Dfmo: Clinical Trials

3 trials of Dfmo, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

1 completed, 1 unknown, 1 withdrawn. 3 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 33Completed 1, Unknown 1, Withdrawn 1

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Trials (filtered) newest first · largest first

All 3 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients
Eflornithine, Lomustine - Anaplastic Astrocytoma, Recurrent Anaplastic Astrocytoma
Phase 3UnknownOrbus Therapeutics, Inc.3432016-07-012022-01-21
A Trial of Low Dose Sulindac Combined With Eflornithine in Patients With Familial Adenomatous Polyposis (FAP)
Eflornithine plus Sulindac, Eflornithine plus Placebo, Sulindac plus Placebo - Familial Adenomatous Polyposis
Phase 3WithdrawnCancer Prevention Pharmaceuticals, Inc.2011-03-012015-04-24
Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon Polyps
placebo, eflornithine, sulindac - Precancerous Condition
Phase 3CompletedNational Cancer Institute (NCI)3751998-07-012015-01-22

Conditions studied

Adenomatous Polyposis Coli (1)  ·  Astrocytoma (1)  ·  Brain Neoplasms (1)  ·  Colonic Polyps (1)  ·  Glioma (1)  ·  Precancerous Conditions (1)

Sponsors

Cancer Prevention Pharmaceuticals, Inc. (1)  ·  National Cancer Institute (NCI) (1)  ·  Orbus Therapeutics, Inc. (1)

Countries

United States (2)  ·  Belgium (1)  ·  Canada (1)  ·  France (1)  ·  Germany (1)  ·  Italy (1)  ·  Netherlands (1)  ·  United Kingdom (1)

Top investigators

Alfred M. Cohen, M.D. (1)  ·  Frank Meyskens (1)

Results publications

PMID 20538001, PMID 41325560

NIH funding

R01CA088078 (1)