16 completed. 12 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 12 | Completed 12 |
| Phase 1 | 3 | Completed 3 |
| Phase 3 | 1 | Completed 1 |
Follow exatecan: new trials by email Literature Review of exatecan trials Research Report on exatecan
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Exatecan Mesylate in Treating Patients With Ewing's Sarcoma, Primitive Neuroectodermal Tumor, or Desmoplastic Small Round Cell Tumor exatecan mesylate - Sarcoma | Phase 2 | Completed | Daiichi Sankyo | 2003-01-01 | 2012-05-16 | |
| Exatecan Mesylate in Treating Children With Relapsed or Refractory Rhabdomyosarcoma exatecan mesylate - Sarcoma | Phase 2 | Completed | Daiichi Sankyo | 2003-01-01 | 2012-05-16 | |
| Exatecan Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma exatecan mesylate - Sarcoma | Phase 2 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 39 | 2002-05-01 | 2012-07-18 |
| Exatecan Mesylate in Treating Patients With Advanced Solid Tumors and Kidney Dysfunction exatecan mesylate - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | Jonsson Comprehensive Cancer Center | 2002-05-01 | 2013-07-10 | |
| Gemcitabine With or Without Exatecan Mesylate in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer exatecan mesylate, gemcitabine hydrochloride - Pancreatic Cancer | Phase 3 | Completed | Daiichi Sankyo | 2001-07-01 | 2012-05-16 | |
| DX-8951f in Treating Patients With Metastatic Stomach Cancer exatecan mesylate - Esophageal Cancer, Gastric Cancer | Phase 2 | Completed | Daiichi Sankyo | 2001-04-01 | 2012-05-16 | |
| DX-8951f in Treating Patients With Biliary Cancer exatecan mesylate - Extrahepatic Bile Duct Cancer, Gallbladder Cancer | Phase 2 | Completed | Daiichi Sankyo | 2000-03-01 | 2012-05-16 | |
| DX-8951f in Treating Women Who Have Advanced or Recurrent Cancer of the Cervix exatecan mesylate - Cervical Cancer | Phase 2 | Completed | Daiichi Sankyo | 2000-01-01 | 2012-05-16 | |
| DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas filgrastim, exatecan mesylate - Brain and Central Nervous System Tumors, Lymphoma | Phase 1 | Completed | Daiichi Sankyo | 1999-09-01 | 2012-05-16 | |
| DX-8951f in Treating Patients With Liver Cancer exatecan mesylate - Liver Cancer | Phase 2 | Completed | Daiichi Sankyo | 1999-09-01 | 2012-05-16 | |
| Chemotherapy in Treating Patients With Recurrent, Metastatic, or Unresectable Ovarian, Fallopian Tube, or Peritoneal Cancer exatecan mesylate - Fallopian Tube Cancer, Ovarian Cancer | Phase 2 | Completed | Daiichi Sankyo | 1999-07-01 | 2012-05-16 | |
| DX-8951f in Treating Patients With Metastatic Cancer of the Pancreas exatecan mesylate - Pancreatic Cancer | Phase 2 | Completed | Daiichi Sankyo | 37 | 1999-06-01 | 2012-05-16 |
| Chemotherapy in Treating Women With Metastatic Breast Cancer exatecan mesylate - Breast Cancer | Phase 2 | Completed | Daiichi Sankyo | 1999-06-01 | 2012-05-16 | |
| Chemotherapy in Treating Patients With Prostate Cancer exatecan mesylate - Prostate Cancer | Phase 2 | Completed | Daiichi Sankyo | 1999-06-01 | 2012-05-16 | |
| Chemotherapy in Treating Patients Who Have Hematologic Cancer exatecan mesylate - Leukemia, Myelodysplastic Syndromes | Phase 1 | Completed | Daiichi Sankyo | 1999-06-01 | 2012-05-16 | |
| DX-8951f in Treating Previously Untreated Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer exatecan mesylate - Lung Cancer | Phase 2 | Completed | Daiichi Pharmaceuticals | 1999-02-01 | 2013-07-10 |
Sarcoma (3) · Carcinoma, Hepatocellular (2) · Liver Neoplasms (2) · Pancreatic Neoplasms (2) · Adenocarcinoma Of Esophagus (1) · Anemia, Refractory, with Excess of Blasts (1) · Astrocytoma (1) · Bile Duct Neoplasms (1) · Blast Crisis (1) · Breast Neoplasms (1) · Burkitt Lymphoma (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Ovarian Epithelial (1) · Central Nervous System Neoplasms (1) · Choroid Plexus Neoplasms (1)
Daiichi Sankyo (13) · Daiichi Pharmaceuticals (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · Jonsson Comprehensive Cancer Center (1)
United States (14) · Canada (4) · Germany (2) · Belgium (1) · Denmark (1) · Finland (1) · Italy (1) · Netherlands (1) · Puerto Rico (1) · Slovakia (1) · United Kingdom (1)
Robert L. DeJager, MD, FACP (13) · Carolyn Britten, MD (1) · Nick Thatcher, PhD, FRCP (1) · Peter Reichardt, MD (1)
PMID 12114413, PMID 12871785, PMID 16133799, PMID 16983112, PMID 17336054