10 completed. 10 Phase 1, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 10 |
| Phase 2 | 6 | Completed 6 |
Follow acyline: new trials by email Literature Review of acyline trials Research Report on acyline
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| T-IR- Study to Understand the Effects of Testosterone and Estrogen on the Body's Response to the Hormone Insulin Acyline, Testosterone 1.62% gel, Letrozole - Insulin Resistance, Type 2 Diabetes Mellitus | Phase 1 / Phase 2 | Completed | University of Washington | 53 | 2013-06-01 | 2018-05-08 |
| ITT4 Intratesticular Hormonal Milieu in Man (ITT4) Acyline, Testosterone gel, ketoconazole 400 - Healthy Males | Phase 1 / Phase 2 | Completed | University of Washington | 46 | 2011-01-01 | 2014-03-31 |
| ORAL T-8 Oral Testosterone for Male Hormonal Contraception Oral Testosterone, Acyline - Healthy | Phase 1 | Completed | University of Washington | 14 | 2010-07-01 | 2013-09-06 |
| HOP-3 Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone Acyline, placebo hCG (no active ingredient), hCG (human chorionic gonadotropin) - Healthy Males | Phase 1 / Phase 2 | Completed | University of Washington | 59 | 2009-03-01 | 2016-01-11 |
| ORAL T-6: Oral Androgens in Man-6 Acyline, Testosterone, Finasteride - Contraception, Hypogonadism | Phase 1 | Completed | University of Washington | 16 | 2008-10-01 | 2011-01-24 |
| ACY-7 Oral Administration of Acyline Acyline - Healthy | Phase 1 / Phase 2 | Completed | University of Washington | 4 | 2008-01-01 | 2011-06-09 |
| ACY-6 Oral Administration of Acyline Acyline - Contraception | Phase 1 | Completed | University of Washington | 9 | 2007-06-01 | 2010-12-03 |
| Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone (HOP 5) Testicular Aspiration Addendum Acyline, Testosterone Gel, Depo-Medroxyprogesterone - Contraception | Phase 1 / Phase 2 | Completed | University of Washington | 23 | 2004-12-01 | 2008-09-19 |
| The Effects of Testosterone on Prostate Tissue (ACYP-1) Testosterone gel, Acyline, Placebo acyline - Hypogonadism, Contraception | Phase 1 | Completed | University of Washington | 13 | 2004-07-01 | 2008-09-19 |
| Male Hormonal Contraceptive Development-ACY-5 Acyline, Testosterone Gel, Depo-Medroxyprogesterone - Contraception | Phase 1 / Phase 2 | Completed | University of Washington | 43 | 2004-05-01 | 2008-09-19 |
Hypogonadism (2) · Diabetes Mellitus, Type 2 (1) · Insulin Resistance (1) · Metabolic Diseases (1) · Obesity (1)
United States (10)
John K Amory (2) · William J Bremner, MD, PhD (2) · John K Amory, MD (1) · John K Amory, MD, MPH (1) · Katya Rubinow, MD (1) · Mara Y Roth, MD (1) · Stephanie T Page, MD, PhD (1) · William Bremner, MD (1) · William Bremner, MD, PhD (1) · William J Bremner, MD (1)
PMID 17494097, PMID 20378927, PMID 16352669, PMID 16882745, PMID 16940442, PMID 17303493, PMID 17510436, PMID 20484472, PMID 23040523, PMID 23348398, PMID 27482750, PMID 29793828
U54HD012629 (2), U54HD042454 (2), K23HD045386 (1)