6 recruiting, 3 completed, 2 active not recruiting, 2 not yet recruiting. 11 Not applicable, 4 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 3, Recruiting 3, Active not recruiting 2, Not yet recruiting 2, Terminated 1 |
| Phase 3 | 4 | Recruiting 3, Suspended 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Best Medical Management: new trials by email Literature Review of Best Medical Management trials Research Report on Best Medical Management
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intra-arterial Thrombolysis For Acute Ischemic Stroke With Medium Vessel Occlusion Recombinant Tissue Plasminogen Activator (rt-PA), Intra-arterial Thrombolysis, Best Medical Management - Medium Vessel Occlusion, Ischemic Stroke, Acute | Phase 3 | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 372 | 2026-09-19 | 2026-09-23 |
| Endovascular Therapy for Acute Basilar Artery Occlusion With Large Ischemic Core Endovascular Therapy, Best Medical Management - Acute Ischemic Stroke, Basilar Artery Occlusion | Not applicable | Recruiting | The First Affiliated Hospital of University of Science and Technology of China | 256 | 2026-08-01 | 2026-10-13 |
| The Efficacy and Safety of Endovascular Treatment for Acute Mild Basilar Artery Occlusion Endovascular Recanalization Strategy, Best Medical Management - Acute Mild Basilar Artery Occlusion, Basilar Artery Occlusion | Not applicable | Not yet recruiting | Feng Gao | 230 | 2026-03-01 | 2026-02-05 |
| The Efficacy and Safety of Endovascular Therapy for Acute Ischemic Stroke Due to Large Core Infarction Endovascular Recanalization Strategy, Best Medical Management - Acute Basilar Artery Occlusion, Endovascular Therapy | Not applicable | Not yet recruiting | Beijing Tiantan Hospital | 308 | 2026-01-01 | 2026-01-12 |
| Early Antiplatelet Administration After Intravenous Thrombolysis for Acute Ischemic Stroke (TREND-IVT) Aspirin, Placebo, Best medical management - Acute Ischemic Stroke, Cerebral Infarction | Phase 3 | Recruiting | Capital Medical University | 1184 | 2024-11-07 | 2026-09-24 |
| Remote Ischemic Conditioning for Acute Ischemic Stroke Treated With Mechanical Thrombectomy（RECAST-MT） 14-day remote ischemic conditioning, 30-day remote ischemic conditioning, Endovascular thrombectomy - Acute Ischemic Stroke, Anterior Circulation Brain Infarction | Phase 3 | Recruiting | Capital Medical University | 2105 | 2024-09-23 | 2025-12-10 |
| Endovascular Therapy Versus Best Medical Treatment for Acute Large Vessel Occlusion Stroke With Low NIHSS Endovascular therapy, Best medical management - Acute Ischemic Stroke, Mild Neurocognitive Disorder | Not applicable | Recruiting | First Affiliated Hospital of Wannan Medical College | 264 | 2024-01-21 | 2026-09-25 |
| Rescue Endovascular Therapy for Progressive Acute Mild Ischemic Stroke With Large Vascular Occlusion Endovascular therapy, Best medical management - Stroke, Ischemic, Cerebrovascular; Disorder, Occlusive | Not applicable | Recruiting | First Affiliated Hospital of Wannan Medical College | 272 | 2024-01-04 | 2026-04-30 |
| Efficacy and Safety of Endovascular Recanalization for Acute Basilar Artery Occlusion With Extended Time Window (ANGEL-BAO) Best medical management, Endovascular treatment - Acute Ischemic Stroke, Basilar Artery Occlusion | Not applicable | Active not recruiting | Beijing Tiantan Hospital | 224 | 2023-11-16 | 2026-10-22 |
| Intra-arterial Recombinant Human TNK Tissue-type Plasminogen Activator (rhTNK-tPA) Thrombolysis for Acute Large Vascular Occlusion After Successful Mechanical Thrombectomy Recanalization Recombinant Human tenecteplase Tissue-type Plasminogen Activator (rhTNK-tPA), Best Medical Management - Ischemic Stroke, Acute | Phase 4 | Unknown | Beijing Tiantan Hospital | 256 | 2023-02-16 | 2024-03-19 |
| REperfusion With P2Y12 Inhibitors in Addition to mEchanical thRombectomy for perFUsion Imaging Selected Acute Stroke patiEnts Cangrelor, best medical management - Acute Ischemia | Phase 3 | Suspended | Fondation Ophtalmologique Adolphe de Rothschild | 368 | 2022-03-02 | 2026-09-25 |
| Early RRT in AKI After Cardiac Surgery Renal replacement therapy, Best medical management - Acute Kidney Injury | Not applicable | Terminated | Seoul National University Hospital | 44 | 2021-12-24 | 2026-02-12 |
| Endovascular Treatment for Acute Basilar Artery Occlusion endovascular treatment, best medical management - Basilar Artery Occlusion, Acute Cerebrovascular Accident | Not applicable | Completed | The First Affiliated Hospital of University of Science and Technology of China | 340 | 2021-02-21 | 2022-09-15 |
| Study of Endovascular Therapy in Acute Anterior Circulation Large Vessel Occlusive Patients With a Large Infarct Core Best medical management, Endovascular therapy - Acute Ischemic Stroke | Not applicable | Completed | Beijing Tiantan Hospital | 456 | 2020-10-02 | 2023-10-17 |
| Procedure for Duodenum to Ileal Diversion to Treat Type 2 Diabetes Magnet Anastomosis System, Best Medical Management - Type 2 Diabetes, Obesity | Not applicable | Active not recruiting | GI Windows, Inc. | 15 | 2019-09-23 | 2026-07-06 |
| Metabolic Surgery Versus Medical Management for Resolution of Type II Diabetes Laboratory evaluations, sleep study, Best Medical Management, Roux-en-Y gastric bypass surgery - Obesity, Type 2 Diabetes Mellitus | Not applicable | Completed | David Bradley MD | 120 | 2010-01-01 | 2015-04-21 |
Ischemic Stroke (11) · Diabetes Mellitus, Type 2 (2) · Obesity (2) · Acute Kidney Injury (1) · Bites and Stings (1) · Brain Infarction (1) · Cerebral Infarction (1) · Neurocognitive Disorders (1) · Stroke (1)
Beijing Tiantan Hospital (4) · Capital Medical University (2) · First Affiliated Hospital of Wannan Medical College (2) · The First Affiliated Hospital of University of Science and Technology of China (2) · David Bradley MD (1) · Feng Gao (1) · Fondation Ophtalmologique Adolphe de Rothschild (1) · GI Windows, Inc. (1) · Seoul National University Hospital (1) · The First Affiliated Hospital with Nanjing Medical University (1)
China (12) · Argentina (1) · France (1) · South Korea (1) · United States (1)
Feng Gao, MD (2) · Asem Ali, MD (1) · Feng Gao (1) · Ho Young Hwang, MD, PhD (1) · Kai Wang, PhD (1) · Rudolf H Buxhoeveden (1) · Sheng Liu, Professor (1) · Wei Hu, PhD (1) · Zhiming Zhou, PhD (1) · Zhongrong Miao, MD, PhD (1) · Zhongrong Miao, PhD (1)
PMID 28174194, PMID 32166195, PMID 33028663, PMID 35102797, PMID 35858168, PMID 36239644, PMID 36762852, PMID 38010691, PMID 38178887, PMID 38228387, PMID 38638180, PMID 39038096, PMID 39160092, PMID 39332900, PMID 39357896, PMID 39652807, PMID 39972662, PMID 40013350, PMID 40079327, PMID 40280761, PMID 40340582, PMID 40616323, PMID 40674670, PMID 40854041, PMID 41290408, PMID 41317114, PMID 41439308, PMID 41469196, PMID 41565354, PMID 41611344, PMID 41641580, PMID 41717940, PMID 41914357, PMID 41956819, PMID 42413994, PMID 42419771