6 completed, 2 terminated. 8 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 8 | Completed 6, Terminated 2 |
| Phase 2 | 1 | Terminated 1 |
Follow cytisine: new trials by email Literature Review of cytisine trials Research Report on cytisine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Evaluate Effect of Food on Bioavailability of Single 3 mg Tablet and Pharmacokinetics (PK) of Multiple 3 mg Doses in Healthy Adult Smokers Cytisinicline - Smoking Cessation | Phase 1 | Completed | Achieve Life Sciences | 30 | 2023-08-08 | 2023-10-18 |
| Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics of a Single 3 mg Cytisinicline Dose cytisinicline - Renal Impairment | Phase 1 | Completed | Achieve Life Sciences | 44 | 2023-01-10 | 2025-07-11 |
| Study to Evaluate Electrocardiographic Effects of Therapeutic & Supratherapeutic Doses of Cytisinicline in Healthy Smokers Cytisinicline, Placebo, Moxifloxacin - Smoking Cessation | Phase 1 | Completed | Achieve Life Sciences | 27 | 2022-10-17 | 2023-05-18 |
| A Single Dose-escalation Study of Cytisine in Adult Smokers cytisine, placebo - Smoking Cessation | Phase 1 | Completed | Achieve Life Sciences | 74 | 2019-02-28 | 2020-09-17 |
| A Study in Healthy Smokers to Investigate the Effect of Food on the Bioavailability of Cytisine in a New Formulation cytisine - Smoking Cessation | Phase 1 | Completed | Achieve Life Sciences | 13 | 2018-04-27 | 2019-09-24 |
| A Pharmacokinetic and Pharmacodynamic Evaluation of Cytisine in Healthy Smokers Cytisine - Smoking Cessation | Phase 1 / Phase 2 | Terminated | Achieve Life Sciences | 26 | 2017-10-06 | 2019-10-21 |
| A Study in Healthy Volunteers to Investigate the Effect of Food on the Bioavailability of Cytisine Cytisine - Smoking Cessation | Phase 1 | Completed | Achieve Life Sciences | 24 | 2017-08-08 | 2019-02-26 |
| Cytisine Pharmacokinetics and Dose Response (C-DRAKS 3 and C-DRAKS 4) Cytisine - Smoking Cessation | Phase 1 | Terminated | University of Auckland, New Zealand | 35 | 2016-02-01 | 2019-03-22 |
Smoking Cessation (7) · Renal Insufficiency (1) · Smoking (1)
Achieve Life Sciences (7) · University of Auckland, New Zealand (1)
Portugal (4) · United Kingdom (3) · New Zealand (1) · Spain (1)
Marlene Fonseca, MD (3) · Annelize Koch, MD (2) · Ezanul Abd Wahab, MD (1) · Soo Hee Jeong, Phd (1)
2017 (1), 2018 (1)