7 completed. 7 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 7 |
| Phase 2 | 3 | Completed 3 |
Follow Ascorbate: new trials by email Literature Review of Ascorbate trials Research Report on Ascorbate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combined Antioxidant Therapy Against Myocardial Reperfusion Injury. Phase I Study. Antioxidant therapy, NaCl 0.9% - Acute Myocardial Infarction, Ischemia-reperfusion Injury | Phase 1 | Completed | University of Chile | 18 | 2022-08-09 | 2024-01-12 |
| High Dose Ascorbate With Preoperative Radiation in Patients With Locally Advanced Soft Tissue Sarcomas Ascorbate - Soft Tissue Sarcoma | Phase 1 / Phase 2 | Completed | Mohammed Milhem | 25 | 2019-06-27 | 2026-06-18 |
| High Dose Ascorbic Acid for Plasma Cell Disorders Ascorbate, Melphalan - Multiple Myeloma | Phase 1 | Completed | Christopher Strouse | 6 | 2019-03-05 | 2025-10-21 |
| A Phase Ib Study Evaluating the Safety and Tolerability of Vitamin C in Patients With Intermediate or High Risk Myelodysplastic Syndrome With TET2 Mutations Vitamin C - Myelodysplastic Syndromes | Phase 1 / Phase 2 | Completed | NYU Langone Health | 4 | 2018-05-01 | 2024-03-27 |
| Gemcitabine, Ascorbate, Radiation Therapy for Pancreatic Cancer, Phase I Ascorbate, Gemcitabine, Radiation therapy - Pancreatic Neoplasms | Phase 1 | Completed | Joseph J. Cullen | 16 | 2014-01-01 | 2025-10-24 |
| A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme Ascorbate, Temozolomide, Radiation therapy - Glioblastoma, GBM | Phase 1 | Completed | Joseph J. Cullen, MD, FACS | 13 | 2013-04-01 | 2024-12-20 |
| A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and Effective Ascorbic Acid + Sorafenib, Sorafenib - Metastatic Hepatocellular Carcinoma, Advanced Liver Cancer | Phase 1 / Phase 2 | Completed | Thomas Jefferson University | 5 | 2012-09-01 | 2025-05-04 |
Carcinoma, Hepatocellular (1) · Glioblastoma (1) · Liver Neoplasms (1) · Multiple Myeloma (1) · Myelodysplastic Syndromes (1) · Myocardial Reperfusion Injury (1) · Neoplasms (1) · Pancreatic Neoplasms (1) · Reperfusion Injury (1) · Sarcoma (1)
Christopher Strouse (1) · Joseph J. Cullen (1) · Joseph J. Cullen, MD, FACS (1) · Mohammed Milhem (1) · NYU Langone Health (1) · Thomas Jefferson University (1) · University of Chile (1)
United States (6) · Chile (1)
Abraham IJ Gajardo, MD, PhD (1) · Christopher Strouse, MD (1) · Daniel A Monti, MD, MBA (1) · John M. Buatti, MD (1) · Joseph J Cullen, MD (1) · Joseph J Cullen, MD, FACS (1) · Mohammad M Abdul Hay, MD (1) · Mohammed Milhem, MBBS (1)
PMID 28366679, PMID 30254147, PMID 38973337
P30CA086862 (1), U01CA140206 (1)