3 recruiting, 2 completed, 2 withdrawn, 1 not yet recruiting. 6 Phase 4, 2 Phase 3, 1 Early Phase 1, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 6 | Recruiting 2, Withdrawn 2, Not yet recruiting 1, Unknown 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
| Early Phase 1 | 1 | Terminated 1 |
| Phase 1 | 1 | Completed 1 |
Follow Benzylpenicillin: new trials by email Literature Review of Benzylpenicillin trials Research Report on Benzylpenicillin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Single Dose of Intravenous Penicillin as an Adjunct to Oral Penicillin in the Treatment of Acute Tonsillitis, Peritonsillar Phlegmon, and Peritonsillar Abscess Benzylpenicillin, Isotonic NaCl (Placebo) - Acute Tonsillitis, Peritonsillar Abscess | Phase 4 | Not yet recruiting | Tejs Ehlers Klug | 154 | 2026-10-01 | 2026-10-26 |
| Continuous Antibiotic Infusion In Children Benzylpenicillin - Infection | Phase 3 | Recruiting | Tampere University Hospital | 150 | 2026-04-21 | 2026-05-08 |
| Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia Penicillin G_1200mg, cloxacillin - Staphylococcus Aureus Bacteraemia, Staphylococcal Bacteraemia | Phase 4 | Recruiting | Region Skane | 420 | 2025-03-10 | 2026-04-30 |
| Staphylococcus Aureus Network Adaptive Platform Trial Cefazolin, Penicillin, Clindamycin - Staphylococcus Aureus Bacteremia | Phase 4 | Recruiting | University of Melbourne | 8000 | 2022-02-16 | 2026-05-06 |
| Closed-loop Control of Penicillin Delivery Microneedle array, Microneedle array and closed-loop control of penicillin delivery, Penicillin G_1200mg - Healthy Volunteers | Phase 1 | Completed | Imperial College London | 6 | 2019-11-05 | 2024-07-10 |
| Penicillin Against Flucloxacillin Treatment Evaluation Benzylpenicillin, Flucloxacillin - Staphylococcus Aureus | Phase 4 | Withdrawn | The University of Queensland | 2019-07-01 | 2022-11-16 | |
| Therapeutic Drug Monitoring and Continuous Infusion of Beta-lactam Antibiotics in Patients With Bacteraemia Continuous infusion of beta-lactam antibiotics ., Therapeutic drug monitoring of beta-lactam antibiotics. - Bacteremia | Phase 4 | Withdrawn | Sara Thønnings | 2017-10-01 | 2023-03-29 | |
| Patients Response to Early Switch To Oral:Osteomyelitis Study oral antibiotics, intravenous antibiotics - Osteomyelitis | Early Phase 1 | Terminated | Julio Ramirez | 11 | 2014-03-06 | 2021-04-06 |
| Procalcitonin as a Marker of Antibiotic Therapy in Patients With Lower Respiratory Tract Infections PCT-level, Antibiotic treatment based on PCT-level - Pneumonia, Acute Exacerbation of Chronic Obstructive Airways Disease | Phase 4 | Unknown | Holbaek Sygehus | 55 | 2013-10-01 | 2014-08-15 |
| Evaluation of Skin Testing Reagents for Penicillin Allergy Penicillin skin test kit - History of IgE Dependent Reaction to a Penicillin Product | Phase 3 | Completed | AllerQuest LLC | 481 | 2012-12-01 | 2017-01-04 |
Bacteremia (2) · Osteomyelitis (2) · Staphylococcal Infections (2) · Infections (1) · Peritonsillar Abscess (1) · Pneumonia (1) · Sepsis (1) · Toxemia (1)
AllerQuest LLC (1) · Holbaek Sygehus (1) · Imperial College London (1) · Julio Ramirez (1) · Region Skane (1) · Sara Thønnings (1) · Tampere University Hospital (1) · Tejs Ehlers Klug (1) · The University of Queensland (1) · University of Melbourne (1)
United States (3) · Australia (2) · Denmark (2) · Sweden (2) · United Kingdom (2) · Canada (1) · Finland (1) · France (1) · Germany (1) · Israel (1) · Japan (1) · Netherlands (1) · New Zealand (1) · Singapore (1) · South Africa (1)
Alison H Holmes, MD MPH MBBS (1) · David Paterson (1) · David Seligson, MD (1) · Hans Ibsen, M.D., D.M.Sc (1) · Julio Ramirez, MD (1) · Malin Hagstrand Aldman, PhD, MD (1) · N. Franklin Adkinson, Jr., MD (1) · Prof Joshua Davies (1) · Prof Steven Tong (1) · Tejs E Klug, MD, DMSc (1)
PMID 15276398, PMID 15840453, PMID 19588358, PMID 22530208, PMID 39934879, PMID 41433510, PMID 42308484, PMID 42309115, PMID 4902833, PMID 8948280
2023 (1), 2025 (1)