106 completed, 31 terminated, 22 active not recruiting, 18 recruiting. 136 Phase 2, 58 Phase 1, 20 Not applicable, 15 Phase 3, 4 Early Phase 1.
Follow Allogeneic Hematopoietic Stem Cell Transplantation: new trials by email Literature Review of Allogeneic Hematopoietic Stem Cell Transplantation trials Research Report on Allogeneic Hematopoietic Stem Cell Transplantation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ²¹¹At-OKT10-B10 and Fludarabine Alone or in Combination With Cyclophosphamide and Low-Dose TBI Before Donor Stem Cell Transplant for the Treatment of Newly Diagnosed, Recurrent, or Refractory High-Risk Multiple Myeloma Allogeneic Hematopoietic Stem Cell Transplantation, Astatine At 211 Anti-CD38 Monoclonal Antibody OKT10-B10, Cyclophosphamide - Multiple Myeloma, Recurrent Multiple Myeloma | Phase 1 | Withdrawn | Fred Hutchinson Cancer Center | 2027-06-01 | 2026-09-11 | |
| Venetoclax or Placebo in Combination With Reduced-Intensity Conditioning Hematopoietic Cell (Bone Marrow/Blood Stem Cell) Transplant and as Maintenance Therapy After Transplant in Patients With Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial) Allogeneic Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Bone Marrow Biopsy - Acute Myeloid Leukemia | Phase 2 | Not yet recruiting | National Cancer Institute (NCI) | 244 | 2027-01-15 | 2026-10-20 |
| Arsenic Trioxide to Prevent Relapse in Patients Undergoing Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia or Myelodysplastic Syndrome Allogeneic Hematopoietic Stem Cell Transplantation, Arsenic Trioxide, Biospecimen Collection - Acute Myeloid Leukemia, Myelodysplastic Syndrome | Phase 1 | Not yet recruiting | University of Michigan Rogel Cancer Center | 20 | 2026-11-01 | 2026-07-30 |
| A Study of Azacitidine and Venetoclax Versus a Stem Cell Transplant in People 65 Years and Older With Acute Myeloid Leukemia Azacitidine (AZA), Venetoclax, Allogeneic hematopoietic stem cell transplantation - Acute Myeloid Leukemia | Phase 2 | Withdrawn | Memorial Sloan Kettering Cancer Center | 2026-08-04 | 2026-08-05 | |
| Axatilimab Plus Standard of Care Therapy for the Prevention of Graft Versus Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Hematologic Cancer, ABRAXAS Trial Allogeneic Hematopoietic Stem Cell Transplantation, Axatilimab, Biospecimen Collection - Hematopoietic and Lymphatic System Neoplasm | Phase 2 | Withdrawn | Mayo Clinic | 2026-06-01 | 2026-09-03 | |
| Ruxolitinib With Azacitidine Maintenance for the Treatment of Patients With Acute Myeloid Leukemia Undergoing Reduced Intensity Allogeneic Stem Cell Transplantation Allogeneic Hematopoietic Stem Cell Transplantation, Azacitidine, Biospecimen Collection - Acute Myeloid Leukemia | Phase 1 | Recruiting | OHSU Knight Cancer Institute | 40 | 2026-04-21 | 2026-10-05 |
| A Single-arm, Prospective Study of a Clad-LABU Conditioning Regimen in HSCT for R/R MDS/AML in Elderly Patients Allogeneic Hematopoietic Stem Cell Transplantation - Relapsed or Refractory Acute Myeloid Leukemia (AML), MDS (Myelodysplastic Syndrome) | Not applicable | Recruiting | The First Affiliated Hospital of Soochow University | 30 | 2026-04-01 | 2026-04-15 |
| Ruxolitinib Before, During and After Hematopoietic Cell Transplant in Older Patients With Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes Ruxolitinib, Allogeneic Hematopoietic Stem Cell Transplantation, Busulfan - Myelodysplastic/Myeloproliferative Neoplasm, Primary Myelofibrosis | Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 50 | 2026-02-04 | 2026-10-19 |
| Prehabilitation for Patients Diagnosed With Blood Cancer and Treated With Al-logeneic Hematopoietic Stem Cell Transplantation Resistance training, Nutritional Support, Usual care - Allogeneic Hematopoietic Stem Cell Transplantation Recipient | Not applicable | Recruiting | Copenhagen University Hospital, Rigshospitalet | 110 | 2026-01-12 | 2026-01-29 |
| Allogeneic CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Vaccine After Matched Related Donor Hematopoietic Cell Transplant for the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia Allogeneic Hematopoietic Stem Cell Transplantation, Anti-CD19-CAR CMV-specific T-lymphocytes, Biospecimen Collection - Acute Lymphoblastic Leukemia | Early Phase 1 | Recruiting | City of Hope Medical Center | 15 | 2025-12-30 | 2026-04-27 |
| Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer Allogeneic Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Bone Marrow Aspiration - Acute Leukemia of Ambiguous Lineage, Acute Myeloid Leukemia | Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 20 | 2025-09-26 | 2026-07-20 |
| Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Bone Marrow Biopsy - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 2 | Recruiting | City of Hope Medical Center | 35 | 2025-04-18 | 2026-06-29 |
| Full-course Immunotherapy Combined With Chemotherapy in Newly Diagnosed B-cell Acute Lymphoblastic Leukemia Blinatumomab, Induction Chemotherapy, Hyper-CVAD - B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative | Phase 2 | Recruiting | The First Affiliated Hospital of Soochow University | 101 | 2025-04-01 | 2026-05-04 |
| Humanized CD19-Specific CAR T Cells for the Treatment of Patients With Positive Relapsed or Refractory CD19 Positive B-Cell Acute Lymphoblastic Leukemia Allogeneic Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Bone Marrow Aspiration - Recurrent Acute Lymphoblastic Leukemia, Refractory Acute Lymphoblastic Leukemia | Phase 1 | Suspended | City of Hope Medical Center | 24 | 2024-11-06 | 2026-06-05 |
| CD7 CAR-T Bridging to alloHSCT for Severe Aplastic Anemia CD7 CAR-T cells injection, Allogeneic hematopoietic stem cell transplantation - Aplastic Anemia | Early Phase 1 | Recruiting | Zhejiang University | 30 | 2024-10-20 | 2024-10-09 |
| The Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation in Newly Diagnosed High-relapse-risk CEBPA Mutant Acute Myeloid Leukemia Allogeneic Hematopoietic Stem Cell Transplantation, Chemotherapy - Acute Myeloid Leukemia | Recruiting | Ruijin Hospital | 50 | 2024-10-19 | 2025-07-29 | |
| Magrolimab in Combination with Azacitidine After Allogeneic HCTin Treating Patients with High-Risk AML or MDS Allogeneic Hematopoietic Stem Cell Transplantation, Azacitidine, Biospecimen Collection - Acute Myeloid Leukemia, Myelodysplastic Syndrome | Phase 1 | Withdrawn | City of Hope Medical Center | 2024-10-09 | 2024-09-19 | |
| The Efficacy of Allo-HSCT in ND HR-CBF-AML Allogeneic Hematopoietic Stem Cell Transplantation, Chemotherapy - Acute Myeloid Leukemia | Recruiting | Ruijin Hospital | 90 | 2024-09-21 | 2026-04-16 | |
| CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant Allogeneic Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Granulocyte Colony-Stimulating Factor - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 2 | Recruiting | City of Hope Medical Center | 216 | 2024-07-12 | 2026-03-10 |
| MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial) Allogeneic Hematopoietic Stem Cell Transplantation, Azacitidine, Best Practice - Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm | Phase 2 | Recruiting | National Cancer Institute (NCI) | 2000 | 2024-06-18 | 2026-10-21 |
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Leukemia, Myeloid, Acute (104) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (85) · Myelodysplastic Syndromes (71) · Leukemia (59) · Congenital Abnormalities (57) · Leukemia, Lymphocytic, Chronic, B-Cell (56) · Multiple Myeloma (54) · Hodgkin Disease (53) · Lymphoma, Non-Hodgkin (53) · Lymphoma, Large B-Cell, Diffuse (46) · Lymphoma, Mantle-Cell (45) · Burkitt Lymphoma (43) · Lymphoma, Follicular (42) · Leukemia, Myeloid, Accelerated Phase (41) · Lymphoma, B-Cell, Marginal Zone (39)
Fred Hutchinson Cancer Center (47) · City of Hope Medical Center (27) · M.D. Anderson Cancer Center (19) · National Cancer Institute (NCI) (9) · Memorial Sloan Kettering Cancer Center (8) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (8) · Asan Medical Center (5) · Children's Oncology Group (5) · University of California, San Francisco (5) · Roswell Park Cancer Institute (4) · Barbara Ann Karmanos Cancer Institute (3) · Masonic Cancer Center, University of Minnesota (3) · The First Affiliated Hospital of Soochow University (3) · Alliance for Clinical Trials in Oncology (2) · Cancer Research UK (2)
United States (170) · China (12) · Italy (10) · Canada (9) · Germany (9) · Denmark (6) · France (6) · Puerto Rico (5) · South Korea (5) · United Kingdom (5) · Australia (4) · Austria (4) · Belgium (4) · Czechia (4) · Netherlands (4)
Brenda Sandmaier (7) · Kyoo H. Lee, MD (4) · Usama Gergis, MD (4) · Johnnie Orozco (3) · Uday R Popat (3) · Ajay Gopal (2) · Anthony S. Stein, MD (2) · Anthony Stein (2) · Asad Bashey, MD, PhD (2) · Chitra Hosing (2) · David Maloney (2) · Dolores Grosso, DNP, CRNP (2) · George Chen (2) · Haris Ali (2) · He Huang, MD (2)
PMID 32499241, PMID 35007144, PMID 16115130, PMID 17162214, PMID 19786617, PMID 19900571, PMID 21508413, PMID 21523798, PMID 21623761, PMID 21715313, PMID 21719601, PMID 23065508, PMID 23524640, PMID 24077846, PMID 24530972, PMID 25085357, PMID 25145344, PMID 26053664, PMID 26210442, PMID 26527780, PMID 26764356, PMID 27480385, PMID 29360184, PMID 29618479, PMID 29769208, PMID 30454872, PMID 31212080, PMID 31248843, PMID 31283407, PMID 31582553, PMID 31637757, PMID 31869413, PMID 32325461, PMID 32589970, PMID 32603426, PMID 32710011, PMID 32730187, PMID 33405950, PMID 33651090, PMID 33843815, PMID 33858040, PMID 34048072, PMID 34120773, PMID 34162404, PMID 34312462, PMID 34477813, PMID 34492682, PMID 34581764, PMID 35358441, PMID 35358442
P30CA015704 (28), P30CA033572 (16), P01CA018029 (10), P30CA016672 (5), P01CA044991 (4), P01CA078902 (4), P01HL036444 (4), U10CA180821 (4), U10CA180886 (4), U10CA031946 (3), U10CA180888 (3), P30CA022453 (2), P30CA036727 (2), P30CA072720 (2), R01CA154491 (2)