2 completed, 2 withdrawn, 1 terminated. 5 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 2, Withdrawn 2, Terminated 1 |
| Phase 2 | 4 | Withdrawn 2, Completed 1, Terminated 1 |
Follow CPI 613: new trials by email Literature Review of CPI 613 trials Research Report on CPI 613
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Gemcitabine and Cisplatin With or Without CPI-613 as First Line Therapy for Patients With Advanced Unresectable Biliary Tract Cancer (BilT-04) CPI 613, Gemcitabine, Cisplatin - Biliary Tract Cancer | Phase 1 / Phase 2 | Terminated | University of Michigan Rogel Cancer Center | 75 | 2020-06-23 | 2025-12-31 |
| CPI-613 in Combination With Modified FOLFIRINOX in Locally Advanced Pancreatic Cancer CPI 613, Oxaliplatin, Irinotecan - Pancreatic Cancer | Phase 1 / Phase 2 | Completed | David Bajor, MD | 49 | 2018-12-07 | 2025-01-23 |
| CPI-613 and Docetaxel in Treating Patients With Stage IIIB or IV Non-small Cell Lung Cancer 6,8-Bis(benzylthio)octanoic Acid, Docetaxel, Pharmacological Study - Stage IIIB Non-Small Cell Lung Cancer AJCC v7, Stage IV Non-Small Cell Lung Cancer AJCC v7 | Phase 1 / Phase 2 | Withdrawn | Wake Forest University Health Sciences | 2018-06-01 | 2018-08-01 | |
| 6,8-Bis(Benzylthio)Octanoic Acid, Cytarabine, and Daunorubicin Hydrochloride in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia 6,8-Bis(benzylthio)octanoic Acid, Cytarabine, Daunorubicin Hydrochloride - Untreated Adult Acute Myeloid Leukemia | Phase 1 / Phase 2 | Withdrawn | Wake Forest University Health Sciences | 2015-12-01 | 2018-07-03 | |
| CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Granulocytic Sarcoma 6,8-Bis(benzylthio)octanoic Acid, Cytarabine, Hematopoietic Cell Transplantation - Granulocytic Sarcoma, Recurrent Adult Acute Myeloid Leukemia | Phase 1 | Completed | Wake Forest University Health Sciences | 48 | 2015-09-01 | 2024-09-19 |
Biliary Tract Neoplasms (1) · Carcinoma, Non-Small-Cell Lung (1) · Cholangiocarcinoma (1) · Gallbladder Neoplasms (1) · Leukemia, Myeloid, Acute (1) · Pancreatic Neoplasms (1) · Sarcoma, Myeloid (1)
Wake Forest University Health Sciences (3) · David Bajor, MD (1) · University of Michigan Rogel Cancer Center (1)
United States (5)
Bayard Powell (1) · David Bajor, MD (1) · Stefan Grant (1) · Timothy Pardee (1) · Vaibhav Sahai, MBBS, MS (1)
P30CA012197 (3)