4 completed, 1 terminated. 5 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 4, Terminated 1 |
Follow brivanib: new trials by email Literature Review of brivanib trials Research Report on brivanib
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Brivanib and Best Supportive Care (BSC) With Placebo and BSC for Treatment of Liver Cancer in Asian Patients Who Have Failed Sorafenib Treatment Brivanib, Placebo - Carcinoma, Hepatocellular | Phase 3 | Terminated | Bristol-Myers Squibb | 87 | 2010-05-01 | 2015-10-12 |
| Phase III Trans-Arterial Chemo-Embolization (TACE) Adjuvant HCC Brivanib, Brivanib Placebo, TACE Therapy - Hepatocellular Carcinoma | Phase 3 | Completed | Bristol-Myers Squibb | 734 | 2009-07-20 | 2019-12-02 |
| First Line Hepato Cellular Carcinoma (HCC) Brivanib, Placebo, Sorafenib - Hepato Cellular Carcinoma (HCC) | Phase 3 | Completed | Bristol-Myers Squibb | 1714 | 2009-05-01 | 2016-10-17 |
| Comparison of Brivanib and Best Supportive Care to Placebo for Treatment of Liver Cancer for Those Subjects Who Have Failed Sorafenib Treatment Brivanib, Placebo, Best Supportive Care - Liver Cancer | Phase 3 | Completed | Bristol-Myers Squibb | 587 | 2009-02-17 | 2019-10-09 |
| Cetuximab With or Without Brivanib in Treating Patients With K-Ras Wild Type Tumours and Metastatic Colorectal Cancer cetuximab, brivanib alaninate - Colorectal Cancer | Phase 3 | Completed | NCIC Clinical Trials Group | 750 | 2008-05-12 | 2023-08-04 |
Carcinoma, Hepatocellular (2) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Liver Neoplasms (1) · Rectal Neoplasms (1)
Bristol-Myers Squibb (4) · NCIC Clinical Trials Group (1)
Canada (4) · China (4) · South Korea (4) · Taiwan (4) · Argentina (3) · France (3) · Hong Kong (3) · Italy (3) · Japan (3) · Spain (3) · United States (3) · Australia (2) · Belgium (2) · Brazil (2) · Germany (2)
PMID 23690424, PMID 23980084, PMID 23980090, PMID 28131794, PMID 30466310, PMID 34052255, PMID 40215447