3 recruiting, 2 completed. 2 Phase 2, 2 Phase 3, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
| Not applicable | 1 | Recruiting 1 |
Follow Dose-escalated Radiation Therapy: new trials by email Literature Review of Dose-escalated Radiation Therapy trials Research Report on Dose-escalated Radiation Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Biologically-Adapted, Dose-Escalated Radiotherapy for the Treatment of Ewing Sarcoma, BEAR Trial Biospecimen Collection, Chemotherapy, Computed Tomography - Ewing Sarcoma, Round Cell Sarcoma With EWSR1-non-ETS Fusion | Not applicable | Recruiting | Mayo Clinic | 170 | 2025-12-05 | 2026-10-06 |
| Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer Biopsy Procedure, Biospecimen Collection, Capecitabine - Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma, Stage II Pancreatic Cancer AJCC v8 | Phase 3 | Recruiting | NRG Oncology | 356 | 2025-08-21 | 2026-08-25 |
| Enhanced Local Intensified Radiation Therapy in Elderly Glioblastoma: A Phase 2 Hybrid Randomized Trial Dose-escalated radiation therapy, Standard hypofractionated radiation - Glioblastoma (GBM) | Phase 2 | Recruiting | Brigham and Women's Hospital | 56 | 2025-04-14 | 2025-09-18 |
| Spectroscopic MRI-Guided Radiation Therapy Planning in Glioblastoma Dose-Escalated Radiation Therapy, Spectroscopic Magnetic Resonance Imaging, Temozolomide - Glioblastoma, Gliosarcoma | Phase 2 | Completed | Emory University | 30 | 2017-09-20 | 2025-08-03 |
| Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer bicalutamide, flutamide, LHRH agonist (antagonist) therapy - Prostate Cancer | Phase 3 | Completed | Radiation Therapy Oncology Group | 1538 | 2009-09-01 | 2026-03-06 |
Glioblastoma (2) · Gliosarcoma (1) · Pancreatic Neoplasms (1) · Prostatic Neoplasms (1) · Sarcoma, Ewing (1)
Brigham and Women's Hospital (1) · Emory University (1) · Mayo Clinic (1) · NRG Oncology (1) · Radiation Therapy Oncology Group (1)
United States (5) · Canada (2)
Alvaro A. Martinez, MD, FACR (1) · Hui-Kuo Shu, MD, PhD (1) · Nina N Sanford (1) · Roman O. Kowalchuk, MD (1)
PMID 30854456, PMID 32548285, PMID 37104748, PMID 37218946
P30CA138292 (1), R01CA214557 (1), U10CA180868 (1)