4 completed, 3 recruiting, 1 terminated. 4 Phase 2, 1 Early Phase 1, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Recruiting 2 |
| Early Phase 1 | 1 | Terminated 1 |
| Not applicable | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Ethionamide: new trials by email Literature Review of Ethionamide trials Research Report on Ethionamide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of the Early Effects, Safety, and Acceptability of Oral Alpibectir in Combination With Ethionamide Alpibectir 45 mg once daily (OD) plus Ethionamide 125 mg OD, Alpibectir 45 mg OD plus Ethionamide 250 mg OD, Isoniazid, rifampicin, pyrazinamide and ethambutol fixed dose combination, weight based - Tuberculosis | Phase 2 | Recruiting | TASK Applied Science | 60 | 2025-03-03 | 2025-03-07 |
| PanACEA - STEP2C -01 BTZ-043, Rifampicin, Isoniazid - Pulmonary Tuberculosis, Other Specified Pulmonary Tuberculosis | Phase 2 | Recruiting | Michael Hoelscher | 390 | 2023-04-14 | 2025-10-07 |
| A Phase 2 Trial to Evaluate the EBA, Safety and Tolerability of Eto Alone and in Combination With BVL-GSK098 BVL-GSK098 9mg, Ethionamide 250mg, Ethionamide 250 mg - Rifampicin- and Isoniazid-Susceptible Pulmonary Tuberculosis (TB) | Phase 2 | Completed | TASK Applied Science | 105 | 2022-12-06 | 2025-08-21 |
| Population Pharmacokinetics of Anti-tuberculosis Drugs in Children With Tuberculosis anti-tuberculosis drug - Tuberculosis | Recruiting | Beijing Children's Hospital | 800 | 2018-07-01 | 2018-08-15 | |
| An Open-label RCT to Evaluate a New Treatment Regimen for Patients With Multi-drug Resistant Tuberculosis Linezolid, Bedaquiline, Levofloxacin - Tuberculosis, Multidrug Resistant Tuberculosis | Phase 2 / Phase 3 | Completed | University of Cape Town | 154 | 2015-11-12 | 2021-09-29 |
| Patients Response to Early Switch To Oral:Osteomyelitis Study oral antibiotics, intravenous antibiotics - Osteomyelitis | Early Phase 1 | Terminated | Julio Ramirez | 11 | 2014-03-06 | 2021-04-06 |
| Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy atazanavir/cobicistat, darunavir/ritonavir dosage #1, darunavir/ritonavir dosage #2 - HIV Infections | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 1578 | 2003-06-09 | 2025-12-02 | |
| A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDRTB) in HIV-Infected Patients. Cycloserine, Ethionamide, Capreomycin sulfate - HIV Infections, Tuberculosis | Not applicable | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 525 | 2021-11-03 |
Tuberculosis (5) · Tuberculosis, Pulmonary (3) · HIV Infections (2) · AIDS-Related Opportunistic Infections (1) · Acquired Immunodeficiency Syndrome (1) · Extensively Drug-Resistant Tuberculosis (1) · Osteomyelitis (1) · Tuberculosis, Multidrug-Resistant (1)
National Institute of Allergy and Infectious Diseases (NIAID) (2) · TASK Applied Science (2) · Beijing Children's Hospital (1) · Julio Ramirez (1) · Michael Hoelscher (1) · University of Cape Town (1)
South Africa (5) · United States (3) · Tanzania (2) · Argentina (1) · Botswana (1) · Brazil (1) · China (1) · Gabon (1) · Malawi (1) · Mozambique (1) · Puerto Rico (1) · Thailand (1) · Uganda (1)
A-Dong Shen, Master (1) · Benson C (1) · Chirgwin K (1) · David Seligson, MD (1) · Gifty Okyere-Manu, MBChB (1) · Julio Ramirez, MD (1) · Keertan Dheda, MBChB (1) · Mark Mirochnick, MD (1) · Michael Hoelscher, Prof Dr. (1) · Reinard McPherson, MBChB (1) · Sepkowitz K (1) · Telzak E (1) · Wei Zhao, Doctor (1) · Yu-Jie Qi, Master (1)
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