2 completed, 2 recruiting, 1 enrolling by invitation, 1 not yet recruiting. 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 1 | Not yet recruiting 1 |
Follow Aztreonam-Avibactam: new trials by email Literature Review of Aztreonam-Avibactam trials Research Report on Aztreonam-Avibactam
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Aztreonam-Avibactam in Immunocompromised Hosts Aztreonam-Avibactam, Ceftazidime-Avibactam Plus Aztreonam - Enterobacteriaceae Infections, Carbapenem-Resistant Enterobacteriaceae Infection | Recruiting | Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno | 814 | 2026-10-14 | 2026-10-22 | |
| Targeted Versus Standard Peri-operative Antibiotic Prophylaxis in Patients Colonized With Carbapenemase Producing Enterobacterales Undergoing Liver Transplantation Ceftazidime - Avibactam ( CAZ-AVI), Meropenem-Vaborbactam, Imipenem+Relebactam - Liver Transplant, Carbapenem-resistant Enterobacterales | Phase 3 | Not yet recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 168 | 2026-10-01 | 2026-08-12 |
| Real-World Effectiveness of Aztreonam-Avibactam Against MBL-Producing CRE Aztreonam-Avibactam - Complicated Intra-Abdominal Infections, cIAIs, Hospital-acquired Pneumonia (HAP) | Recruiting | Sir Run Run Shaw Hospital | 100 | 2025-12-25 | 2026-03-23 | |
| Real-world Multicentre Study of AZtreonam-AVIbactam Treatment With Infections or Suspected Infections Caused by Multidrug-resistant Gram-negative Bacteria Aztreonam-Avibactam - Critical Care, Infection | Enrolling by invitation | French Society for Intensive Care | 100 | 2024-01-01 | 2025-09-16 | |
| Study to Assess the Pharmacokinetics, Safety and Tolerability of Aztreonam-Avibactam in Healthy Chinese Participants. Aztreonam-Avibactam - Healthy | Phase 1 | Completed | Pfizer | 12 | 2021-08-20 | 2023-07-28 |
| Pharmacokinetic Study of Aztreonam-Avibactam in Severe Renal Impairment Aztreonam-Avibactam - Renal Insufficiency | Phase 1 | Completed | Pfizer | 11 | 2020-08-10 | 2023-07-28 |
Infections (2) · Communicable Diseases (1) · Enterobacteriaceae Infections (1) · Healthcare-Associated Pneumonia (1) · Pneumonia, Ventilator-Associated (1) · Renal Insufficiency (1)
Pfizer (2) · Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno (1) · French Society for Intensive Care (1) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (1) · Sir Run Run Shaw Hospital (1)
China (2) · Argentina (1) · France (1) · Italy (1) · United States (1)
Diego Torres, MD (1) · Maddalena Giannella, MD, PhD (1) · Maximiliano Gabriel Castro, MD (1)
2025 (1)