5 completed, 2 terminated. 4 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Completed 3, Terminated 1 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
Follow alfimeprase: new trials by email Literature Review of alfimeprase trials Research Report on alfimeprase
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 2 Proof-of-Concept Study of the Safety and Efficacy of Alfimeprase to Rapidly Open Arteries and Restore Brain Function Following a Stroke alfimeprase - Acute Ischemic Stroke | Phase 2 | Terminated | ARCA Biopharma, Inc. | 7 | 2007-06-01 | 2008-04-24 |
| Study of Alfimeprase's Ability to Dissolve Blood Clots in the Leg and Help Prevent the Need for Surgery alfimeprase - Arterial Occlusive Diseases | Phase 3 | Terminated | ARCA Biopharma, Inc. | 300 | 2006-04-01 | 2008-01-15 |
| Safety and Efficacy Study of Alfimeprase in Subjects With Occluded Catheters Alfimeprase - Thrombosis, Venous Thrombosis | Phase 3 | Completed | ARCA Biopharma, Inc. | 2006-01-01 | 2008-08-15 | |
| Safety and Efficacy Study of Alfimeprase in Subjects With Occluded Central Catheters Alfimeprase - Thrombosis, Venous Thrombosis | Phase 3 | Completed | ARCA Biopharma, Inc. | 300 | 2005-09-01 | 2008-08-14 |
| Study of Alfimeprase to Rapidly Dissolve Blood Clots in the Leg and Help Prevent the Need for Surgery on Leg Arteries alfimeprase - Arterial Occlusive Diseases | Phase 3 | Completed | ARCA Biopharma, Inc. | 300 | 2005-04-01 | 2008-01-15 |
| Alfimeprase for Thrombolysis in Acute Peripheral Arterial Occlusion Alfimeprase - Arterial Occlusive Diseases, Peripheral Vascular Diseases | Phase 2 | Completed | ARCA Biopharma, Inc. | 100 | 2003-06-01 | 2009-12-17 |
| Trial of a Novel Fibrinolytic (Alfimeprase) to Clear Thrombosed Vascular Access Devices Alfimeprase - Catheters, Indwelling | Phase 2 | Completed | ARCA Biopharma, Inc. | 115 | 2010-02-03 |
Thrombosis (7) · Arterial Occlusive Diseases (3) · Embolism (2) · Intermittent Claudication (2) · Thromboembolism (2) · Venous Thrombosis (2) · Ischemic Stroke (1) · Peripheral Vascular Diseases (1) · Stroke (1)
United States (7) · Canada (1)
Mohammad Hirmand, MD (1) · Steven Deitcher, M.D. (1) · Steven R Deitcher, MD (1) · Susan Begelman, M.D. (1) · Susan M Begelman, MD (1)