4 completed. 4 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 4 |
| Phase 2 | 2 | Completed 2 |
Follow 2-Hydroxypropyl-beta-cyclodextrin: new trials by email Literature Review of 2-Hydroxypropyl-beta-cyclodextrin trials Research Report on 2-Hydroxypropyl-beta-cyclodextrin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C VTS-270 - Niemann-Pick Disease, Type C | Phase 1 / Phase 2 | Completed | Washington University School of Medicine | 4 | 2019-02-22 | 2026-01-05 |
| Study of the Pharmacokinetics of Trappsol and Effects on Potential Biomarkers of Niemann-Pick C1 (NPC1) Hydroxypropyl-beta-cyclodextrin - Niemann-Pick Disease, Type C1 | Phase 1 | Completed | Cyclo Therapeutics, Inc. | 13 | 2017-10-11 | 2021-02-21 |
| Safety and Efficacy of Intravenous Trappsol Cyclo (HPBCD) in Niemann-Pick Type C Patients Hydroxypropyl-beta-cyclodextrin - Niemann-Pick Disease, Type C1 | Phase 1 / Phase 2 | Completed | Cyclo Therapeutics, Inc. | 12 | 2017-03-20 | 2021-08-10 |
| Hydroxypropyl Beta Cyclodextrin for Niemann-Pick Type C1 Disease VTS-270 - Niemann-Pick Disease, Type C1 | Phase 1 | Completed | Vtesse, LLC, a Mallinckrodt Pharmaceuticals Company | 14 | 2013-01-01 | 2021-07-23 |
Niemann-Pick Disease, Type C (4) · Nerve Degeneration (1)
Cyclo Therapeutics, Inc. (2) · Vtesse, LLC, a Mallinckrodt Pharmaceuticals Company (1) · Washington University School of Medicine (1)
United States (3) · Israel (1) · Sweden (1) · United Kingdom (1)
Caroline Hastings, MD (1) · Patricia I Dickson, MD (1) · Reena Sharma, MB BS (1)
PMID 31187454, PMID 34810067, PMID 36279795, PMID 37670901, PMID 40525490
U01HD090845 (1)