16 completed, 4 terminated, 3 unknown, 1 withdrawn. 10 Not applicable, 7 Phase 4, 3 Phase 2, 3 Phase 3, 1 Early Phase 1.
Follow EMLA Cream: new trials by email Literature Review of EMLA Cream trials Research Report on EMLA Cream
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effects of EMLA Cream and Cold Application on Pain, Fear and Vital Signs Before Chest Tube Removal in Children EMLA Cream, Cold application - Chest Tube Removal, Children | Not applicable | Completed | Istanbul Medeniyet University | 66 | 2025-04-05 | 2025-07-14 |
| Reducing Port Access Pain and Clinic Wait Time: An Evaluation of EMLA Cream Versus nüm™ Vapocoolant Spray Num Vapocoolant Spray, EMLA Cream - Pediatric Cancer | Phase 4 | Withdrawn | Marianne Hutti | 2023-12-23 | 2024-11-14 | |
| EMLA Cream as Analgesic for Outpatient Gynecological Procedures EMLA Cream, VersaPro Cream Base for Compounding - Pain | Phase 4 | Completed | CAMC Health System | 31 | 2023-09-15 | 2026-08-31 |
| Local Anesthesia Before Bulkamid Injection Topical lidocaine, EMLA cream, Periurethral block - Stress Urinary Incontinence, Intrinsic Sphincter Deficiency | Not applicable | Terminated | Medstar Health Research Institute | 23 | 2023-09-01 | 2025-05-16 |
| Comparison Between Lidocaine Prilocaine Cream and Lidocaine Injection on Pain Control During Episiotomy. 10 ml of lidocaine 2%, lidocaine prilocaine cream 15gm - Episiotomy Wound | Not applicable | Completed | Cairo University | 60 | 2022-09-01 | 2024-11-20 |
| Emla Cream Versus Benzocaine on Analgesia EMLA Cream, Benzocaine Gel - Effect of Drug | Early Phase 1 | Completed | Dow University of Health Sciences | 70 | 2021-11-17 | 2022-07-29 |
| Comparative Study of Two Topical Anesthetics Prior to Fractional Nonablative Laser Treatment of the Face 2.5 g of lidocaine 23% / tetracaine 7% ointment without occlusion, 7.5 g lidocaine 2.5%/ prilocaine 2.5% cream with occlusion - Anesthesia, Local, Photodamaged Skin | Phase 2 / Phase 3 | Completed | Mayo Clinic | 22 | 2021-01-08 | 2026-02-20 |
| Pharmacological and Non-pharmacological Interventions in Management of Venipuncture Pain. EMLA application, Distraction techniques, EMLA cream and distraction techniques - Child, Hospitalized | Not applicable | Completed | Children's Hospital of Fudan University | 354 | 2020-02-01 | 2023-09-21 |
| The Effect of Combined Oral and Topical Analgesics to Reduce Pain Perception During Electrodiagnostic Testing EMLA Cream, Ibuprofen, Placebo syrup - Pain Perception | Not applicable | Completed | Aga Khan University Hospital, Pakistan | 113 | 2019-12-30 | 2023-02-28 |
| Comparison of Two Analgesic Pretreatment Techniques Before Spinal Needle Insertion for Pain Reduction and Maternal Satisfaction Level Assessment in Women Undergoing LSCS. EMLA cream, 2% lidocaine - Anesthesia, Spinal, Pain | Not applicable | Completed | Aga Khan University | 62 | 2019-11-13 | 2020-04-08 |
| Concepts for Analgosedation During Placement of Regional Anaesthesia Before Operations. Fentanyl, Remifentanil, Clonidine - Knee Arthropathy, Hip Arthritis | Phase 4 | Completed | Medical University of Graz | 50 | 2019-07-26 | 2019-10-21 |
| Transcutaneous Electrical Nerve Stimulation for Local Anaesthesia TENS machine, EMLA cream - Donor Site Complication, Skin Graft | Not applicable | Terminated | University Hospitals, Leicester | 8 | 2019-07-01 | 2023-12-06 |
| Single-centre Study to Investigate Safety and Efficacy of Tri-Solfen in Wound Debridement Tri-Solfen Gel (Lidocaine HCl, Bupivacaine HCl, Adrenaline Acid Tartrate /Cetrimide), EMLA cream, Post Operative Analgesia (Paracetamol, Ibuprofen) - Wounds Injuries, Anesthesia, Local | Phase 2 | Unknown | Medical Ethics UK Ltd | 90 | 2019-01-15 | 2019-03-06 |
| Pharmacological and Nonpharmacological Methods for Children in Venipuncture Pain EMLA Cream, Buzzy, Cold spray - Procedural Pain Relief, Fear Pain | Not applicable | Completed | Aynur Aytekin Ozdemir | 192 | 2018-03-29 | 2025-03-28 |
| Spray vs EMLA Cream on Pain During Intra-articular Injection Walter Ritter Ethyl Chloride Spray, Placebo Spray, Placebo Cream - Adhesive Capsulitis of the Shoulder | Phase 4 | Unknown | Soonchunhyang University Hospital | 63 | 2018-03-14 | 2019-04-08 |
| The Effect of Lidocaine - Prilocaine Cream (EMLA) Versus Mepivacaine Infiltration on Pain Relief During And After Mediolateral Episiotomies Lidocaine-prilocaine cream, mepivacaine infiltration group, mediolateral episiotomy - Episiotomy Pain | Phase 4 | Unknown | Cairo University | 200 | 2017-08-01 | 2017-08-29 |
| Fractional Laser Assisted Topical Anesthesia AFXL, AHES, EMLA cream - Cicatrix | Phase 4 | Terminated | Netherlands Institute for Pigment Disorders | 3 | 2015-06-01 | 2019-03-13 |
| Fractional Laser Assisted Delivery of Anesthetics AFXL, AHES, EMLA cream - Local Anesthesia of the Skin. | Phase 4 | Completed | Netherlands Institute for Pigment Disorders | 10 | 2014-09-01 | 2014-11-10 |
| Analgesic Effect of Trigger Point Injection and EMLA for Shoulder Pain in Laparoscopic Hysterectomy TPI, EMLA cream - Myoma of Uterus | Not applicable | Completed | Yonsei University | 75 | 2013-04-01 | 2014-02-05 |
| Jet Injection of 1% Buffered Lidocaine Versus Topical EMLA for Local Anesthesia Before Lumbar Puncture in Children J-Tip, EMLA, Lidocaine - Lumbar Puncture, Topical Analgesia | Not applicable | Terminated | University of Colorado, Denver | 66 | 2012-09-01 | 2019-06-21 |
Showing 20 of 24. Sign in to see all of them.
Pain (3) · Agnosia (1) · Bursitis (1) · Cicatrix (1) · Diabetes Mellitus (1) · Dyspareunia (1) · Fractures, Closed (1) · Neoplasms (1) · Pain, Procedural (1) · Urinary Incontinence, Stress (1) · Wounds and Injuries (1)
Cairo University (2) · Netherlands Institute for Pigment Disorders (2) · Aga Khan University (1) · Aga Khan University Hospital, Pakistan (1) · Aynur Aytekin Ozdemir (1) · CAMC Health System (1) · Children's Hospital of Fudan University (1) · Dow University of Health Sciences (1) · Genzyme, a Sanofi Company (1) · Istanbul Medeniyet University (1) · Lund University Hospital (1) · Marianne Hutti (1) · Mayo Clinic (1) · Medical Ethics UK Ltd (1) · Medical University of Graz (1)
United States (8) · Pakistan (3) · Egypt (2) · Netherlands (2) · South Korea (2) · Turkey (Türkiye) (2) · United Kingdom (2) · Austria (1) · China (1) · Sweden (1)
Albert Wolkerstorfer, MD, PhD (2) · Menno A. De Rie, MD, PhD (2) · Ahmed Maged, MD (1) · Ahmed S Alharty, MD (1) · Alex Poulsen, DO (1) · Aynur Aytekin Ozdemir (1) · Aynur Aytekin Ozdemir, Professor (1) · Catherine C Skae, MD (1) · Elika Hoss (1) · Fazal Rehman, MBBS, FCPS (1) · Gregor A Schittek, MD (1) · Haris Hakeem, MBBS, FCPS, FRACP (1) · Kathleen Adelgais, MD, MPH (1) · Keith Harding (1)
PMID 10781447, PMID 20636964, PMID 28285862, PMID 29160002, PMID 32445850, PMID 33485746, PMID 34387216, PMID 36737707, PMID 38142386
2008 (1), 2018 (1)