6 completed, 2 active not recruiting, 2 unknown. 10 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Completed 6, Active not recruiting 2, Unknown 2 |
| Phase 2 | 4 | Completed 3, Active not recruiting 1 |
Follow cediranib: new trials by email Literature Review of cediranib trials Research Report on cediranib
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study Evaluating the Efficacy of Maintenance Olaparib and Cediranib or Olaparib Alone in Ovarian Cancer Patients Olaparib, Cediranib - Ovarian Cancer | Phase 3 | Unknown | University College, London | 330 | 2018-06-15 | 2022-09-27 |
| Testing the Combination of Cediranib and Olaparib in Comparison to Each Drug Alone or Other Chemotherapy in Recurrent Platinum-Resistant Ovarian Cancer Cediranib, Cediranib Maleate, Computed Tomography - Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma | Phase 2 / Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 582 | 2016-05-03 | 2026-10-01 |
| Testing the Use of A Single Drug (Olaparib) or the Combination of Two Drugs (Cediranib and Olaparib) Compared to the Usual Chemotherapy for Women With Platinum Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Biospecimen Collection, Carboplatin, Cediranib Maleate - Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Transitional Cell Carcinoma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 579 | 2016-03-28 | 2026-10-01 |
| Cediranib Versus Placebo Plus Cisplatin/Gemcitabine Chemotherapy for Patients With Advanced Biliary Tract Cancers gemcitabine, cisplatin, Placebo - Biliary Tract Neoplasms | Phase 2 / Phase 3 | Completed | University College, London | 124 | 2011-04-01 | 2014-10-27 |
| Cediranib, Paclitaxel, and Carboplatin in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer carboplatin, cediranib maleate, paclitaxel - Lung Cancer | Phase 3 | Completed | NCIC Clinical Trials Group | 306 | 2009-02-04 | 2023-08-22 |
| Cediranib in Combination With Lomustine Chemotherapy in Recurrent Glioblastoma Cediranib, Lomustine Chemotherapy, Placebo Cediranib - Recurrent Glioblastoma | Phase 3 | Completed | AstraZeneca | 423 | 2008-10-01 | 2016-12-28 |
| An RCT of Concurrent and Maintenance Cediranib in Women With Platinum-sensitive Relapsed Ovarian Cancer cediranib - Ovarian Cancer | Phase 3 | Unknown | Medical Research Council | 486 | 2007-07-01 | 2015-09-23 |
| Cediranib (AZD2171, RECENTIN™) in Addition to Chemotherapy in Patients With Untreated Metastatic Colorectal Cancer Cediranib, FOLFOX (5-fluorouracil, Leucovorin, Oxaliplatin), XELOX (Capecitabine and Oxaliplatin) - Metastatic Colorectal Cancer | Phase 3 | Completed | AstraZeneca | 1254 | 2006-11-01 | 2016-12-28 |
| First Line Metastatic Colorectal Cancer Therapy in Combination With FOLFOX Cediranib, Bevacizumab, 5-fluorouracil ( in FOLFOX) - Colorectal Cancer | Phase 2 / Phase 3 | Completed | AstraZeneca | 1814 | 2006-08-30 | 2017-04-14 |
| Paclitaxel + Carboplatin With/Out Cediranib Maleate in Stage III or Stage IV Non-Small Cell Lung Cancer carboplatin, cediranib maleate, paclitaxel - Lung Cancer | Phase 2 / Phase 3 | Completed | NCIC Clinical Trials Group | 296 | 2005-11-03 | 2023-08-04 |
Ovarian Neoplasms (4) · Fallopian Tube Neoplasms (3) · Carcinoma, Non-Small-Cell Lung (2) · Colorectal Neoplasms (2) · Lung Neoplasms (2) · Biliary Tract Neoplasms (1) · Glioblastoma (1) · Neoplasms (1)
AstraZeneca (3) · NCIC Clinical Trials Group (2) · National Cancer Institute (NCI) (2) · University College, London (2) · Medical Research Council (1)
Canada (7) · United Kingdom (6) · Australia (5) · United States (4) · Brazil (3) · Czechia (3) · Germany (3) · South Korea (3) · Argentina (2) · Austria (2) · Belgium (2) · France (2) · Hungary (2) · India (2) · Japan (2)
Jane Robertson (3) · Scott A. Laurie, MD, FRCPC (2) · Glenwood D. Goss, MD, BCh, FCP, FRCPC (1) · Jonathan Ledermann, Prof. (1) · Joyce F Liu (1) · Juan Valle, MD (1) · Jung-min Lee (1) · Tracy Batchelor, MD, MPH (1)
PMID 37185961, PMID 18398152, PMID 19203899, PMID 19917841, PMID 23510802, PMID 23940216, PMID 24360368, PMID 26179201, PMID 27025186, PMID 30679026, PMID 31378656, PMID 33097567, PMID 33610123, PMID 35170751, PMID 35290101, PMID 39361946, PMID 41887529
U10CA180868 (2)