6 completed, 5 not yet recruiting, 1 active not recruiting. 12 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 12 | Completed 6, Not yet recruiting 5, Active not recruiting 1 |
Follow Box Breathing: new trials by email Literature Review of Box Breathing trials Research Report on Box Breathing
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Effects of Four Brief Breathwork and Mindfulness Interventions on Anxiety and Psychological Flexibility: A 4-Arm RCT Box Breathing, Cyclic Sighing, Mindfulness AH Exhalation - Anxiety, Psychological Flexibility | Not applicable | Not yet recruiting | Valencian International University (VIU) | 240 | 2027-01-01 | 2026-06-04 |
| Effect of Box Breathing Before Chest Tube Removal After Open-Heart Surgery Box breathing - Open-Heart Surgery | Not applicable | Not yet recruiting | Mersin University | 86 | 2026-10-01 | 2026-09-11 |
| Box Breathing Versus Foot Reflexology on Physiological and Psychological Stress Indicators in Emergency Physicians Box Breathing, Foot Reflexology - Stress | Not applicable | Not yet recruiting | Cairo University | 54 | 2026-07-20 | 2026-07-15 |
| Comparison of Box Breathing and Rhythmic Breathing Techniques in Patients With Asthma Box Breathing, Rhythmic Breathing - Asthma (Diagnosis) | Not applicable | Not yet recruiting | Riphah International University | 36 | 2026-07-01 | 2026-07-21 |
| How Can We Help? Wellbeing Interventions for Choral Music Ensembles Box breathing, Magnify, Emotion regulation through choral literature - Anxiety, Well-Being (Psychological Flourishing) | Not applicable | Not yet recruiting | Jess Walls | 200 | 2026-01-01 | 2025-12-29 |
| Three Breathing Techniques for Heart Rate Variability, Attention, Reaction Time, and Anxiety Mindfulness Breathing, Box Breathing, Nadi Shodhana Pranayama - Breathing Exercises, Healthy Volunteers | Not applicable | Completed | Atlas University | 48 | 2025-09-01 | 2026-09-11 |
| Stress Management Program Cyclic Sighing Breathing, Box Breathing, Hypnosis - Stress, Anxiety | Not applicable | Active not recruiting | Stanford University | 80 | 2025-03-12 | 2026-09-30 |
| Comparative Effects of Wim Hoff Method and Box Breathing Method in Mild COPD Box Breathing, Wim Hoff Breathing Technique - COPD | Not applicable | Completed | Riphah International University | 60 | 2025-01-01 | 2026-04-01 |
| Comparative Effect of Box Breathing And Buteyko Breathing on Pulmonary Functions in Asthma Buteyko Breathing, Box breathing - Asthma (Diagnosis), Breathing Exercises | Not applicable | Completed | Riphah International University | 36 | 2024-12-17 | 2025-08-24 |
| The Effect of Breathing on Cognitive Performance and Stress Box Breathing, Prolonged Exhalation, Normal Breathing - Stress, Acute Stress Reaction | Not applicable | Completed | Texas State University | 66 | 2024-08-01 | 2025-05-22 |
| Anti-Stress Intervention Among Physicians Study Box Breathing, Breathing and Mindfulness Exercise, Everyday life control - Stress, Psychological, Burnout, Psychological | Not applicable | Completed | Charite University, Berlin, Germany | 145 | 2024-04-15 | 2024-12-10 |
| Psychophysiological Effects of Controlled Respiration and Mindfulness Mindfulness Meditation, Cyclic Sighing Breathing, Box Breathing - Stress, Physiological, Stress, Emotional | Not applicable | Completed | Stanford University | 108 | 2020-06-02 | 2022-05-06 |
Anxiety Disorders (6) · Asthma (2) · Disease (2) · Stress, Psychological (2) · Burnout, Psychological (1) · Dyspnea (1) · Occupational Stress (1) · Pain (1) · Pulmonary Disease, Chronic Obstructive (1) · Respiratory Aspiration (1) · Sleep Initiation and Maintenance Disorders (1) · Stress Disorders, Traumatic, Acute (1) · Subjective Stress (1)
Riphah International University (3) · Stanford University (2) · Atlas University (1) · Cairo University (1) · Charite University, Berlin, Germany (1) · Jess Walls (1) · Mersin University (1) · Texas State University (1) · Valencian International University (VIU) (1)
United States (4) · Pakistan (3) · Turkey (Türkiye) (2) · Egypt (1) · Germany (1)
Andrew Huberman, Ph.D. (1) · David Spiegel, M.D. (1) · David Spiegel, MD (1) · Hany Ezzat Obaya, PhD (1) · Humera Ayub, MS-CPPT (1) · Jane Kuehne, PhD (1) · Manuela Kogon, M.D. (1) · Mohamed Ahmed Khatab, PhD (1) · Salma Ibrahim Al Ghitany, PhD (1) · Valentin M Vetter, MD (1)
PMID 16344363, PMID 18778321, PMID 21763472, PMID 28229114, PMID 29486547, PMID 35049605, PMID 37628548