7 completed, 2 active not recruiting, 1 recruiting. 4 Not applicable, 4 Phase 2, 1 Early Phase 1, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 4 |
| Phase 2 | 4 | Active not recruiting 2, Completed 1, Recruiting 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 1 | 1 | Completed 1 |
Follow Avmacol: new trials by email Literature Review of Avmacol trials Research Report on Avmacol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Broccoli Extract Supplementation in Older Adults With Alcohol Use Disorder Generally Recognized as Safe - Sulforaphane, Placebo - Alcohol Use Disorder | Not applicable | Completed | Louisiana State University Health Sciences Center in New Orleans | 40 | 2024-01-23 | 2026-04-28 |
| Evaluation of Broccoli Seed and Sprout Extract for Detoxification of Carcinogens in Firefighters Acetaminophen, Biospecimen Collection, Broccoli Sprout/Broccoli Seed Extract Supplement - Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 72 | 2023-12-04 | 2026-09-23 |
| Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers Biospecimen Collection, Broccoli Sprout/Broccoli Seed Extract Supplement, Placebo Administration - Cigarette Smoking-Related Carcinoma | Phase 2 | Recruiting | National Cancer Institute (NCI) | 135 | 2022-09-21 | 2026-11-12 |
| Study of Sulphoraphane in Chronic Kidney Disease Sulforaphane - Chronic Kidney Disease stage3, Chronic Kidney Disease stage4 | Phase 1 | Completed | University of Rochester | 18 | 2022-05-02 | 2024-08-12 |
| Open-Label Trial of Sulforaphane in Premutation Carriers With FXTAS Sulforaphane - Fragile X Associated Tremor/Ataxia Syndrome (Fxtas) (Diagnosis) | Not applicable | Completed | University of California, Davis | 15 | 2021-06-25 | 2023-07-12 |
| Effects of Avmacol® in the Oral Mucosa of Patients Following Curative Treatment for Tobacco-related Head and Neck Cancer Avmacol - Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma (HNSCC) | Not applicable | Completed | University of Pittsburgh | 6 | 2018-07-27 | 2023-04-07 |
| Broccoli Sprout/Broccoli Seed Extract Supplement in Decreasing Toxicity in Heavy Smokers Broccoli Sprout/Broccoli Seed Extract Supplement, Laboratory Biomarker Analysis, Questionnaire Administration - Cigarette Smoking-Related Carcinoma, Tobacco-Related Carcinoma | Early Phase 1 | Completed | National Cancer Institute (NCI) | 49 | 2018-02-20 | 2023-06-28 |
| Sulforaphane for the Treatment of Young Men With Autism Spectrum Disorder Sulforaphane, Placebo - Autism Spectrum Disorder, Autistic Disorder | Phase 2 | Completed | University of North Carolina, Chapel Hill | 48 | 2017-03-01 | 2020-06-04 |
| Bioavailability and Mucosal Bioactivity of Avmacol® in Healthy Volunteers Avmacol - Healthy | Not applicable | Completed | University of Pittsburgh | 10 | 2016-06-16 | 2017-11-13 |
| Sulforaphane in a New Jersey (NJ) Population of Individuals With Autism Sulforaphane, Placebo - Autism, Autistic Disorder | Phase 2 | Active not recruiting | Rutgers, The State University of New Jersey | 48 | 2016-02-01 | 2025-10-29 |
Autism Spectrum Disorder (2) · Autistic Disorder (2) · Alcoholism (1) · Carcinoma in Situ (1) · Child Development Disorders, Pervasive (1) · Disease (1) · Fragile X Tremor Ataxia Syndrome (1) · Head and Neck Neoplasms (1) · Hyperplasia (1) · Inflammation (1) · Neurodevelopmental Disorders (1) · Squamous Cell Carcinoma of Head and Neck (1)
National Cancer Institute (NCI) (3) · University of Pittsburgh (2) · Louisiana State University Health Sciences Center in New Orleans (1) · Rutgers, The State University of New Jersey (1) · University of California, Davis (1) · University of North Carolina, Chapel Hill (1) · University of Rochester (1)
United States (9)
Julie E Bauman (2) · Aline Zaparte, PhD (1) · Dan P Zandberg, MD (1) · Julie Bauman, MD (1) · Laura Politte, M.D. (1) · Malvi Savani (1) · Steven Buyske (1) · Thu H Le, MD, FAHA (1)
P30CA023074 (3), UG1CA242596 (2), 5KL2TR001109-05 (1), N01CN00031 (1), R01DK128677 (1), U24DK132740 (1)