3 active not recruiting, 2 completed, 1 recruiting. 3 Phase 2, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Active not recruiting 2, Completed 1 |
| Phase 1 | 2 | Active not recruiting 1, Recruiting 1 |
| Phase 3 | 2 | Active not recruiting 1, Completed 1 |
Follow Erwinia asparaginase: new trials by email Literature Review of Erwinia asparaginase trials Research Report on Erwinia asparaginase
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Venetoclax Basket Trial for High Risk Hematologic Malignancies Venetoclax, Azacitidine, Cytarabine - Myelodysplastic Syndromes, de Novo, Myelodysplastic Syndromes, Secondary | Phase 1 | Recruiting | Andrew E. Place, MD | 30 | 2023-03-29 | 2026-03-12 |
| Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and Navitoclax Venetoclax, Navitoclax, Dexamethasone - Refractory Acute Lymphoblastic Leukemia, Relapsed Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Active not recruiting | St. Jude Children's Research Hospital | 35 | 2022-08-25 | 2026-10-15 |
| A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia Azacitidine, Decitabine, Cytarabine - Acute Myeloid Leukemia, Myelodysplastic Syndromes | Phase 2 | Active not recruiting | St. Jude Children's Research Hospital | 206 | 2017-06-15 | 2026-04-23 |
| Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents Pegaspargase, Erwinia asparaginase, Cyclophosphamide - Acute Lymphoblastic Leukemia, Pediatric | Phase 3 | Active not recruiting | Dana-Farber Cancer Institute | 560 | 2017-03-03 | 2026-07-16 |
| NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic Lymphoma Prednisone, Vincristine, Daunorubicin - Lymphoblastic Lymphoma | Phase 2 | Completed | St. Jude Children's Research Hospital | 23 | 2012-05-25 | 2022-06-28 |
| A Study of Children With Refractory or Relapsed ALL Topotecan, dexamethasone, vincristine, E. coli Asparaginase, PEG-L-asparaginase, erwinia asparaginase - Acute Lymphoblastic Leukemia | Phase 3 | Completed | St. Jude Children's Research Hospital | 40 | 1997-02-01 | 2008-06-04 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (5) · Myelodysplastic Syndromes (2) · Leukemia (1) · Leukemia, Biphenotypic, Acute (1) · Leukemia, Myeloid, Acute (1) · Neoplasm Metastasis (1) · Recurrence (1)
St. Jude Children's Research Hospital (4) · Andrew E. Place, MD (1) · Dana-Farber Cancer Institute (1)
United States (6) · Canada (1)
Andrew E Place, MD, PhD (1) · Hiroto Inaba, MD,PhD (1) · Melissa Burns, MD (1) · Raul C. Ribiero, MD (1) · Seth E. Karol, MD (1) · Sima Jeha, MD (1)