7 completed. 4 Phase 1, 3 Phase 2.
By phase and status
Follow AZD4017: new trials by email Literature Review of AZD4017 trials Research Report on AZD4017
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
Glucocorticoids and Skin Healing in Diabetes (GC-SHealD) AZD4017, Placebo - Diabetes Mellitus, Type 2 | Phase 2 | Completed | 28 | 2018-04-10 | 2019-03-22 |
Safety and Effectiveness of 11b-Hydroxysteroid Dehydrogenase Type 1 Inhibitor (AZD4017) to Treat Idiopathic Intracranial Hypertension. AZD4017, Placebo - Idiopathic Intracranial Hypertension | Phase 2 | Completed | 31 | 2014-04-25 | 2021-10-27 |
A Phase IIa Study to Assess the Tolerability, Safety, and Efficacy of AZD4017 for Raised Intra-ocular Pressure AZD4017, Placebo - Raised Intraocular Pressure | Phase 2 | Completed | 50 | 2010-12-01 | 2014-02-14 |
Study to Evaluate Methods That Assess the Effect of AZD4017 in Adipose Tissue AZD4017, Placebo - Obesity | Phase 1 | Completed | 15 | 2010-03-01 | 2010-12-10 |
Phase I Study in Healthy Volunteers to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD4017 After Repeated Ascending Oral Doses AZD4017, Placebo - Diabetes Mellitus Type 2 | Phase 1 | Completed | 107 | 2009-02-01 | 2009-09-30 |
Study to Investigate Safety and Tolerability Single Ascending Doses of AZD4017. AZD4017, Placebo - Healthy | Phase 1 | Completed | 56 | 2008-12-01 | 2009-07-02 |
Study to Investigate Safety and Tolerability Single Ascending Doses of AZD4017 AZD4017, Placebo - Healthy | Phase 1 | Completed | 40 | 2008-11-01 | 2009-06-16 |
Conditions studied
Diabetes Mellitus, Type 2 (2) · Obesity (2) · Blindness (1) · Headache (1) · Intracranial Hypertension (1) · Ocular Hypertension (1) · Papilledema (1) · Pseudotumor Cerebri (1) · Tinnitus (1)
Sponsors
AstraZeneca (5) · University of Birmingham (1) · University of Leeds (1)
Countries
Sweden (4) · United Kingdom (3) · Japan (1) · United States (1)
Top investigators
Marianne Hartford, MD PhD (2) · Alexandra Sinclair, MbChb PhD (1) · Heather Bryson, PhD (1) · Per-Anders Jansson, Ass Prof, MD, PhD (1) · Shunji Matsuki (1) · Tony Ho, MD (1)
Results publications
PMID 28923789, PMID 33098644, PMID 36240084, PMID 37740611