18 completed. 18 Phase 2, 6 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 18 | Completed 18 |
| Phase 1 | 6 | Completed 6 |
| Phase 3 | 1 | Completed 1 |
Follow Electrocardiogram: new trials by email Literature Review of Electrocardiogram trials Research Report on Electrocardiogram
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction Low calorie meal replacement plan, Cardiovascular magnetic resonance (CMR) imaging and magnetic resonance spectroscopy, Transthoracic echocardiography - Heart Failure With Preserved Ejection Fraction, Heart Failure, Diastolic | Phase 2 / Phase 3 | Completed | University of Leicester | 66 | 2023-12-05 | 2026-07-22 |
| Evaluation of GeranylGeranylAcetone in Heart Failure With Preserved Ejection Fraction Iohexol measurement, Geranylgeranylacetone (GGA), Echocardiography - Heart Failure With Preserved Ejection Fraction | Phase 2 | Completed | Amsterdam UMC, location VUmc | 43 | 2023-04-26 | 2025-04-01 |
| Study of VIP152, Venetoclax, and Prednisone (VVIP) in Relapsed/Refractory Lymphoid Malignancies Vysis LSI MYC Break Apart Rearrangement Probe Kit, Venetoclax, VIP152 - Lymphoma, Non-Hodgkin Lymphoma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 8 | 2023-04-05 | 2026-02-23 |
| Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis Paclitaxel, Nilotinib, ECG - Gynecologic Cancer, Gynecologic Neoplasms | Phase 2 | Completed | National Cancer Institute (NCI) | 21 | 2022-10-13 | 2026-06-25 |
| Phase 2 Study of Bintrafusp Alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON). Bintrafusp alfa/M7824, Ibuprofen, PET scan - Olfactory Neuroblastoma, Esthesioneuroblastoma | Phase 2 | Completed | National Cancer Institute (NCI) | 11 | 2022-06-21 | 2025-08-08 |
| Superenhancer Inhibitor Minnelide in Advanced Refractory Adenosquamous Carcinoma of the Pancreas (ASCP) Minnelide, ECG, CT/MRI - Adenosquamous Carcinoma of the Pancreas | Phase 2 | Completed | National Cancer Institute (NCI) | 16 | 2022-03-07 | 2026-08-14 |
| Front Line Ibrutinib Without Corticosteroids for Newly Diagnosed Chronic Graft-versus-Host Disease Ibrutinib, ECG, PFT's - Chronic GVHD | Phase 2 | Completed | National Cancer Institute (NCI) | 10 | 2021-05-10 | 2026-01-23 |
| A Trial of the Safety and Immunogenicity of the COVID-19 Vaccine (mRNA-1273) in Participants With Hematologic Malignancies and Various Regimens of Immunosuppression, and in Participants With Solid Tumors on PD1/PDL1 Inhibitor Therapy Messenger ribonucleic acid (mRNA)-1273 Vaccine, Messenger ribonucleic acid (mRNA)-1273 Vaccine Booster, ECG - Solid Tumor Malignancy, Hematologic Malignancy | Phase 2 | Completed | National Cancer Institute (NCI) | 19 | 2021-04-28 | 2024-08-27 |
| HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers PRGN-2009, M7824, EKG - HPV Positive Cancer, Vulvar, Vaginal, Penile, Rectal Cancer | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 39 | 2020-08-11 | 2026-08-18 |
| Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the Liver Codman 3000 constant flow pump catheter, Panitumumab, FUDR-Dex - Colorectal Cancer, Liver Metastases | Phase 2 | Completed | National Cancer Institute (NCI) | 24 | 2019-06-24 | 2026-08-28 |
| Improving Right Ventricular Function in Young Adults Born Preterm Pulmonary Function Testing, Electrocardiogram, Cardiac Magnetic Resonance Imaging - Infant,Premature | Phase 2 | Completed | University of Wisconsin, Madison | 10 | 2018-10-30 | 2021-03-17 |
| M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers M7824, Topotecan, Temozolomide - Carcinoma, Small Cell, Lung Cancer | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 37 | 2018-09-11 | 2025-05-09 |
| Phase I/II Study of Immunotherapy Combination BN-Brachyury Vaccine, M7824, N-803 and Epacadostat (QuEST1) M7824, N-803, MVA-BN-Brachyury - Metastatic Castration-resistant Prostate Cancer, Prostate Cancer | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 59 | 2018-05-01 | 2025-09-30 |
| Pilot Study of Aprepitant Effect on Aldosterone Secretion in Diabetic Patient (Diabetes Mellitus) With Hypertension Associated With Low Renin Blood sampling, Blood Pressure Measurement, electrocardiogram - Type 2 Diabetes, Hypertension | Phase 2 | Completed | University Hospital, Rouen | 5 | 2017-07-13 | 2026-03-24 |
| Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology Surgery, Cisplatin, Mitomycin C - Gastric Adenocarcinoma, Esophagogastric Junction | Phase 2 | Completed | National Cancer Institute (NCI) | 27 | 2017-06-05 | 2025-02-19 |
| E7 TCR T Cells for Human Papillomavirus-Associated Cancers E7 TCR cells, Aldesleukin, Fludarabine - Papillomavirus Infections, Cervical Intraepithelial Neoplasia | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 224 | 2017-01-27 | 2026-03-09 |
| Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation Rituximab, Conditioning chemotherapy, TMS - Myelodysplastic Syndromes, Hodgkin's Lymphoma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 34 | 2015-09-24 | 2025-09-30 |
| Effect of Tenofovir DF on Bone Metabolism in Children Eye exam, Oral exam, CT scan - HIV Infections | Phase 2 | Completed | National Cancer Institute (NCI) | 50 | 2004-06-01 | 2008-03-04 |
Hematologic Neoplasms (3) · Lymphoma (3) · Colorectal Neoplasms (2) · Diabetes Mellitus, Type 2 (2) · Leukemia (2) · Lymphoma, Non-Hodgkin (2) · Multiple Myeloma (2) · Adenocarcinoma (1) · Anus Neoplasms (1) · Appendiceal Neoplasms (1) · Bone Diseases, Metabolic (1) · Breast Neoplasms (1) · Bronchiolitis Obliterans Syndrome (1) · Carcinoma in Situ (1) · Carcinoma, Small Cell (1)
National Cancer Institute (NCI) (14) · Amsterdam UMC, location VUmc (1) · University Hospital, Rouen (1) · University of Leicester (1) · University of Wisconsin, Madison (1)
United States (15) · France (1) · Netherlands (1) · United Kingdom (1)
Charalampos Floudas, M.D. (2) · Adriaan Voors, MD, PhD (1) · Alain Mina, M.D. (1) · Andrew M Blakely, M.D. (1) · Anish Thomas, M.D. (1) · Chen Zhao, M.D. (1) · Christopher J Melani, M.D. (1) · Gerry P McCann, MD (1) · James Gulley, M.D. (1) · James L Gulley, M.D. (1) · Jeremy L Davis, M.D. (1) · Jonathan M Hernandez, M.D. (1) · Kara N Goss, MD (1) · Loek van Heerebeek, MD, PhD (1)
PMID 30227893, PMID 33558725, PMID 33602696, PMID 35535581, PMID 37882668, PMID 39500789, PMID 39880434, PMID 40116923, PMID 40331908, PMID 42307670, PMID 42498485, PMID 42820295
1UL1TR002373-01 (1), 2015 (1)