8 unknown, 2 completed. 10 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Unknown 8, Completed 2 |
| Phase 2 | 1 | Unknown 1 |
Follow Endostatins: new trials by email Literature Review of Endostatins trials Research Report on Endostatins
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Endostar Plus EGFR-TKI（Epidermal Growth Factor Receptor-Tyrosine-Kinase Inhibitor） as a Treatment of EGFR Mutation-positive NSCLC EGFR-TK Inhibitor - Advanced Cancer, Lung Cancer, Nonsmall Cell | Phase 3 | Unknown | Zaiwen Fan | 80 | 2017-02-01 | 2017-01-04 |
| Endostar Combined With Concurrent Chemoradiotherapy for Locoregionally Advanced Nasopharyngeal Carcinoma Endostar, DDP - Nasopharyngeal Carcinoma | Phase 3 | Unknown | First Affiliated Hospital of Guangxi Medical University | 300 | 2016-10-01 | 2016-09-20 |
| Systemic Chemotherapy Combined With Recombinant Human Adenovirus Type 5 and Endostatin Injections for Treatment Malignant Hydrothorax in NSCLC Patients Gemcitabine, Vinorelbine, Paclitaxel - Malignant Hydrothorax, Non Small Cell Lung Cancer | Phase 3 | Unknown | Xinqiao Hospital of Chongqing | 134 | 2016-10-01 | 2016-10-21 |
| Endostar Combination With Chemotherapy and EGFR-TKI in Lung Cancer Rechallenging Treatment After Acquired Resistance. Recombinant human endostatin, Placebo - Lung Cancer | Phase 2 / Phase 3 | Unknown | Peking University Third Hospital | 60 | 2014-01-01 | 2015-01-29 |
| Endostatin in Combination With Chemotherapy for Metastatic Nasopharyngeal Carcinoma Recombinant Human Endostatin plus gemcitabine and cisplatin, Gemcitabine and cisplatin - Effects of Chemotherapy, Stage IVC Nasopharyngeal Carcinoma | Phase 3 | Unknown | Zhejiang Cancer Hospital | 362 | 2013-08-01 | 2015-01-01 |
| E10A for the Treatment of Squamous Cell Carcinoma of the Head and Neck Endostatins, Paclitaxel injection, Cisplatin injection - Head and Neck Neoplasms | Phase 3 | Unknown | Guangzhou Double Bioproducts Co., Ltd | 540 | 2013-06-01 | 2015-12-15 |
| Recombinant Endostatin Combined With Vinorelbine and Cisplatin in Patients With Advanced Non-small Cell Lung Cancer Placebos, Sulijia - Advanced Non-small Cell Lung Cancer | Phase 3 | Completed | Jiangsu Wuzhong Pharmaceutical Group Co., Ltd. | 560 | 2011-11-10 | 2017-04-17 |
| Trial of Neoadjuvant Endostar, Docetaxel and Epirubicin for Patients With Breast Cancer docetaxel and epirubicin, docetaxel and epirubicin plus endostatin - Breast Cancer | Phase 3 | Unknown | Xijing Hospital | 800 | 2011-10-01 | 2011-11-24 |
| Adjuvant Vinorelbine Plus Cisplatin(NP) Versus NP Plus Endostar in Patients With Completely Resected Stage IB-IIIA Non-small Cell Lung Cancer(NSCLC) recombinant human endostatin - Non-small Cell Lung Cancer | Phase 3 | Completed | Shanghai Jiao Tong University School of Medicine | 250 | 2007-07-01 | 2010-05-17 |
| Adjuvant Vinorelbine Plus Cisplatin (NP) Versus NP Plus Endostar in Patients With Completely Resected Stage IB-IIIA Non-small Cell Lung Cancer recombinant human endostatin - Non-small Cell Lung Cancer | Phase 3 | Unknown | Chinese Academy of Sciences | 1108 | 2007-06-01 | 2010-03-09 |
Carcinoma, Non-Small-Cell Lung (5) · Nasopharyngeal Carcinoma (2) · Breast Neoplasms (1) · Head and Neck Neoplasms (1) · Lung Neoplasms (1)
Chinese Academy of Sciences (1) · First Affiliated Hospital of Guangxi Medical University (1) · Guangzhou Double Bioproducts Co., Ltd (1) · Jiangsu Wuzhong Pharmaceutical Group Co., Ltd. (1) · Peking University Third Hospital (1) · Shanghai Jiao Tong University School of Medicine (1) · Xijing Hospital (1) · Xinqiao Hospital of Chongqing (1) · Zaiwen Fan (1) · Zhejiang Cancer Hospital (1)
China (8)
Huiqiang Huang, Ph.D (1) · Jianghao Chen, MD, PhD (1) · Jie He, M.D. & Ph.D. (1) · Li Liang, MD (1) · Liao Meilin, M.D. (1) · Ling Wang, MD (1) · Xiaozhong Chen (1) · Yuankai Shi, M.D. (1)
PMID 10640954, PMID 11212235, PMID 15746043, PMID 15752890, PMID 15920746, PMID 16139912, PMID 17426445, PMID 19564532, PMID 22537906, PMID 24662947, PMID 29238974