7 completed. 3 Phase 1, 3 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 3 | Completed 3 |
| Phase 3 | 2 | Completed 2 |
Follow Chronocort: new trials by email Literature Review of Chronocort trials Research Report on Chronocort
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia Chronocort, Cortef, Placebo - Congenital Adrenal Hyperplasia | Phase 3 | Completed | Neurocrine UK Limited | 55 | 2022-05-24 | 2026-10-02 |
| Long-term Safety Study of Chronocort in the Treatment of Participants With Congenital Adrenal Hyperplasia Chronocort - Congenital Adrenal Hyperplasia | Phase 3 | Completed | Immedica Pharma AB | 76 | 2022-04-01 | 2026-06-18 |
| Chronocort Versus Plenadren Replacement Therapy in Adults With Adrenal Insufficiency Chronocort, Plenadren - Primary Adrenal Insufficiency | Phase 2 | Completed | Neurocrine UK Limited | 58 | 2021-11-23 | 2026-09-14 |
| Pilot Study to Characterize and Examine the Pharmacokinetics and Efficacy of Chronocort® in Adults With CAH Hydrocortisone Modified Release Capsules - Endocrine Disease, Adrenal Insufficiency | Phase 2 | Completed | Neurocrine UK Limited | 16 | 2012-12-01 | 2026-10-02 |
| A Two-part, Study to Compare the Pharmacokinetics and Dose Proportionality of up to 6 Chronocort Formulations Chronocort - Adrenal Insufficiency, Congenital Adrenal Hyperplasia | Phase 1 | Completed | Neurocrine UK Limited | 28 | 2011-02-01 | 2026-09-14 |
| An Open Label Study in Healthy Volunteers to Compare Chronocort® to Hydrocortisone Hydrocortisone, Chronocort - Congenital Adrenal Hyperplasia, Adrenal Insufficiency | Phase 1 | Completed | Neurocrine UK Limited | 30 | 2010-03-01 | 2026-09-14 |
| Comparison of Two Forms of Hydrocortisone in Patients With Congenital Adrenal Hyperplasia Chronocort, Cortef - Congenital Adrenal Hyperplasia, 21-Hydroxylase Deficiency | Phase 1 / Phase 2 | Completed | Neurocrine UK Limited | 20 | 2007-08-01 | 2022-04-26 |
Adrenal Hyperplasia, Congenital (6) · Adrenal Insufficiency (3) · Addison Disease (1) · Adrenogenital Syndrome (1) · Congenital adrenal hyperplasia due to 21 hydroxylase deficiency (1) · Endocrine System Diseases (1)
Neurocrine UK Limited (6) · Immedica Pharma AB (1)
United States (4) · France (2) · Japan (2) · Germany (1) · United Kingdom (1)
D Merke (1) · Deborah P Merke, BS, MS, MD (1) · Girish Sharma (1) · Salvatore Febbraro (1)