Bendroflumethiazide: Clinical Trials

8 trials of Bendroflumethiazide, newest first

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5 completed, 1 recruiting, 1 suspended, 1 unknown. 3 Phase 1, 2 Not applicable, 2 Phase 4.

By phase and status

PhaseTrialsStatus
Phase 13Completed 2, Recruiting 1
Not applicable2Completed 1, Unknown 1
Phase 42Completed 1, Suspended 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Mechanisms of Diuretic Resistance in Heart Failure, Aim 2
Placebo, Amiloride, Bendroflumethiazide - Heart Failure
Phase 1RecruitingYale University502023-08-102026-09-08
Coronavirus (COVID-19) ACEi/ARB Investigation
Thiazide or Thiazide-like diuretics, Calcium Channel Blockers, ACE inhibitor - Hypertension, COVID-19
Phase 4SuspendedNational University of Ireland, Galway, Ireland24142020-04-302020-06-30
ACEI or ARB and COVID-19 Severity and Mortality in US Veterans
ACEI/ARB, Non-ACEI/ARB, ACEI - Hypertension, COVID
CompletedUniversity of Utah222132020-01-192021-04-28
Fed Study of Nadolol/Bendroflumethiazide Tablets 80 mg/5 mg and Corzide® Tablets 80 mg/5 mg
Nadolol/Bendroflumethiazide Tablets 80 mg/5 mg, Corzide® Tablets 80 mg/5 mg - Healthy
Phase 1CompletedMylan Pharmaceuticals Inc422006-08-012024-04-23
Double Blind Crossover Comparison of Diuretics in the Young
Bendroflumethiazide 2.5mg - 5mg, Amiloride 20-40mg, Spironolactone 50-100mg - Low-Renin Hypertension
Not applicableUnknownUniversity of Cambridge302006-08-012007-02-01
Fasting Study of Nadolol/Bendroflumethiazide Tablets 80 mg/5 mg and Corzide® Tablets 80 mg/5 mg
Nadolol/Bendroflumethiazide Tablets 80 mg/5 mg, Corzide® Tablets 80 mg/5 mg - Healthy
Phase 1CompletedMylan Pharmaceuticals Inc662006-07-012024-04-23
Pathophysiological Mechanisms of Hypertensive LVH:Optimising Regression
Bendroflumethiazide 2.5mg OD; Amlodipine 10mg OD, Valsartan 160mg OD; Moxonidine 400mcg OD - Hypertension, Left Ventricular Hypertrophy
Not applicableCompletedUniversity of Leeds422003-09-012012-08-16
A Randomised, Parallel-group, Double-blind, Double-dummy Study to Compare the Effects of Lacidipine Versus Bendrofluazide on Markers of Platelet Activation and Haemorheological Factors in Hypertensive Patients
Lacidipine, Bendrofluazide, Placebo - Hypertension
Phase 4CompletedBoehringer Ingelheim261997-12-012014-09-10

Conditions studied

Hypertension (5)  ·  COVID-19 (1)  ·  Cardiovascular Diseases (1)  ·  Coronavirus Infections (1)  ·  Heart Failure (1)  ·  Hypertrophy, Left Ventricular (1)

Sponsors

Mylan Pharmaceuticals Inc (2)  ·  Boehringer Ingelheim (1)  ·  National University of Ireland, Galway, Ireland (1)  ·  University of Cambridge (1)  ·  University of Leeds (1)  ·  University of Utah (1)  ·  Yale University (1)

Countries

United States (4)  ·  United Kingdom (2)  ·  Ireland (1)

Top investigators

James D Carlson, Pharm. D. (2)  ·  Adam P Bress, PharmD, MS (1)  ·  Jeffrey Testani (1)  ·  John P Greenwood, MBChB, PhD (1)  ·  John William McEvoy, MBBCh MHS (1)  ·  Morris J Brown, Proffessor (1)

Results publications

PMID 17389264, PMID 33891615

NIH funding

R01DK130997 (1)