3 completed. 3 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 3 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 1 | Completed 1 |
Follow 2-Hydroxypropyl-beta-cyclodextrin: new trials by email Literature Review of 2-Hydroxypropyl-beta-cyclodextrin trials Research Report on 2-Hydroxypropyl-beta-cyclodextrin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C VTS-270 - Niemann-Pick Disease, Type C | Phase 1 / Phase 2 | Completed | Washington University School of Medicine | 4 | 2019-02-22 | 2026-01-05 |
| Safety and Efficacy of Intravenous Trappsol Cyclo (HPBCD) in Niemann-Pick Type C Patients Hydroxypropyl-beta-cyclodextrin - Niemann-Pick Disease, Type C1 | Phase 1 / Phase 2 | Completed | Cyclo Therapeutics, Inc. | 12 | 2017-03-20 | 2021-08-10 |
| VTS-270 to Treat Niemann-Pick Type C1 (NPC1) Disease Parts A/B: Adrabetadex, Parts A/B: Sham Control - Niemann-Pick Disease, Type C | Phase 2 / Phase 3 | Completed | Mandos LLC | 56 | 2015-10-01 | 2023-02-22 |
Niemann-Pick Disease, Type C (3) · Cognitive Dysfunction (1) · Deglutition Disorders (1) · Disease (1) · Mobility Limitation (1)
Cyclo Therapeutics, Inc. (1) · Mandos LLC (1) · Washington University School of Medicine (1)
United Kingdom (2) · United States (2) · Australia (1) · France (1) · Germany (1) · Israel (1) · New Zealand (1) · Singapore (1) · Spain (1) · Sweden (1) · Turkey (Türkiye) (1)
Patricia I Dickson, MD (1) · Reena Sharma, MB BS (1)
2015 (1), U01HD090845 (1)