8 completed, 5 terminated. 9 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 6, Terminated 3 |
| Phase 1 | 3 | Completed 2, Terminated 1 |
| Phase 3 | 1 | Terminated 1 |
Follow becatecarin: new trials by email Literature Review of becatecarin trials Research Report on becatecarin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| XL119 Versus 5-Fluorouracil (5-FU) Plus Leucovorin (LV) in Subjects With Advanced Biliary Tumors becatecarin, 5-Fluorouracil Plus Leucovorin - Biliary Tract Cancer | Phase 3 | Terminated | Helsinn Healthcare SA | 248 | 2004-09-01 | 2009-01-14 |
| Rebeccamycin Analog in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia, or Chronic Myelogenous Leukemia becatecarin, laboratory biomarker analysis - Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Phase 1 | Completed | National Cancer Institute (NCI) | 40 | 2004-05-01 | 2013-01-23 |
| Rebeccamycin Analog and Oxaliplatin in Treating Patients With Refractory Solid Tumors becatecarin, oxaliplatin, pharmacological study - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Terminated | National Cancer Institute (NCI) | 15 | 2004-05-01 | 2013-01-10 |
| Rebeccamycin Analog as Second-Line Therapy in Treating Patients With Limited-Stage or Extensive-Stage Small Cell Lung Cancer That Relapsed After Previous First-Line Chemotherapy becatecarin - Extensive Stage Small Cell Lung Cancer, Limited Stage Small Cell Lung Cancer | Phase 2 | Terminated | National Cancer Institute (NCI) | 21 | 2004-04-01 | 2014-05-23 |
| Rebeccamycin Analogue in Treating Patients With Refractory Stage III or Stage IV Ovarian Epithelial Cancer becatecarin - Ovarian Cancer | Phase 2 | Terminated | Northwestern University | 2000-07-01 | 2012-06-11 | |
| Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma becatecarin - Brain and Central Nervous System Tumors, Lymphoma | Phase 2 | Completed | National Cancer Institute (NCI) | 200 | 2000-07-01 | 2013-02-05 |
| Rebeccamycin Analog in Treating Patients With Advanced Kidney Cancer becatecarin - Kidney Cancer | Phase 2 | Completed | Barbara Ann Karmanos Cancer Institute | 2000-06-01 | 2013-04-05 | |
| Two Rebeccamycin Analogue Regimens in Treating Patients With Advanced or Recurrent Non-small Cell Lung Cancer becatecarin - Lung Cancer | Phase 2 | Completed | Case Comprehensive Cancer Center | 42 | 2000-05-01 | 2010-06-10 |
| Rebeccamycin Analogue in Treating Women With Stage IIIB or Stage IV Breast Cancer becatecarin, laboratory biomarker analysis - Male Breast Cancer, Recurrent Breast Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 42 | 2000-03-01 | 2013-02-01 |
| Rebeccamycin Analog in Treating Patients With Metastatic or Locally Recurrent Colorectal Cancer becatecarin - Colorectal Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 37 | 2000-02-01 | 2013-02-11 |
| Rebeccamycin Analog and Cisplatin With or Without Filgrastim in Treating Patients With Advanced Cancer filgrastim, becatecarin, cisplatin - Lymphoma, Small Intestine Cancer | Phase 1 | Completed | National Cancer Institute (NCI) | 40 | 1999-10-01 | 2013-02-11 |
| Rebeccamycin Analogue in Treating Patients With Advanced Liver and/or Biliary Cancer becatecarin - Extrahepatic Bile Duct Cancer, Gallbladder Cancer | Phase 2 | Terminated | Case Comprehensive Cancer Center | 72 | 1999-04-01 | 2010-06-11 |
| Rebeccamycin Analog in Treating Children With Relapsed or Refractory Neuroblastoma becatecarin - Neuroblastoma | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 30 | 1999-01-01 | 2013-06-25 |
Bile Duct Neoplasms (2) · Burkitt Lymphoma (2) · Gallbladder Neoplasms (2) · Lymphoma (2) · Neuroblastoma (2) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (2) · Anemia, Refractory, with Excess of Blasts (1) · Astrocytoma (1) · Biliary Tract Neoplasms (1) · Blast Crisis (1) · Breast Neoplasms (1) · Breast Neoplasms, Male (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Ovarian Epithelial (1)
National Cancer Institute (NCI) (7) · Case Comprehensive Cancer Center (2) · Barbara Ann Karmanos Cancer Institute (1) · Helsinn Healthcare SA (1) · Memorial Sloan Kettering Cancer Center (1) · Northwestern University (1)
United States (13) · Canada (2) · Australia (1) · Belgium (1) · France (1) · Germany (1) · Hungary (1) · Italy (1) · Netherlands (1) · New Zealand (1) · Poland (1) · Puerto Rico (1) · Russia (1) · Spain (1) · Switzerland (1)
Afshin Dowlati, MD (3) · Afshin Dowlati (2) · Anne-Marie Langevin, MD (1) · David A. Fishman, MD (1) · Francis Giles (1) · Harold Burstein (1) · Lisa Hammond, MD (1) · Sridhar Mani, MD (1) · Tanya Trippett, MD (1) · Ulka N. Vaishampayan, MD (1)
P30CA043703 (3), U01CA062502 (3), U01CA063200 (2), P30CA022453 (1), U01CA062461 (1), U01CA062487 (1)