)  ·  Daniel R Kuritzkes, MD (1)  ·  Lia Perez, M.D. (1)  ·  Mathias Lichterfeld, MD, PhD (1)  ·  Patrick Y. Wen, MD (1)  ·  Rajesh T Gandhi, MD (1)

Results publications

PMID 21984064, PMID 25572329, PMID 33301738, PMID 34242388, PMID 37189240

NIH funding

2015 (1), P30CA015704 (1)