9 completed, 9 recruiting, 1 active not recruiting, 1 unknown. 21 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 21 | Completed 9, Recruiting 9, Active not recruiting 1, Unknown 1, Withdrawn 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mechanisms Underlying the Placebo Effect in Both Histaminergic and Non-histaminergic Itch Histamine, Cowhage - ITCH | Not applicable | Recruiting | Aalborg University | 30 | 2025-11-03 | 2025-12-04 |
| Topographical Distribution of Itch and Pain Receptors Histamine, Cowhage, Capsaicin 8% Patch - Pain, Itch | Not applicable | Recruiting | Aalborg University | 30 | 2025-09-17 | 2025-10-01 |
| Role of Interleukin-13 Pathways on Pain and Itch Sensitivity ( IL-13 ) histamine dihydrochloride, Cowhage - Itching | Not applicable | Active not recruiting | Aalborg University | 26 | 2025-05-15 | 2025-06-12 |
| Role of Interleukin-13 Pathways on Pain and Itch Sensitivity Histamine, Cowhage, bovine adrenal medulla (BAM8-22) - Itch | Not applicable | Recruiting | Aalborg University | 20 | 2025-01-06 | 2025-06-04 |
| Itch Sensation Induced by Multiple Applications of Pruritogens (temporal Summation) Histamine, Cowhage - Histamine, Cowhage | Not applicable | Recruiting | Aalborg University | 26 | 2024-11-01 | 2024-11-22 |
| The Effects of Performing a Motor Imagery Task on Cortical Excitability During Acute Experimental Muscle Pain and Acute Itch Hypertonic Saline, Histamine, Cowhage - Itch, Pain | Not applicable | Recruiting | Aalborg University | 30 | 2024-10-01 | 2024-11-22 |
| Effect of Ketamine, Amitriptyline and Their Combination on Itch Ketamine 0.5%, Amitriptyline, ketamine + amitriptyline - Itch | Not applicable | Completed | Aalborg University | 30 | 2024-08-20 | 2025-01-30 |
| Investigation of Corticospinal Excitability Aspects of Itch and Pain Hypertonic Saline, Histamine, Cowhage - Itch, Pain | Not applicable | Completed | Aalborg University | 30 | 2024-07-01 | 2024-11-22 |
| Investigate the Relationship Between Catastrophizing and the Perception of Itch Intensity in Healthy Individuals Histamine, Cowhage - Histamine, Cowhage | Not applicable | Recruiting | Aalborg University | 46 | 2024-04-27 | 2024-06-24 |
| Itch Sensation Induced by Simultaneous Application of Pruritogens (Spatial Summation) Cowhage, Histamine - Histamine, Cowhage | Not applicable | Recruiting | Aalborg University | 24 | 2024-04-01 | 2024-05-06 |
| Repetitive Applications of Pruritogens and Effects of a Cutaneous-induced Pain Stimulation on Nonhistaminergic Itch Perception Cowhage - Pain, Burning, Capsaicin | Not applicable | Unknown | Aalborg University | 30 | 2023-12-15 | 2023-12-29 |
| Repetitive Applications of Pruritogens and Effects of a Cutaneous-induced Pain Stimulation on Nonhistaminergic Itch Perception Histamine, Cowhage - Histamine, Cowhage | Not applicable | Completed | Aalborg University | 30 | 2023-12-15 | 2025-06-04 |
| Investigation of the Effects of Sleep Fragmentation on Itch and Pain Sensitivity Histamine, Cowhage - Histamine, Cowhage | Not applicable | Recruiting | Aalborg University | 30 | 2023-12-15 | 2024-11-22 |
| Investigation of the Effects of Sleep Deprivation on Itch and Pain Sensitivity Histamine, Cowhage - Histamine, Cowhage | Not applicable | Recruiting | Aalborg University | 30 | 2023-11-01 | 2023-12-20 |
| Characterization of New Human Models of Non-histaminergic Itch and Their Interaction With the TRPM8 Receptor Doxepin Topical, Papain, Histamine - Itch | Not applicable | Completed | Aalborg University | 20 | 2022-03-01 | 2022-07-20 |
| Inhibition of Non-histaminergic Pruritus Applied Using 3 Different Pruritogens Emla 1 hour, EMLA 3 hours, Vehicle cream for 1 hour - Itch | Not applicable | Completed | Aalborg University | 22 | 2021-11-15 | 2023-01-18 |
| Investigation of a New Human Model for Itch Papain, Histamine, Cowhage - Itch | Not applicable | Completed | Aalborg University | 20 | 2021-02-01 | 2021-07-09 |
| The Effect of Halophyte-based Cream on Pain and Itch Halophites-based cream 24 hours, Halophites-based cream 48 hours, Vehicle cream 24 hours - Pain, Acute, Itch | Not applicable | Completed | Aalborg University | 32 | 2020-11-12 | 2022-01-19 |
| Characterization of New Human Models of Non-histaminergic Itch Papain 10 µg, Papain 50 µg, Papain 100 µg - Papain, Itch | Not applicable | Completed | Aalborg University | 20 | 2020-09-01 | 2021-07-09 |
| Characterization of the Toll-like Receptor 7-agonist Imiquimod 3.75% As a New Surrogate Model of Itch Zyclara 3.75 % Topical Cream, Prudoxin, Histamine - Itch | Not applicable | Withdrawn | Aalborg University | 2019-11-01 | 2024-11-22 |
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Pruritus (13) · Pain (4) · Sleep Deprivation (2) · Acute Pain (1)
Aalborg University (21)
Denmark (21)
Silvia Lo Vecchio (2) · Daniele Riccio, MSc (1)