2 recruiting, 2 terminated, 1 completed. 5 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Recruiting 2, Terminated 2, Completed 1 |
| Phase 2 | 2 | Recruiting 2 |
Follow capmatinib: new trials by email Literature Review of capmatinib trials Research Report on capmatinib
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations Capmatinib - Solid Tumour, Haematological Malignancy | Phase 2 / Phase 3 | Recruiting | Cancer Research UK | 30 | 2024-11-19 | 2025-11-24 |
| DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol Alectinib, Atezolizumab, Entrectinib - Haematological Malignancy, Solid Tumour | Phase 2 / Phase 3 | Recruiting | Cancer Research UK | 825 | 2023-03-01 | 2026-07-01 |
| Study Evaluating Efficacy and Safety of Capmatinib in Combination With Osimertinib in Adult Subjects With Non-small Cell Lung Cancers as Second Line Therapy Capmatinib, Osimertinib, Pemetrexed - Carcinoma, Non-Small-Cell Lung | Phase 3 | Terminated | Novartis Pharmaceuticals | 6 | 2021-09-22 | 2024-03-05 |
| Study of Capmatinib Efficacy in Comparison With Docetaxel in Previously Treated Participants With Non-small Cell Lung Cancer Harboring MET Exon 14 Skipping Mutation Capmatinib, Docetaxel - Carcinoma, Non-Small-Cell Lung | Phase 3 | Terminated | Novartis Pharmaceuticals | 22 | 2020-09-25 | 2025-05-16 |
| Molecular Profiling of Advanced Soft-tissue Sarcomas Nilotinib, Ceritinib, Capmatinib - Soft Tissue Sarcoma | Phase 3 | Completed | Institut National de la Santé Et de la Recherche Médicale, France | 603 | 2019-10-19 | 2026-04-29 |
Carcinoma, Non-Small-Cell Lung (2) · Hematologic Neoplasms (2) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Neoplasms by Site (2) · Sarcoma (2) · Carcinoma (1) · Glioma (1) · Lymphoproliferative Disorders (1) · Neoplasm Metastasis (1) · Neuroblastoma (1) · Stomach Neoplasms (1)
Cancer Research UK (2) · Novartis Pharmaceuticals (2) · Institut National de la Santé Et de la Recherche Médicale, France (1)
France (2) · South Korea (2) · United Kingdom (2) · Belgium (1) · Brazil (1) · Bulgaria (1) · Germany (1) · Hungary (1) · India (1) · Italy (1) · Japan (1) · Lithuania (1) · Malaysia (1) · Netherlands (1) · Portugal (1)
Matthew Krebs, Dr (2) · Antoine Italiano (1)
2017 (1)