7 completed, 1 active not recruiting, 1 recruiting. 9 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 9 | Completed 7, Active not recruiting 1, Recruiting 1 |
| Phase 2 | 4 | Completed 3, Active not recruiting 1 |
Follow Belatacept: new trials by email Literature Review of Belatacept trials Research Report on Belatacept
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment of Antibody-Mediated Rejection (ABMR) With CarBel Carfilzomib, Belatacept - Kidney Transplant Rejection | Phase 1 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 25 | 2026-05-27 | 2026-10-23 |
| Carfilzomib and Belatacept for Desensitization carfilzomib, belatacept, Bone marrow aspiration - Highly Sensitized Prospective Kidney Transplant Recipients | Phase 1 / Phase 2 | Active not recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 21 | 2021-12-28 | 2026-04-08 |
| Daratumumab and Belatacept for Desensitization daratumumab, belatacept, Bone marrow aspiration - Highly Sensitized Prospective Kidney Transplant Recipients | Phase 1 / Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 19 | 2021-11-01 | 2026-10-23 |
| Treg Modulation With CD28 and IL-6 Receptor Antagonists lulizumab pegol, antithymocyte globulin (rabbit), methylprednisolone - Living-Donor Kidney Transplant, Kidney Transplant Recipients | Phase 1 / Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 24 | 2019-12-11 | 2026-09-24 |
| Tolerance by Engaging Antigen During Cellular Homeostasis Donor-derived Mesenchymal Stromal Cells, alemtuzumab, belatacept - Kidney Transplantation, Renal Transplantation | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 16 | 2018-07-30 | 2026-10-29 |
| A Study Using Healthy Volunteers Comparing Belatacept Which Has Been Manufactured By 2 Different Processes belatacept - Healthy Volunteers | Phase 1 | Completed | Bristol-Myers Squibb | 84 | 2017-12-04 | 2019-07-24 |
| Renal Allograft Tolerance Through Mixed Chimerism (Belatacept) Belatacept, ATG, Rituximab - Kidney Failure, Chronic, Renal Insufficiency | Phase 1 | Completed | Massachusetts General Hospital | 2 | 2015-02-01 | 2021-10-25 |
| Subcutaneous Pharmacokinetics of Belatacept belatacept, Placebo - Transplantation | Phase 1 | Completed | Bristol-Myers Squibb | 153 | 2007-12-01 | 2016-09-22 |
| Phase I/II Multiple-Dose LEA29Y vs CTLAG4Ig vs Placebo in Rheumatoid Arthritis Belatacept, Abatacept - Rheumatoid Arthritis | Phase 1 / Phase 2 | Completed | Bristol-Myers Squibb | 210 | 2016-09-16 |
Arthritis, Rheumatoid (1) · Kidney Failure, Chronic (1) · Renal Insufficiency (1)
National Institute of Allergy and Infectious Diseases (NIAID) (5) · Bristol-Myers Squibb (3) · Massachusetts General Hospital (1)
United States (9) · Belgium (1) · Canada (1) · France (1) · Germany (1) · Ireland (1) · Netherlands (1) · Switzerland (1) · United Kingdom (1)
Allan D. Kirk, M.D., Ph.D. (1) · Annette M. Jackson, PhD (1) · Flavio G. Vincenti (1) · Flavio Vincenti, M.D. (1) · Scott Sanoff, MD, Ph.D. (1) · Sindhu Chandran, M.D. (1) · Stuart J Knechtle, M.D. (1) · Stuart J. Knechtle, MD (1) · Tatsuo Kawai, MD PhD (1)
UM1AI109565 (2)