Bone Marrow Purging: Clinical Trials

7 trials of Bone Marrow Purging, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

3 recruiting, 1 active not recruiting, 1 completed, 1 terminated. 4 Phase 1, 2 Phase 3, 1 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 14Recruiting 2, Completed 1, Unknown 1
Phase 32Active not recruiting 1, Terminated 1
Phase 21Unknown 1

Follow Bone Marrow Purging: new trials by email Literature Review of Bone Marrow Purging trials Research Report on Bone Marrow Purging

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant
Biospecimen Collection, Electronic Health Record Review, Haploidentical Hematopoietic Cell Transplantation - Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia
Phase 1RecruitingCity of Hope Medical Center462026-05-082026-07-28
Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) Following Stem Cell Transplantation for the Treatment of Intermediate or High Grade B-cell Non-Hodgkin Lymphoma
Anti-CD19-CAR CMV-specific T-lymphocytes, Autologous Hematopoietic Stem Cell Transplantation, Multi-peptide CMV-Modified Vaccinia Ankara Vaccine - B-Cell Non-Hodgkin Lymphoma, Diffuse Large B-Cell Lymphoma
Phase 1RecruitingCity of Hope Medical Center152023-08-012026-02-23
Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome
Biospecimen Collection, Bone Marrow Aspiration, Busulfan - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Phase 3Active not recruitingChildren's Oncology Group662023-03-152026-07-30
Cord Blood Transplantation With Myeloablative Conditioning and Post-transplant Cyclophosphamide (COmPACt Study)
CB transplantation - Cord Blood Transplantation, Hematological Malignancies
RecruitingFondazione Policlinico Universitario Agostino Gemelli IRCCS102019-03-142025-04-09
Stem Cell Therapy for Patients With Focal Segmental Glomerulosclerosis
Bone marrow stem cell - Focal Segmental Glomerulosclerosis, Chronic Kidney Diseases
Phase 1CompletedUniversidade Federal do Rio de Janeiro52015-06-252020-01-28
Study of ASC-101 in Patients With Hematologic Malignancies Who Receive Dual-cord Umbilical Cord Blood Transplantation
Fludarabine, Clofarabine, Busulfan, ATG, TBI (Myeloablative), Fludarabine, Melphalan, ATG (Reduced Intensity) - Blood And Marrow Transplantation, Leukemia
Phase 1 / Phase 2UnknownTargazyme, Inc.252013-11-012013-11-18
Dose-reduced Versus Standard Conditioning in MDS/sAML
Reduced Intensity Conditioning, Myeloablative conditioning - Myelodysplastic Syndromes, Secondary Acute Myeloid Leukemia
Phase 3TerminatedEuropean Society for Blood and Marrow Transplantation1292004-05-012015-04-03

Conditions studied

Myelodysplastic Syndromes (4)  ·  Hodgkin Disease (2)  ·  Leukemia, Myeloid, Acute (2)  ·  Lymphoma, Non-Hodgkin (2)  ·  Precursor Cell Lymphoblastic Leukemia-Lymphoma (2)  ·  Glomerulosclerosis, Focal Segmental (1)  ·  Hematologic Neoplasms (1)  ·  Leukemia (1)  ·  Leukemia, Biphenotypic, Acute (1)  ·  Leukemia, Lymphocytic, Chronic, B-Cell (1)  ·  Leukemia, Myeloid, Accelerated Phase (1)  ·  Leukemia, Myeloid, Chronic-Phase (1)  ·  Lymphoma (1)  ·  Lymphoma, B-Cell (1)  ·  Lymphoma, Large B-Cell, Diffuse (1)

Sponsors

City of Hope Medical Center (2)  ·  Children's Oncology Group (1)  ·  European Society for Blood and Marrow Transplantation (1)  ·  Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1)  ·  Targazyme, Inc. (1)  ·  Universidade Federal do Rio de Janeiro (1)

Countries

United States (4)  ·  Italy (2)  ·  Australia (1)  ·  Brazil (1)  ·  Canada (1)  ·  Germany (1)  ·  Netherlands (1)  ·  Russia (1)

Top investigators

Afanasyer Boris (1)  ·  Alex Herrera (1)  ·  Allione Bernardino (1)  ·  Augustin Ferrant, MD (1)  ·  Axel R Zander, MD (1)  ·  Dietger Niederwieser, MD (1)  ·  Domink Heim, Prof. (1)  ·  Elizabeth Shpall, MD (1)  ·  Gerhard Behre (1)  ·  Ghulam J Mufti, MD (1)  ·  Giorgio Lambertenghi Deliliers (1)  ·  Heather J Symons (1)  ·  Kai Hubel (1)  ·  Kathrin Haifa Al-Ali, MD (1)  ·  Liisa Volin, MD (1)

Results publications

PMID 39015674

NIH funding

P30CA033572 (2), 2005 (1), P50CA107399 (1), U10CA180886 (1)