Aprotinin: Clinical Trials

6 trials of Aprotinin, newest first

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3 terminated, 1 completed, 1 recruiting, 1 unknown. 6 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 36Terminated 3, Completed 1, Recruiting 1, Unknown 1

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Trials (filtered) newest first · largest first

All 6 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Clinical Trial With Aprotinin in the Acute Respiratory Distress Syndrome Treatment
Aprotinin (inhaled), Placebo (Sodium Chloride) - Acute Respiratory Distress Syndrome (ARDS)
Phase 3RecruitingFundacion del Hospital Nacional de Paraplejicos para la Investigacion y la Integracion1562026-06-182026-07-15
Effect of Aprotinin on Transfusion Requirements in Patients Undergoing Elective Spinal Fusion Surgery
Trasylol (Aprotinin, BAYA0128), Placebo - Blood Loss, Surgical, Postoperative Hemorrhage
Phase 3TerminatedBayer542006-02-272019-06-04
Efficacy and Safety of Aprotinin on Transfusion Requirements in Patients Undergoing Radical or Total Cystectomy
Trasylol (Aprotinin, BAYA0128), Placebo - Blood Loss, Surgical, Postoperative Hemorrhage
Phase 3TerminatedBayer572005-12-012014-12-17
Study to Investigate the Effect of Aprotinin of Transfusion Requirements in Patients Undergoing Surgical Procedures for Lung or Esophageal Cancer
Trasylol (Aprotinin, BAYA0128), Placebo - Blood Loss, Surgical
Phase 3TerminatedBayer1042005-12-012014-12-09
Effect of Aprotinin on Transfusion Requirements and Blood Loss in Patients Undergoing Elective Primary Total Hip Replacement
Trasylol (Aprotinin, BAYA0128), Placebo - Blood Loss, Surgical
Phase 3CompletedBayer3592005-02-012014-12-30
Comparison of Aprotinin and Tranexamic Acid in Routine Cardiac Surgery
aprotinin or tranexamic acid - Bleeding and Cardiac Surgery, Allogeneic Blood Transfusion
Phase 3UnknownGerman Heart Center2202005-01-012006-11-07

Conditions studied

Blood Loss, Surgical (4)  ·  Postoperative Hemorrhage (2)  ·  Hemorrhage (1)  ·  Respiratory Distress Syndrome (1)

Sponsors

Bayer (4)  ·  Fundacion del Hospital Nacional de Paraplejicos para la Investigacion y la Integracion (1)  ·  German Heart Center (1)

Countries

Germany (4)  ·  Canada (3)  ·  Spain (3)  ·  United States (3)  ·  Belgium (2)  ·  France (2)  ·  United Kingdom (2)  ·  Australia (1)  ·  Austria (1)  ·  Denmark (1)  ·  Netherlands (1)  ·  Puerto Rico (1)  ·  Sweden (1)

Top investigators

Wulf Dietrich, MD, PhD (1)

Results publications

PMID 18931201, PMID 21127274

NIH funding

2005 (2), 2025 (1)