Examination of the Effects of Four Different Spices on Energy Metabolism

NCT00611156 — Not applicable, Completed, 22 participants, University of Copenhagen

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Bioactive Food Ingredients and Energy Metabolism: The Effects of Ginger, Black Pepper, Horseradish and Mustard on Meal-Induced Thermogenesis and Fat Oxidation

RegistryNCT00611156
StatusCompleted
PhaseNot applicable
Study typeInterventional; randomized, crossover, masking: single, prevention
Enrollment22 (Actual)
SponsorUniversity of Copenhagen (Other); collaborators: University of Aarhus
ConditionsHealthy
Interventionsginger, black pepper, horseradish, mustard, placebo (Dietary supplement)
Datesstart 2006-10-01, completion 2007-06-01, first posted 2008-02-08, last updated 2008-02-08
Locations1 site in Denmark

Related Papers Related Patents Related Grants Related Experts
All trials for Healthy All trials of ginger All trials of black pepper

-Summary

The objective of this study is to examine whether four different spices (ginger, black pepper, horseradish and mustard) are able to increase energy metabolism.

Since chili and other spices have been shown to increase energy expenditure compared to placebo, we expect that some or all of the four spices may actually increase energy expenditure - although not to a large degree.

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+Detailed description

Several pungent food ingredients, such as chili,and also other bioactive food ingredients, e.g. green tea, have been shown to be able to increase energy expenditure and fat oxidation during the hours following a meal containing the bioactive ingredient. Furthermore, we will also look at the subjects own feelings of appetite and thereby examine whether the appetite is affected by the spicy food. We expect to see some small effects on these parameters.

+Arms and interventions

ArmTypeInterventionsDescription
AExperimentalDietary Supplement: gingerSpice
BExperimentalDietary Supplement: black pepperSpice
CExperimentalDietary Supplement: horseradishSpice
DExperimentalDietary Supplement: mustardSpice
EPlacebo comparatorDietary Supplement: placeboPlacebo
  • ginger (Dietary supplement): added to a brunch meal
  • black pepper (Dietary supplement): Added to a brunch meal
  • horseradish (Dietary supplement): Added to a brunch meal
  • mustard (Dietary supplement): Added to a brunch meal
  • placebo (Dietary supplement): Added to a bruch meal

+Outcome measures

Primary outcomes

  • energy expenditure [November 2007]

Secondary outcomes

  • blood pressure [December 2007]
  • heart rate [December 2007]
  • VAS-scores for appetite, hunger, fullness, etc. - and palatability [November 2007]
  • tolerance [November 2007]
  • Fat and carbohydrate oxidation [November 2007]
  • Meal-induced thermogenesis [November 2007]

+Eligibility

Sex: Male, ages: 18 Years to 50 Years, accepts healthy volunteers

Inclusion Criteria:

* male
* healthy and not use medication (regularly)
* normal weight
* non smoker
* tolerate and like spicy food
* stable body weight last two months

Exclusion Criteria:

* increased blood pressure
* abnormal EKG
* mental, metabolic and chronic diseases

+Locations (1)

FacilityCityCountryStatus
Department of Human Nutrition, The Royal Veterinary and Agricultural UniversityFrederiksbergDenmark

+Publications

  • Results publication: Gregersen NT, Belza A, Jensen MG, Ritz C, Bitz C, Hels O, Frandsen E, Mela DJ, Astrup A. Acute effects of mustard, horseradish, black pepper and ginger on energy expenditure, appetite, ad libitum energy intake and energy balance in human subjects. Br J Nutr. 2013 Feb 14;109(3):556-63. doi: 10.1017/S0007114512001201. Epub 2012 Jul 5. PMID 23021155

+Investigators